Plant Taxa Used in the Treatment of Diabetes in Van Province, Turkey

Öz

Despite the richness of local flora and medicinal plant utilization, there is no any report on documentation of antidiabetic botanicals used in Van province. Therefore, the present study aimed to record accumulation of the traditional antidiabetic medicinal plants of Van province in order to preserve the valuable local medicines knowledge, which has been threatened by urbanization. Antidiabetic folk medicines were determined via field surveys conducted in 1065 settlements during the period of 2014-2017 through medicinal plants questionnaire and structured face-to-face interviews (600 informants) with local people who are well known in the province for their long practice in traditional medicine. 69 plant taxa (35 species with undocumented antidiabetic medicinal use in scientific literature for Turkey) including five endemic and one rare to Turkey belong to 16 families (principally Asteraceae and Lamiaceae) were recorded for their traditional antidiabetic use. 52 different vernacular names were detected which were mainly indicate morphological characteristics. Infusion prepared from leaf and flower organs were found as the most common preparation method of local medicines in the province. Use value analysis showed that Rheum ribes, Urtica dioica, Scutelleria orientalis subsp. pichleri, Diplotenia cachrydifolia, Teucrium polium, Rosa canina, Campanula glomerata subsp. hispida, Rumex scutatus, Helichrysum plicatum subsp. plicatum and Tanacetum balsamita subsp. balsamita might serve promising pharmaceutical agents for diabetes treatment.

Anahtar Kelimeler

• Diabetes
• Medicinal Plants
• Van
• Asteraceae

Plant Taxa Used in the Treatment of Diabetes in Van Province, Turkey

Abstract

Despite the richness of local flora and medicinal plant utilization, there is no any report on documentation of antidiabetic botanicals used in Van province. Therefore, the present study aimed to record accumulation of the traditional antidiabetic medicinal plants of Van province in order to preserve the valuable local medicines knowledge, which has been threatened by urbanization. Antidiabetic folk medicines were determined via field surveys conducted in 1065 settlements during the period of 2014-2017 through medicinal plants questionnaire and structured face-to-face interviews (600 informants) with local people who are well known in the province for their long practice in traditional medicine. 69 plant taxa (35 species with undocumented antidiabetic medicinal use in scientific literature for Turkey) including five endemic and one rare to Turkey belong to 16 families (principally Asteraceae and Lamiaceae) were recorded for their traditional antidiabetic use. 52 different vernacular names were detected which were mainly indicate morphological characteristics. Infusion prepared from leaf and flower organs were found as the most common preparation method of local medicines in the province. Use value analysis showed that Rheum ribes, Urtica dioica, Scutelleria orientalis subsp. pichleri, Diplotenia cachrydifolia, Teucrium polium, Rosa canina, Campanula glomerata subsp. hispida, Rumex scutatus, Helichrysum plicatum subsp. plicatum and Tanacetum balsamita subsp. balsamita might serve promising pharmaceutical agents for diabetes treatment.

Keywords

• Diabetes
• Medicinal Plants
• Van
• Asteraceae

References

1. American Diabetes Association (2012). Diagnosis and classification of diabetes mellitus. Diabetes Care, 35 (Suppl.), 64-71.
2. Wild, S., Roglic, G., Green, A., Sicree, R., King, H. (2004). Global prevalence of Diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care, 27(5), 1047-1053.
3. Bedekar, A., Shah, K., Koffas, M. (2010). Natural products for type II diabetes treatment. In Advances in Applied Microbiology, Burlington: Academic Press, 71, 21-73.
4. Rates, S.M.K. (2001). Plants as source of drugs. Toxicon, 39, 603-613.
5. Davis, P.H. (1965-1985). Flora of Turkey and the East Aegean lslands. Volumes: 1-9, first edit, Edinburgh: Edinburgh Univ. Press.
6. Rechinger, K.H. (1965-1977). Flora Iranica. Graz – Austria, Graz: Akademisch Drucku Verlangsanstalt.
7. Towsend, C.C., Guest, E. (1966-1985). Flora of Iraq. Vol. 1-9, first ed. Baghdad: Ministry of Agriculture Republic of Iraq.
8. Davis, P.H., Mill, R.R., Tan, K. (1988). Flora of Turkey and the East Aegean Islands. Volume: 10 (supplement I), first ed. Edinburgh: Edinburgh Univ. Press.

