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Assessment of antioxidant and enzyme inhibition properties of Myrtus communis L. leaves

Year 2023, Volume: 10 Issue: 2, 166 - 174, 16.06.2023
https://doi.org/10.21448/ijsm.1106464

Abstract

This study investigated the antioxidant and enzyme inhibitory properties of Myrtus communis leaves. Three different solvents including methanol, 50%-methanol, and water were used to extract of M. communis. In addition, total bioactive compounds were evaluated by using total phenolic and total flavonoid content assays. In antioxidant assays, water extract displayed the highest antioxidant potential. The MeOH extract demonstrated the highest inhibitory effect against AChE (4.38 mg GALAE/g), BChE (1.58 mg GALAE/g), α-amylase (0.56 mmol ACE/g), and tyrosinase (132.20 mg KAE/g). The M. communis leaves extract could be used as a promising raw material source in food and medicine industries.

References

  • Abdulhadi, S.M., Shami, A.M., & Saleh, M.M. (2020). Antibacterial effect, Antioxidant potential and total phenolic content of polyphenol extracts of Myrtus communis leaves. Plant Archives, 20(2), 286-291.
  • Alkaltham, M.S., Salamatullah, A.M., Özcan, M.M., Uslu, N., Hayat, K., & Mohamed Ahmed, I.A. (2021). Influence of different drying methods on antioxidant activity, total phenol, and phenolic compounds of myrtle (Myrtus communis L.) fruits. Journal of Food Processing and Preservation, 45(4), e15308. https://doi.org/10.1111/jfpp.15308
  • Amensour, M., Bouhdid, S., Fernández-López, J., Idaomar, M., Senhaji, N.S., & Abrini, J. (2010). Antibacterial activity of extracts of Myrtus communis against food-borne pathogenic and spoilage bacteria. International Journal of Food Properties, 13(6), 1215–1224. https://doi.org/10.1080/10942910903013399
  • Chryssavgi, G., Vassiliki, P., Athanasios, M., Kibouris, T., & Michael, K. (2008). Essential oil composition of Pistacia lentiscus L. and Myrtus communis L.: evaluation of antioxidant capacity of methanolic extracts. Food Chemistry, 107(3), 1120 1130. https://doi.org/10.1016/j.foodchem.2007.09.036
  • Chu, S.C. & Chen, C. (2006). Effects of origins and fermentation time on the antioxidant activities of kombucha. Food Chemistry, 98(3), 502–507. https://doi.org/10.1016/j. foodchem.2005.05.080
  • D’Urso, G., Sarais, G., Lai, C., Pizza, C., & Montoro, P. (2017). LC-MS based metabolomics study of different parts of myrtle berry from Sardinia (Italy). Journal of Berry Research, 7(3), 217-229. https://doi.org/10.3233/JBR-170158
  • Engwa, G.A. (2018). Free Radicals and the Role of Plant Phytochemicals as Antioxidants Against Oxidative Stress-Related Diseases. in: Phytochemicals - Source of Antioxidants and Role in Disease Prevention. https://doi.org/10.5772/intechopen.76719
  • Fan, L.Y., & Chiu, M.J. (2014). Combotherapy and current concepts as well as future strategies for the treatment of Alzheimer’s disease. Neuropsychiatric Disease and Treatment, 10, 439–451. https://doi.org/10.2147/NDT.S45143
  • Hennia, A., Miguel, M.G., & Nemmiche, S. (2018). Antioxidant activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. extracts: A brief review. Medicines, 5(3), 89. https://doi.org/10.3390/medicines5030089 Hur, S.J., Lee, S.Y., Kim, Y.C., Choi, I., & Kim, G.B. (2014). Effect of fermentation on the antioxidant activity in plant-based foods. Food Chemistry, 160, 346–356. https://doi.org/10.1016/j.foodchem.2014.03.112
  • Ibrahim, F., Fouad, R., El-Hallouty, S., Hendawy, S.F., Omer, E. A., & Mohammed, R.S. (2021). Egyptian Myrtus communis L. Essential oil Potential role as in vitro Antioxidant, Cytotoxic and α-amylase Inhibitor. Egyptian Journal of Chemistry, 64(6), 3005-3017. https://doi.org/10.21608/EJCHEM.2021.57354.3245
