Review on antibiotics residues and their extraction and detection methods in highly consumed foodstuffs

Year 2023, Volume: 10 Issue: 3, 405 - 413, 27.08.2023

Md Amzad Hossain , Salem Said Jaroof Al Touby Ahmed Abu Sham Waleed Khalid Hilal Al Rajhi Ali Attia Abedlnaeem Attia Salem

https://doi.org/10.21448/ijsm.1247832

Abstract

Antibiotics have been widely used in the food industry, and their utilization has increased tremendously. Foodstuffs sometimes comprise excessive amounts of antibiotic residues due to a lack of awareness and misuse of these valuable drugs. The misuse of antibiotics in foods has led to the growth of bacterial resistance. Over the past century, the increasing use and abuse of antibiotics in food animals have directed to the prevalent transmission of bacterial and genetic resistance between animals and humans. Antibiotic residue from foods is considered a significant contaminant that threatens human health worldwide. Awareness and training on the application of antibiotics among farmers and drug sellers can rationalize the use of antibiotics in food animals. The Government of Oman should create and firmly implement application guidelines to regulate the use and prevent the misuse of antibiotics in foodstuffs sectors. This review aims to explore the current status of antibiotic residue in foodstuffs, and their detection, separation, and identification technologies in use. The review also highlights alternative ways to fight bacterial resistance.

Keywords

Foodstuffs, Antibiotic usage, Extraction, Identification and quantification, Antibiotic resistance, Oman