9. Güner, A. Özhatay, N. Ekim, T., Başer, K. (2000). Flora of Turkey and the East Aegean Islands. Vol: 11. (Suplement II), first ed. Edinburgh: Edinburgh Univ. Press.
10. Ekim, T., Koyuncu, M., Vural, M., Duman, H., Aytaç, Z., Adıgüzel, N. (2010). Türkiye Bitkileri Kırmızı Kitabı, first ed. Ankara: Türkiye Tabiatını Koruma Derneği, Van 100.Yıl Üniversitesi.
11. IUCN (2001). Red List Categories: Version 3.1. IUCN Species Survival Commission, Gland, Switzerland.
12. Kaval, İ., Behçet, L., Çakılcıoglu, U. (2014). Ethnobotanical study on medicinal plants in Geçitli and its surrounding (Hakkari-Turkey). Journal of Ethnopharmacology, 155, 171–184.
13. Mükemre, M., Behçet, L., Çakılcıoğlu, U. (2015). Ethnobotanical study on medicinal plants in villages of Çatak (Van-Turkey). Journal of Ethnopharmacology, 166, 361-374.
14. Günes, F., Özhatay, N. (2011). An ethnobotanical study from Kars (Eastern) Turkey. Biological Diversity and Conservation, 4, 30–41.
15. Altundağ, E., Öztürk, M. (2011). Ethnomedicinal Studies on The Plant Resources of East Anatolia, Turkey. Procedia Social and Behavioral Sciences, 19, 756-777
16. Güneş, S., Savran, A., Paksoy, M. Y., Koşar, M. (2017). Ethnopharmacological survey of medicinal plants in Karaisalı and its surrounding (Adana-Turkey). Journal of Herbal Medicine, 8, 68-75.
17. Kültür, Ş. (2007). Medicinal Plants Used in Kırklareli Province (Turkey). Journal of Ethnopharmacology, 111, 341-364.
18. Sargın, S.A., Selvi, S., López, V. (2015). Ethnomedicinal plants of Sarigöl district (Manisa), Turkey. Journal of Ethnopharmacology, 171, 64-84.
19. Güzel, Y., Güzelşemme, M., Miski, M. (2015). Ethnobotany of medicinal plants used in Antakya: A multicultural district in Hatay Province of Turkey. Journal of Ethnopharmacology, 174, 118-152.
20. Paksoy, M., Y., Selvi, S., Savran, A. (2016). Ethnopharmacological survey of medicinal plants in Ulukışla (Niğde-Turkey). Journal of Herbal Medicine, 1(6), 42-48.
21. Sezik, E., Yeşilada, E., Honda, G., Takaishi, Y., Takeda, Y., Tanaka, T. (2001). Traditional Medicine in Turkey X. Folk Medicine in Central Anatolia, Journal of Ethnopharmacology, 75, 95-115.
22. Çakılcıoğlu, U., Şengün, M.T., Türkoğlu, İ. (2010). An Ethnobotanical Survey of Medicinal Plants of Yazıkonak and Yurtbaşı Districts of Elazığ Province, Turkey. Journal of Medicinal Plants Research, 4(7), 567-572.
23. Polat, R., Çakılcıoglu, U., Satıl, F. (2013). Traditional uses of medicinal plants in Solhan (Bingöl-Turkey). Journal of Ethnopharmacology, 148, 951–963.
24. Baytop, T. (1999). Türkiye’de Bitkilerle Tedavi: Geçmişte ve Bugün. İstanbul: Nobel Tıp Kitapevleri.
25. Bulut, G., Tuzlacı, E. (2013). Ethnobotanical study on medicinal plants in Turgutlu (Manisa-Turkey). Journal of Ethnopharmacology, 149, 633-647.