  • Kamboj, V.P. (2000). Herbal medicine. Current Science, 78(1), 35 39. https://www.jstor.org/stable/24103844
  • Kumar, S., & Pandey, A.K. (2013). Chemistry and biological activities of flavonoids: an overview. The Scientific World Journal, 2013, 162750. https://doi.org/10.1155/2013/162750
  • Lee, C.E., & Petersen, C.H. (2003). Effects of Developmental Acclimation on Adult Salinity Tolerance in the Freshwater-Invading Copepod Eurytemora Affinis. Physiological and Biochemical Zoology, 76 (3), 296–301. https://doi.org/10.1086/375433
  • Medda, S., Fadda, A., Dessena, L., & Mulas, M. (2021). Quantification of Total Phenols, Tannins, Anthocyanins Content in Myrtus communis L. and Antioxidant Activity Evaluation in Function of Plant Development Stages and Altitude of Origin Site. Agronomy, 11(6), 1059. https://doi.org/10.3390/agronomy11061059
  • Miliauskas, G., Venskutonis, P.R., & Van Beek, T.A. (2004). Screening of Radical Scavenging Activity of Some Medicinal and Aromatic Plant Extracts. Food Chemistry, 85, 231–237. https://doi.org/10.1016/j.foodchem.2003.05.007
  • Mine, A., Özkan, G., & Güray, Ç.G. (2009). A Mediterranean Myrtus communis L. (Myrtle). In: Plants and Culture: Seeds of the Cultural Heritage of Europe, Morel JP and Mercuri AM (ed.). EDIPUGLIA Bari; 159–168.
  • Ozcan, M.M., Erel, O., & Herken, E.E. (2009). Antioxidant activity, phenolic content, and peroxide value of essential oil and extracts of some medicinal and aromatic plants used as condiments and herbal teas in Turkey. Journal of Medicinal Food, 12(1), 198-202. https://doi.org/10.1089/jmf.2008.0062
  • Pillaiyar, T., Manickam, M., & Namasivayam, V. (2017). Skin whitening agents: Medicinal chemistry perspective of tyrosinase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry, 32, 403–425. https://doi.org/10.1080/14756366.2016.1256882
  • Raoof, M., Khaleghi, M., Siasar, N., Mohannadalizadeh, S., Haghani, J., & Amanpour, S. (2019). Antimicrobial activity of methanolic extracts of Myrtus communis L. and Eucalyptus galbie and their combination with calcium hydroxide powder against Enterococcus faecalis. Journal of Dentistry, 20(3), 195–202. https://doi.org/10.30476/DENTJODS.2019.44898
  • Sargin, S.A. (2021). Plants used against obesity in Turkish folk medicine: A review. Journal of Ethnopharmacology, 270, 113841. https://doi.org/10.1016/j.jep.2021.113841
  • Sen, A., Kurkçuoglu, M., Yıldırım, A., Dogan, A., Bitis, L., & Baser, K.H.C. (2020). Chemical and biological profiles of essential oil from different parts of Myrtus communis L. subsp. communis from Turkey. Agriculturae Conspectus Scientificus, 85(1), 71-78.
  • Serce, S., Ercisli, S., Sengul, M., Gunduz, K., & Orhan, E. (2010). Antioxidant activities and fatty acid composition of wild grown myrtle (Myrtus communis L.) fruits. Pharmacognosy Magazine, 6(21), 9-12. https://doi.org/10.4103/0973-1296.59960
  • Snoussi, A., Essaidi, I., Koubaier, H.B.H., Zrelli, H., Alsafari, I., Živoslav, T., Mihailovic, J., Khan, M., El Omri, A., Veličković, T.C., & Bouzouita, N., 2021. Drying methodology effect on the phenolic content, antioxidant activity of Myrtus communis L. leaves ethanol extracts and soybean oil oxidative stability. BMC Chemistry, 15(1), 1 11. https://doi.org/10.1186/s13065-021-00753-2
  • Tangyu, M., Muller, J., Bolten, C.J., & Wittmann, C. (2019). Fermentation of plant-based milk alternatives for improved flavour and nutritional value. Applied Microbiology and Biotechnology, 103, 9263–9275. https://doi.org/10.1007/s00253-019-10175-9