Supporting Institution

NA

Project Number

NA

Thanks

No fund received

References

• Al-Bahry, S., Mahmoud, I., Al-Khaif, A., Elshafe, A., & Al-Harthy, A. (2009). Viability of multiple antibiotic resistant bacteria in distribution lines of treated sewage efuent used for irrigation. Water Science Technology, 60(11), 236–245.
• Al-Bahry, S., Mahmoud, I., & Al-Musharaf, S. (2019). Antibiotic resistant bacteria used as bioindicators of environmental pollution produced by tertiary treated sewage efuent. WIT Trans Ecology Environment, 164, 313–321
• Al-Bahry, S.N., Al-Hinai, J.A., Mahmoud, I.Y., & Al-Musharaf, S.K. (2019). Opportunistic and microbial pathogens in municipal water distribution systems. APCBEE Proceeding, 5, 339–343.
• Al Salah, D.M.M., Laffite, A., & Pote, J. (2019). Occurrence of bacterial markers and antibiotic resistance genes in Sub-Saharan rivers receiving animal farm wastewaters. Science Report, 9, 14847.
• Anand, U., Reddy, B., Singh, V.K., Singh, A.K., Kesari, K.K., & Tripathi, P. (2012). Potential environmental and human health risks are caused by antibiotic-resistant bacteria (ARB), antibiotic resistance genes (ARGs), and emerging contaminants (E.C.s) from municipal solid waste (MSW) landfills. Antibiotics, 10, 374.
• Bai, H., He, L.Y., Wu, D.L., Gao, F.Z., Zhang, M., & Zou, H.Y. (2021). Spread of airborne antibiotic resistance from animal farms to the environment: dispersal pattern and exposure risk. Environmental International, 158, 106927.
• Betina, V. (1973). Bioautography in paper and thin-layer chromatography and its scope in the antibiotic field. Journal of Chromatography, A 78, 41–51.
• Brandt, K.K., Am'ezquita, A., & Backhaus, T. (2015). Ecotoxicological assessment of antibiotics: a call for improved consideration of microorganisms. Environment International, 85, 189–205.
• Brewer, N.S., & Hellinger, W.C. (1999). The monobactams. Mayo Clin Proc., 66(11), 1152-1157. https://doi.org/10.1016/s0025-6196(12)65797-8
• Chadwick, D., & Goode, J. (1997). Antibiotic resistance: origins, evolution, selection and spread. John Wiley, Sons; U.K.
• Chandler, C.I.R. (2019). Current accounts of antimicrobial resistance: stabilisation, individualisation and antibiotics as infrastructure. Palgrave Communication, 5, 53.
• Chen, J., Ying, G.G., & Deng, W.J. (2019). antibiotic residues in food: extraction, analysis, and human health concerns. Journal of Agriculture and Food Chemistry, 67, 7569–7586.
• Chowdhury, S., Ghosh, S., Aleem, M.A., Parveen, S., Islam, M.A., & Rashid, M.M. (2021). Antibiotic usage and resistance in food animal production: what have we learned from Bangladesh. Antibiotics (Basel), 10, 1032.
• Department of Agriculture & Dairy (2008) part III: Reference of dairy cattle health and management practices in the United States, 2007. Fort Collins (C.O.): USDA, Animal and plant health inspection service, Veterinary Services, National Animal Health Monitoring System; September 2008.
• Department of Agriculture (U.S.). Feedlot (2000) part III: health management and biosecurity in U.S. feedlots, 1999. Fort Collins (CO): USDA, Animal and Plant Health Inspection Service,
• Farouk, F., Azzazy, H.M.E., & Niessen, W.M.A. (2015). Challenges in the Determination of Aminoglycoside Antibiotics, a Review. Analytical Chimistry Acta, 890, 21–43.
• FDA -US Food and Drug Administration. (2017). summary report on antimicrobials sold or distributed for use in food producing animals; 2017. https://www.fda.gov/downloads/ForIndustry/UserFees/AnimalDrugUserFeeActADUFA/UCM588085.pdf
• Zotchev, B.S. (2003). Polyene macrolide antibiotics and their applications in human therapy Current Medicinal Chemistry 10(3), https://dx.doi.org/10.2174/0929867033368448
• Heesemann, J. (1993). Mechanisms of resistance to beta-lactam antibiotics. Infection, 21(1): S4-9.
• Henry, R.J. (1943). The mode of action of sulfonamides. Bacteriology Review, 7(4), 175-262.
• Holten, K.B., & Onusko, E.M. (2000). Appropriate prescribing of oral beta-lactam antibiotics. American Fam Physician, 62(3), 611-620.
• Jammoul, A., & El Darra, N. (2019). Evaluation of antibiotics residues in chicken meat samples in Lebanon. Antibiotics, 8, 69.
• Jiang, H., Zhou, R., Yang, Y., Chen, B., Cheng, Z., Zhang, M., Li, J., Zhang, G., & Zou, S. (2018). Characterizing the antibiotic resistance genes in a river catchment: Influence of anthropogenic activities. Journal of Environmental Sciences, 69, 125–132.
• Kahne, D., Leimkuhle, C., Lu, W., & Walsh, C. (2005). Glycopeptide and lipoglycopeptide antibiotics. Chemical Review, 105(2), 425-448.
• Kang, H.K., & Park, Y. (2005). Glycopeptide antibiotics: Structure and mechanism of action. Journal of Bacteriological and Virological, 45(2), 67-78.
