Evaluation of prebiotic activities of Salvia species as potential functional components for intestinal health

Mevlüde Nur Dilgen; Betül Aydın; Murat Koç

Evaluation of prebiotic activities of Salvia species as potential functional components for intestinal health

Abstract

Some Salvia species have long been used in traditional medicine for digestive disorders. This study investigated the prebiotic potential of water and ethanol extracts of Salvia fruticosa, S. huberi, S. sclarea, and S. aethiopis on probiotic bacteria Lactobacillus fermentum ATCC 14931 and L. plantarum ATCC 8014. Among the tested species, the extracts of S. huberi and S. sclarea exhibited the highest prebiotic activity. The ethanol extract of S. huberi showed prebiotic activity scores comparable to commercial prebiotics. Under simulated gastrointestinal conditions, the S. huberi water extract significantly increased the survival of L. fermentum, while the S. sclarea water and ethanol extracts provided the highest viability rate for L. plantarum. Both species provided the highest cell surface hydrophobicity values and strong post-fermentation antioxidant activity; S. huberi water extract reached the radical scavenging rate. The present in vitro findings suggest that S. huberi and S. sclarea are promising candidates with potential prebiotic properties that may contribute to probiotic viability and gut health.

Keywords

Supporting Institution

None.

Project Number

None.

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Details

Primary Language

English

Subjects

Plant Biochemistry

Journal Section

Research Article

Authors

Mevlüde Nur Dilgen ^*
0000-0002-9720-8662
Türkiye

Betül Aydın
0000-0002-9092-1350
Türkiye

Murat Koç
0000-0002-0829-4571
Türkiye

Early Pub Date

July 25, 2026

Publication Date

-

Submission Date

August 14, 2025

Acceptance Date

April 28, 2026

Published in Issue

Year 2026 Number: Advanced Online Publication

IZ

https://izlik.org/JA89PT26HB

Cite

RIS / Bibtex

APA

Dilgen, M. N., Aydın, B., & Koç, M. (2026). Evaluation of prebiotic activities of Salvia species as potential functional components for intestinal health. International Journal of Secondary Metabolite, Advanced Online Publication. https://izlik.org/JA89PT26HB

AMA

1.Dilgen MN, Aydın B, Koç M. Evaluation of prebiotic activities of Salvia species as potential functional components for intestinal health. Int. J. Sec. Metabolite. 2026;(Advanced Online Publication). https://izlik.org/JA89PT26HB

Chicago

Dilgen, Mevlüde Nur, Betül Aydın, and Murat Koç. 2026. “Evaluation of Prebiotic Activities of Salvia Species As Potential Functional Components for Intestinal Health”. International Journal of Secondary Metabolite, no. Advanced Online Publication. https://izlik.org/JA89PT26HB.

EndNote

Dilgen MN, Aydın B, Koç M (July 1, 2026) Evaluation of prebiotic activities of Salvia species as potential functional components for intestinal health. International Journal of Secondary Metabolite Advanced Online Publication

IEEE

[1]M. N. Dilgen, B. Aydın, and M. Koç, “Evaluation of prebiotic activities of Salvia species as potential functional components for intestinal health”, Int. J. Sec. Metabolite, no. Advanced Online Publication, July 2026, [Online]. Available: https://izlik.org/JA89PT26HB

ISNAD

Dilgen, Mevlüde Nur - Aydın, Betül - Koç, Murat. “Evaluation of Prebiotic Activities of Salvia Species As Potential Functional Components for Intestinal Health”. International Journal of Secondary Metabolite. Advanced Online Publication (July 1, 2026). https://izlik.org/JA89PT26HB.

JAMA

1.Dilgen MN, Aydın B, Koç M. Evaluation of prebiotic activities of Salvia species as potential functional components for intestinal health. Int. J. Sec. Metabolite. 2026. Available at https://izlik.org/JA89PT26HB.

MLA

Dilgen, Mevlüde Nur, et al. “Evaluation of Prebiotic Activities of Salvia Species As Potential Functional Components for Intestinal Health”. International Journal of Secondary Metabolite, no. Advanced Online Publication, July 2026, https://izlik.org/JA89PT26HB.

Vancouver

1.Mevlüde Nur Dilgen, Betül Aydın, Murat Koç. Evaluation of prebiotic activities of Salvia species as potential functional components for intestinal health. Int. J. Sec. Metabolite [Internet]. 2026 Jul. 1;(Advanced Online Publication). Available from: https://izlik.org/JA89PT26HB