  • Tretiakova, I., Blaesius D, Maxia L., Wesselborg, S., Schulze-Osthoff, K., Cinalt, J., Michaleis, M., & Werz, O. (2008). Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mito-chondrial pathway involving caspase-9. Apoptosis, 13, 119–131. https://doi.org/10.1007/s10495-007-0150-0
  • Tuberoso, C.I.G., Rosa, A., Bifulco, E., Melis, M.P., Atzeri, A., Pirisi, F.M., & Dessì, M.A. (2010). Chemical composition and antioxidant activities of Myrtus communis L. berries extracts. Food Chemistry, 123(4), 1242 1251. https://doi.org/10.1016/j.foodchem.2010.05.094
  • Tumen, I., Senol, F.S., & Orhan, I.E. (2012). Inhibitory potential of the leaves and berries of Myrtus communis L.(myrtle) against enzymes linked to neurodegenerative diseases and their antioxidant actions. International Journal of Food Sciences and Nutrition, 63(4), 387-392. https://doi.org/10.3109/09637486.2011.629178
  • Tuzimski, T., Petruczynik, A., Szultka-Młyńska, M., Sugajski, M., & Buszewski, B. (2022). Isoquinoline Alkaloid Contents in Macleaya cordata Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition. Molecules, 27(11), 3606. https://doi.org/10.3390/molecules27113606
  • Tuzlacı, E., & Bulut, G.E. (2007). Turkish folk medicinal plants, part VII:Ezine (Çanakkale) Journal of Faculty of Pharmacy of Istanbul University, 39, 39-51.
  • Tuzlacı, E., & Sadıkoglu, E. (2007). Turkish folk medicinal plants, part VI: Koçarli (Aydin). Journal of Faculty of Pharmacy of Istanbul University, 39, 25-37.
  • Uba, A.I., Zengin, G., Montesano, D., Cakilcioglu, U., Selvi, S., Ulusan, M.D., Caprioli, G., Sagratini, G., Angeloni, S., Jugreet, S., Hasan, M.M., & Mahoomodally, M.F. (2022). Antioxidant and Enzyme Inhibitory Properties, and HPLC–MS/MS Profiles of Different Extracts of Arabis carduchorum Boiss: An Endemic Plant to Turkey. Applied Sciences, 12(13), 6561. https://doi.org/10.3390/app12136561
  • Uysal, S., Gevrenova, R., Sinan, K.I., Bayarslan, A.U., Altunoglu, Y.C., Zheleva-Dimitrova, D., Ak, G., Baloglu, M.C., Etienne, O.K., Loıbine, D., Mahoomodally, M.F., & Zengin, G. (2021). New perspectives into the chemical characterization of Sida acuta Burm. f. extracts with respect to its anti-cancer, antioxidant and enzyme inhibitory effects. Process Biochemistry, 105, 91-101. https://doi.org/10.1016/j.procbio.2021.03.028
  • Uysal, S., Zengin, G., Locatelli, M., Bahadori, M.B., Mocan, A., Bellagamba, G., De Luca, E., Mollica, A., & Aktumsek, A. (2017). Cytotoxic and enzyme inhibitory potential of two Potentilla species (P. speciosa L. and P. reptans Willd.) and their chemical composition. Frontiers in Pharmacology, 8, 290. https://doi.org/10.3389/fphar.2017.00290
  • Wang, H., Liu, T., & Huang, D. (2013). Starch Hydrolase Inhibitors from Edible Plants. Advances in Food and Nutrition Research, 70, 103–136. https://doi.org/10.1016/B978-0-12-416555-7.00003-5
  • Wannes, W.A., Mhamdi, B., Sriti, J., Jemia, M.B., Ouchikh, O., Hamdaoui, G., Kchouk, M.E., & Marzouk, B. (2010). Antioxidant activities of the essential oils and methanol extracts from myrtle (Myrtus communis var. italica L.) leaf, stem and flower. Food and Chemical Toxicology, 48(5), 1362-1370. https://doi.org/10.1016/j.fct.2010.03.002 Wannes, W.A., & Marzouk, B. (2016). Characterization of myrtle seed (Myrtus communis var. baetica) as a source of lipids, phenolics, and antioxidant activities. Journal of Food and Drug Analysis, 24(2), 316–323. https://doi.org/10.1016/j.jfda.2015.11.001
  • Yaghoobi, M., Sanikhani, M., Samimi, Z., & Kheiry, A. (2022). Selection of a suitable solvent for bioactive compounds extraction of myrtle (Myrtus communis L.) leaves using ultrasonic waves. Journal of Food Processing and Preservation, 46(3), e16357. https://doi.org/10.1111/jfpp.16357

