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Biological evaluation of Stachys iberica subsp. stenostachya (Boiss.) Rech.f. and Scutellaria orientalis subsp. sosnowskyi (Takht.) Fed. growing in eastern Anatolia

Year 2021, Volume: 8 Issue: 4, 364 - 375, 26.12.2021
https://doi.org/10.21448/ijsm.979820

Abstract

Lamiaceae is one of the largest families in the plant kingdom, including the genus Stachys and Scutellaria, which are used in many folk medicines throughout the world for the prevention and also the treatment of several disorders. In vitro biological potential of Stachys iberica subsp. stenostachya and Scutellaria orientalis subsp. sosnowskyi were investigated in the current study. The aerial parts of the plants were extracted using different solvents such as n-hexane, chloroform, and methanol. In addition, infusions of each plant were prepared. The antioxidant potential of the samples was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), ABTS assays, ferrous ion-chelating, and ferric reducing antioxidant power (FRAP) assays. Anticholinesterase activity of the extracts was also determined. Spectrophotometric analysis was used to assess the total phenolic content of the samples. The antimicrobial activities of samples were determined by minimal inhibitory concentration (MIC) against seven bacteria and three Candida spp. yeast. According to the findings, the infusion demonstrated significant antioxidant properties, whilst the extracts demonstrated high-to-moderate antioxidant effects. The n-hexane extracts showed higher antifungal activity against C.parapsilosis and C.tropicalis. These outcomes suggest that these two species from Turkey could be employed in the manufacture of phytopharmaceuticals.

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Biological evaluation of Stachys iberica subsp. stenostachya (Boiss.) Rech.f. and Scutellaria orientalis subsp. sosnowskyi (Takht.) Fed. growing in eastern Anatolia

Year 2021, Volume: 8 Issue: 4, 364 - 375, 26.12.2021
https://doi.org/10.21448/ijsm.979820

Abstract

Lamiaceae is one of the largest families in the plant kingdom, including the genus Stachys and Scutellaria, which are used in many folk medicines throughout the world for the prevention and also the treatment of several disorders. In vitro biological potential of Stachys iberica subsp. stenostachya and Scutellaria orientalis subsp. sosnowskyi were investigated in the current study. The aerial parts of the plants were extracted using different solvents such as n-hexane, chloroform, and methanol. In addition, infusions of each plant were prepared. The antioxidant potential of the samples was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), ABTS assays, ferrous ion-chelating, and ferric reducing antioxidant power (FRAP) assays. Anticholinesterase activity of the extracts was also determined. Spectrophotometric analysis was used to assess the total phenolic content of the samples. The antimicrobial activities of samples were determined by minimal inhibitory concentration (MIC) against seven bacteria and three Candida spp. yeast. According to the findings, the infusion demonstrated significant antioxidant properties, whilst the extracts demonstrated high-to-moderate antioxidant effects. The n-hexane extracts showed higher antifungal activity against C.parapsilosis and C.tropicalis. These outcomes suggest that these two species from Turkey could be employed in the manufacture of phytopharmaceuticals.

References

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  • Elfalleh, W., Kirkan, B., Sarikurkcu, C. (2019). Antioxidant potential and phenolic composition of extracts from Stachys tmolea: An endemic plant from Turkey. Ind. Crops Prod., 127, 212-216. https://doi.org/10.1016/j.indcrop.2018.10.078
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  • İçen, M.S., Arabaci, T., Kostekci, S., Gürhan, İ. (2016). Chemical Composition of the Essential Oil of Scutellaria orientalis L. subsp. virens Boiss. & Kotschy JR Edm. from Turkey. Hacettepe J. Biol. Chem., 44(1), 25-28. https://doi.org/10.15671/HJBC.20164417563
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There are 51 citations in total.

Details

Primary Language English
Subjects Structural Biology
Journal Section Articles
Authors

Gizem Gulsoy Toplan 0000-0002-0544-2532

Ayşe Civaş 0000-0002-8838-3856

Emel Mataracı Kara 0000-0002-4428-5066

Turgut Taşkın 0000-0001-8475-6478

Gülay Ecevit Genç 0000-0002-1441-7427

Publication Date December 26, 2021
Submission Date August 6, 2021
Published in Issue Year 2021 Volume: 8 Issue: 4

Cite

APA Gulsoy Toplan, G., Civaş, A., Mataracı Kara, E., Taşkın, T., et al. (2021). Biological evaluation of Stachys iberica subsp. stenostachya (Boiss.) Rech.f. and Scutellaria orientalis subsp. sosnowskyi (Takht.) Fed. growing in eastern Anatolia. International Journal of Secondary Metabolite, 8(4), 364-375. https://doi.org/10.21448/ijsm.979820
International Journal of Secondary Metabolite

e-ISSN: 2148-6905