26. Çakılcıoğlu, U., Khatun, S., Türkoğlu, İ., Hayta, Ş. (2011). Ethnopharmacological Survey of Medicinal Plants in Maden (Elazıg-Turkey). Journal of Ethnopharmacology, 137, 469-486.
27. Tetik, F., Civelek, S., Çakılcıoglu, U. (2013). Traditional uses of some medicinal plants in Malatya (Turkey). Journal of Ethnopharmacology 146, 331–346.
28. Demirci, S., Özhatay, N. (2012). An ethnobotanical study in Kahramanmaraş (Turkey); wild plants used for medicinal purpose in Andırın, Kahramanmaraş. Turkish Journal of Pharmaceutical Sciences, 9, 75–92.
29. Polat, R., Satıl, F. (2012). An Ethnobotanical Survey of Medicinal Plants in Edremit Gulf (BalıkesirTurkey). Journal of Ethnopharmacology, 139, 626-641,
30. Sargın, S.A. (2015). Ethnobotanical survey of medicinal plants in Bozyazı district of Mersin, Turkey. Journal of Ethnopharmacology, 173, 105-126.
31. Tuzlacı, E., Tolon, E. (2000). Turkish Folk Medicinal Plants, Part III: Şile (Istanbul), Fitoterapia, 71, 673-685.
32. Özgen, U., Kaya, Y., Houghton, P. (2012). Folk medicines in the villages of Ilıca District (Erzurum), Turkey. Turkish Journal of Biology, 36, 93–106.
33. Polat, R., Çakılcıoglu, U., Kaltalioğlu, K., Ulusan, M.D., Türkmen, Z. (2015). An ethnobotanical study on medicinal plants in Espiye and its surrounding (Giresun-Turkey). Journal of Ethnopharmacology, 163, 1-11.
34. Hayta, S., Polat, R., Selvi, S. (2014). Traditional uses of medicinal plants in Elazıg (Turkey). Journal of Ethnopharmacology, 154, 613–623.
35. Özdemir, E., Alpınar, K. (2015). An ethnobotanical survey of medicinal plants in western part of central Taurus Mountains: Aladaglar (Nigde – Turkey). Journal of Ethnopharmacology, 166, 53-65.
36. Kızılarslan, Ç., Özhatay, N. (2012). Wild Plants Used as Medicinal Purpose in the South Part of İzmit (Northwest Turkey). Turkish Journal of Pharmaceutical Sciences, 9(2), 199-218.
37. Özüdoğru, B, Akaydın, G., Erik, S., Yeşilada, E. (2011). Inferences from an Ethnobotanical Field Expedition in the Selected Locations of Sivas and Yozgat Provinces (Turkey). Journal of Ethnopharmacology, 137, 85-98.
38. Royal Botanic Gardens Kew. State of the World’s Plants 2017: Useful Plants. https://stateoftheworldsplants.com/2017/ (accessed 09 April, 2018).
39. Güner, A., Aslan, S. Ekim, T. Vural, M., Babaç, M.T. (2012). Türkiye Bitkileri Listesi (Damarlı Bitkiler). First edit. İstanbul: Nezahat Gökyiğit Botanik Bahçesi Yayınları Flora Dizisi 1.
40. Harborne, J.B, Williams, C.A. (2000). Advances in flavonoid research since 1992. Phytochemistry, 55, 481-504.
41. Sargin, S.A., Akçicek, E., Selvi, S. (2013). An ethnobotanical study of medicinal plants used by the local people of Alaşehir (Manisa) in Turkey. Journal of Ethnopharmacology, 150(3), 860-874.
42. Karaköse, M., Karaköse, G.Ç. (2017). Medicinal and Aromatic Plants of Esenli (Giresun) Forest Planning Unit. International Journal of Secondary Metabolite, 4(3), 285-305.