Assessment of antioxidant and enzyme inhibition properties of Myrtus communis L. leaves

Year 2023, Volume: 10 Issue: 2, 166 - 174, 16.06.2023
https://doi.org/10.21448/ijsm.1106464

Abstract

This study investigated the antioxidant and enzyme inhibitory properties of Myrtus communis leaves. Three different solvents including methanol, 50%-methanol, and water were used to extract of M. communis. In addition, total bioactive compounds were evaluated by using total phenolic and total flavonoid content assays. In antioxidant assays, water extract displayed the highest antioxidant potential. The MeOH extract demonstrated the highest inhibitory effect against AChE (4.38 mg GALAE/g), BChE (1.58 mg GALAE/g), α-amylase (0.56 mmol ACE/g), and tyrosinase (132.20 mg KAE/g). The M. communis leaves extract could be used as a promising raw material source in food and medicine industries.

References

  • Abdulhadi, S.M., Shami, A.M., & Saleh, M.M. (2020). Antibacterial effect, Antioxidant potential and total phenolic content of polyphenol extracts of Myrtus communis leaves. Plant Archives, 20(2), 286-291.
  • Alkaltham, M.S., Salamatullah, A.M., Özcan, M.M., Uslu, N., Hayat, K., & Mohamed Ahmed, I.A. (2021). Influence of different drying methods on antioxidant activity, total phenol, and phenolic compounds of myrtle (Myrtus communis L.) fruits. Journal of Food Processing and Preservation, 45(4), e15308. https://doi.org/10.1111/jfpp.15308
  • Amensour, M., Bouhdid, S., Fernández-López, J., Idaomar, M., Senhaji, N.S., & Abrini, J. (2010). Antibacterial activity of extracts of Myrtus communis against food-borne pathogenic and spoilage bacteria. International Journal of Food Properties, 13(6), 1215–1224. https://doi.org/10.1080/10942910903013399
  • Chryssavgi, G., Vassiliki, P., Athanasios, M., Kibouris, T., & Michael, K. (2008). Essential oil composition of Pistacia lentiscus L. and Myrtus communis L.: evaluation of antioxidant capacity of methanolic extracts. Food Chemistry, 107(3), 1120 1130. https://doi.org/10.1016/j.foodchem.2007.09.036
  • Chu, S.C. & Chen, C. (2006). Effects of origins and fermentation time on the antioxidant activities of kombucha. Food Chemistry, 98(3), 502–507. https://doi.org/10.1016/j. foodchem.2005.05.080
  • D’Urso, G., Sarais, G., Lai, C., Pizza, C., & Montoro, P. (2017). LC-MS based metabolomics study of different parts of myrtle berry from Sardinia (Italy). Journal of Berry Research, 7(3), 217-229. https://doi.org/10.3233/JBR-170158
  • Engwa, G.A. (2018). Free Radicals and the Role of Plant Phytochemicals as Antioxidants Against Oxidative Stress-Related Diseases. in: Phytochemicals - Source of Antioxidants and Role in Disease Prevention. https://doi.org/10.5772/intechopen.76719
  • Fan, L.Y., & Chiu, M.J. (2014). Combotherapy and current concepts as well as future strategies for the treatment of Alzheimer’s disease. Neuropsychiatric Disease and Treatment, 10, 439–451. https://doi.org/10.2147/NDT.S45143
  • Hennia, A., Miguel, M.G., & Nemmiche, S. (2018). Antioxidant activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. extracts: A brief review. Medicines, 5(3), 89. https://doi.org/10.3390/medicines5030089 Hur, S.J., Lee, S.Y., Kim, Y.C., Choi, I., & Kim, G.B. (2014). Effect of fermentation on the antioxidant activity in plant-based foods. Food Chemistry, 160, 346–356. https://doi.org/10.1016/j.foodchem.2014.03.112
  • Ibrahim, F., Fouad, R., El-Hallouty, S., Hendawy, S.F., Omer, E. A., & Mohammed, R.S. (2021). Egyptian Myrtus communis L. Essential oil Potential role as in vitro Antioxidant, Cytotoxic and α-amylase Inhibitor. Egyptian Journal of Chemistry, 64(6), 3005-3017. https://doi.org/10.21608/EJCHEM.2021.57354.3245
  • Kamboj, V.P. (2000). Herbal medicine. Current Science, 78(1), 35 39. https://www.jstor.org/stable/24103844
  • Kumar, S., & Pandey, A.K. (2013). Chemistry and biological activities of flavonoids: an overview. The Scientific World Journal, 2013, 162750. https://doi.org/10.1155/2013/162750
  • Lee, C.E., & Petersen, C.H. (2003). Effects of Developmental Acclimation on Adult Salinity Tolerance in the Freshwater-Invading Copepod Eurytemora Affinis. Physiological and Biochemical Zoology, 76 (3), 296–301. https://doi.org/10.1086/375433
  • Medda, S., Fadda, A., Dessena, L., & Mulas, M. (2021). Quantification of Total Phenols, Tannins, Anthocyanins Content in Myrtus communis L. and Antioxidant Activity Evaluation in Function of Plant Development Stages and Altitude of Origin Site. Agronomy, 11(6), 1059. https://doi.org/10.3390/agronomy11061059
  • Miliauskas, G., Venskutonis, P.R., & Van Beek, T.A. (2004). Screening of Radical Scavenging Activity of Some Medicinal and Aromatic Plant Extracts. Food Chemistry, 85, 231–237. https://doi.org/10.1016/j.foodchem.2003.05.007
  • Mine, A., Özkan, G., & Güray, Ç.G. (2009). A Mediterranean Myrtus communis L. (Myrtle). In: Plants and Culture: Seeds of the Cultural Heritage of Europe, Morel JP and Mercuri AM (ed.). EDIPUGLIA Bari; 159–168.
  • Ozcan, M.M., Erel, O., & Herken, E.E. (2009). Antioxidant activity, phenolic content, and peroxide value of essential oil and extracts of some medicinal and aromatic plants used as condiments and herbal teas in Turkey. Journal of Medicinal Food, 12(1), 198-202. https://doi.org/10.1089/jmf.2008.0062
  • Pillaiyar, T., Manickam, M., & Namasivayam, V. (2017). Skin whitening agents: Medicinal chemistry perspective of tyrosinase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry, 32, 403–425. https://doi.org/10.1080/14756366.2016.1256882
  • Raoof, M., Khaleghi, M., Siasar, N., Mohannadalizadeh, S., Haghani, J., & Amanpour, S. (2019). Antimicrobial activity of methanolic extracts of Myrtus communis L. and Eucalyptus galbie and their combination with calcium hydroxide powder against Enterococcus faecalis. Journal of Dentistry, 20(3), 195–202. https://doi.org/10.30476/DENTJODS.2019.44898
  • Sargin, S.A. (2021). Plants used against obesity in Turkish folk medicine: A review. Journal of Ethnopharmacology, 270, 113841. https://doi.org/10.1016/j.jep.2021.113841
  • Sen, A., Kurkçuoglu, M., Yıldırım, A., Dogan, A., Bitis, L., & Baser, K.H.C. (2020). Chemical and biological profiles of essential oil from different parts of Myrtus communis L. subsp. communis from Turkey. Agriculturae Conspectus Scientificus, 85(1), 71-78.
  • Serce, S., Ercisli, S., Sengul, M., Gunduz, K., & Orhan, E. (2010). Antioxidant activities and fatty acid composition of wild grown myrtle (Myrtus communis L.) fruits. Pharmacognosy Magazine, 6(21), 9-12. https://doi.org/10.4103/0973-1296.59960
  • Snoussi, A., Essaidi, I., Koubaier, H.B.H., Zrelli, H., Alsafari, I., Živoslav, T., Mihailovic, J., Khan, M., El Omri, A., Veličković, T.C., & Bouzouita, N., 2021. Drying methodology effect on the phenolic content, antioxidant activity of Myrtus communis L. leaves ethanol extracts and soybean oil oxidative stability. BMC Chemistry, 15(1), 1 11. https://doi.org/10.1186/s13065-021-00753-2
  • Tangyu, M., Muller, J., Bolten, C.J., & Wittmann, C. (2019). Fermentation of plant-based milk alternatives for improved flavour and nutritional value. Applied Microbiology and Biotechnology, 103, 9263–9275. https://doi.org/10.1007/s00253-019-10175-9
  • Tretiakova, I., Blaesius D, Maxia L., Wesselborg, S., Schulze-Osthoff, K., Cinalt, J., Michaleis, M., & Werz, O. (2008). Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mito-chondrial pathway involving caspase-9. Apoptosis, 13, 119–131. https://doi.org/10.1007/s10495-007-0150-0
  • Tuberoso, C.I.G., Rosa, A., Bifulco, E., Melis, M.P., Atzeri, A., Pirisi, F.M., & Dessì, M.A. (2010). Chemical composition and antioxidant activities of Myrtus communis L. berries extracts. Food Chemistry, 123(4), 1242 1251. https://doi.org/10.1016/j.foodchem.2010.05.094
  • Tumen, I., Senol, F.S., & Orhan, I.E. (2012). Inhibitory potential of the leaves and berries of Myrtus communis L.(myrtle) against enzymes linked to neurodegenerative diseases and their antioxidant actions. International Journal of Food Sciences and Nutrition, 63(4), 387-392. https://doi.org/10.3109/09637486.2011.629178
  • Tuzimski, T., Petruczynik, A., Szultka-Młyńska, M., Sugajski, M., & Buszewski, B. (2022). Isoquinoline Alkaloid Contents in Macleaya cordata Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition. Molecules, 27(11), 3606. https://doi.org/10.3390/molecules27113606
  • Tuzlacı, E., & Bulut, G.E. (2007). Turkish folk medicinal plants, part VII:Ezine (Çanakkale) Journal of Faculty of Pharmacy of Istanbul University, 39, 39-51.
  • Tuzlacı, E., & Sadıkoglu, E. (2007). Turkish folk medicinal plants, part VI: Koçarli (Aydin). Journal of Faculty of Pharmacy of Istanbul University, 39, 25-37.
  • Uba, A.I., Zengin, G., Montesano, D., Cakilcioglu, U., Selvi, S., Ulusan, M.D., Caprioli, G., Sagratini, G., Angeloni, S., Jugreet, S., Hasan, M.M., & Mahoomodally, M.F. (2022). Antioxidant and Enzyme Inhibitory Properties, and HPLC–MS/MS Profiles of Different Extracts of Arabis carduchorum Boiss: An Endemic Plant to Turkey. Applied Sciences, 12(13), 6561. https://doi.org/10.3390/app12136561
  • Uysal, S., Gevrenova, R., Sinan, K.I., Bayarslan, A.U., Altunoglu, Y.C., Zheleva-Dimitrova, D., Ak, G., Baloglu, M.C., Etienne, O.K., Loıbine, D., Mahoomodally, M.F., & Zengin, G. (2021). New perspectives into the chemical characterization of Sida acuta Burm. f. extracts with respect to its anti-cancer, antioxidant and enzyme inhibitory effects. Process Biochemistry, 105, 91-101. https://doi.org/10.1016/j.procbio.2021.03.028
  • Uysal, S., Zengin, G., Locatelli, M., Bahadori, M.B., Mocan, A., Bellagamba, G., De Luca, E., Mollica, A., & Aktumsek, A. (2017). Cytotoxic and enzyme inhibitory potential of two Potentilla species (P. speciosa L. and P. reptans Willd.) and their chemical composition. Frontiers in Pharmacology, 8, 290. https://doi.org/10.3389/fphar.2017.00290
  • Wang, H., Liu, T., & Huang, D. (2013). Starch Hydrolase Inhibitors from Edible Plants. Advances in Food and Nutrition Research, 70, 103–136. https://doi.org/10.1016/B978-0-12-416555-7.00003-5
  • Wannes, W.A., Mhamdi, B., Sriti, J., Jemia, M.B., Ouchikh, O., Hamdaoui, G., Kchouk, M.E., & Marzouk, B. (2010). Antioxidant activities of the essential oils and methanol extracts from myrtle (Myrtus communis var. italica L.) leaf, stem and flower. Food and Chemical Toxicology, 48(5), 1362-1370. https://doi.org/10.1016/j.fct.2010.03.002 Wannes, W.A., & Marzouk, B. (2016). Characterization of myrtle seed (Myrtus communis var. baetica) as a source of lipids, phenolics, and antioxidant activities. Journal of Food and Drug Analysis, 24(2), 316–323. https://doi.org/10.1016/j.jfda.2015.11.001
  • Yaghoobi, M., Sanikhani, M., Samimi, Z., & Kheiry, A. (2022). Selection of a suitable solvent for bioactive compounds extraction of myrtle (Myrtus communis L.) leaves using ultrasonic waves. Journal of Food Processing and Preservation, 46(3), e16357. https://doi.org/10.1111/jfpp.16357
There are 36 citations in total.

Details

Primary Language English
Subjects Structural Biology
Journal Section Articles
Authors

Sengul Uysal 0000-0003-4562-1719

Kouadio Ibrahime Sinan This is me 0000-0002-6168-5707

Gokhan Zengin 0000-0001-6548-7823

Early Pub Date May 26, 2023
Publication Date June 16, 2023
Submission Date April 20, 2022
Published in Issue Year 2023 Volume: 10 Issue: 2

Cite

APA Uysal, S., Sinan, K. I., & Zengin, G. (2023). Assessment of antioxidant and enzyme inhibition properties of Myrtus communis L. leaves. International Journal of Secondary Metabolite, 10(2), 166-174. https://doi.org/10.21448/ijsm.1106464
International Journal of Secondary Metabolite

e-ISSN: 2148-6905