• Karkman, A., Do, T.T., Walsh, F., & Virta, M.P.J. (2018). Antibiotic-resistance genes in waste water. Trends Microbiology, 26, 220–228.
• Kaza, S., Yao, L., Bhada-Tata, P., & VanWoerden, F. (2023). What a Waste 2.0: A Global snapshot of solid waste management to 2050;World Bank Publications: Washington, DC, USA, 2018; Available online: https://elibrary.worldbank.org/doi/abs/10.1596/978-1-4648-1329-0 (accessed on 23 January 2023).
• Kneebone, J., Tsang, P.C.W., & Towson, D.H. (2010). Rapid antibiotic screening tests detect antibiotic residues in powdered milk products. Journal of Dairy Sciences, 93, 3961–3964.
• Kumar, A., & Pal, D. (2018). Antibiotic resistance and wastewater: correlation, impact and critical human health challenges. Journal of Environmental Chemistry Engineering, 6, 52–58.
• Larsson, D.G.J. (2014). Antibiotics in the environment. Upsala Journal of Medical Sciences, 119, 108–112.
• Levy, S.B. (2007). Antibiotic resistance: An Ecological Imbalance, in Ciba Foundation Symposium 207-Antibiotic resistance: origins, evolution, selection and spread. Chadwick D.J., Goode J. John Wiley & Sons, Ltd. (ed): Chichester, UK, 1:1-14.
• Liu, J.K., Zheng, H., & Lu, J.L. (2017). Recent progress and perspective of trace antibiotics detection in aquatic environment by surface-enhanced Raman spectroscopy. Trends in Environmental Analytical Chemistry, 16, 16–23.
• Li, T., Wang, C., Xu, Z., & Chakraborty, A. (2020). A coupled method of on-line solid phase extraction with the uhplc-ms/ms for detection of sulfonamides antibiotics residues in aquaculture. Chemosphere, 254, 126765.
• Livermore, D.M., Warner, M., Mushtaq, S., Doumith, M., Zhang, J., & Woodford, N. (2011). What remains against carbapenem-resistant Enterobacteriaceae? Evaluation of chloramphenicol, ciprofloxacin, colistin, fosfomycin, minocycline, nitrofurantoin, temocillin and tigecycline. International Journal Antimicrobiol Agents, 37, 415-419.
• Majdinasab, M., Mishra, R.K., Tang, X., & Marty, J.L. (2020). Detection of antibiotics in food: new achievements in the development of biosensors. TrAC Trends Analytical Chemistry, 127, 115883.
• Markina, N.E., Markin, A.V., Weber, K., Popp, P., Cialla-May, D. (2020). Liquid-liquid extraction-assisted SERS base determination of sulfamethoxazole in spiked human urine. Analytica Chimica Acta, 1109, 61–68.
• McEwen, S.A., & Fedorka-Cray, P.J. (2002). Antimicrobial use and resistance in animals. Clinical Infectious Diseases, 34, 93–106.
• Menkem, Z.E., Ngangom, B.L., Tamunjoh, S.S.A., & Boyom, F.F. (2019). Antibiotic residues in food animals: public health concern. Acta Ecological Sciences, 39, 411–415.
• Phillips, I. (2003). Does the use of antibiotics in food animals pose a risk to human health, a critical review of published data. Journal of Antimicrobial Chemotherphy, 53, 28–52.
• Raymond, M.J., Wohrle, R.D., & Call, D.R. (2006). Assessment and promotion of judicious antibiotic use on dairy farms in Washington State. J Dairy Sci, 89, 3228-3240.
• Rizzo, L., Della, S.A., Fiorentino, A., & Puma, G.L. (2014). Disinfection of urban wastewater by solar driven and U.V. lamp–TiO2 photocatalysis: Effect on a multi drug resistant Escherichia coli strain. Water Research, 53, 145–152.
• Ovung, A., & Bhattacharyya J. Sulfonamide drugs. (2021) structure, antibacterial property, toxicity, and biophysical interactions. Biophysics Review, 13(2), 259 272. https://doi.org/10.1007/s12551-021-00795-9
• Schaenzer, A.J., & Wright, G.D. (2020). Antibiotic resistance by enzymatic modification of antibiotic targets. Rends in Molecular Medicine, 26, 768–782.
• Sanchez, A.R., Rogers, R.S., & Sheridan, P.J. (2004). Tetracycline and other tetracycline-derivative staining of the teeth and oral cavity. International Journal of Dermatology, 43(10),709-715.
• Senyuva, H., Ozden, T., & Sarica, D.Y. (2000). High-performance liquid chromatographic determination of oxytetracycline residue in cured meat products. Turkish Journal of Chemistry, 24, 395–400.
• Sykes, R.B., & Bonner, D.P. (1985). Discovery and development of the monobactams. Clinical Infection Diseases, 7(4), S579-S593.
• Sykes, R.B., Cimarusti, C.M., Bonner, D.P., Bush, K., Floyd, D.M., Georgopapadakou, N.H., Koster, W.H., Liu, W.C., Parker, W.L. Principe, P.A., Rathnum, M.L., Slusarchyk, W.A., Trejo, W.H., & Wells, J.S. (2015). Monocyclic β-lactam antibiotics produced by bacteria. Nature, 291, 489-491.
• Tripathi, V., & Tripathi, P. (2017). Antibiotic resistance genes: an emerging environmental pollutant. in perspectives in environmental toxicology. Environmental Science and Engineering, Kesari, K., Ed.; Springer: Cham, Switzerland, p.183–201.
• Van Boeckel, T.P., Glennon, E.E., Chen, D., Gilbert, M., Robinson, T.P., Grenfell, B.T., Levin, S.A., Sebastian Bonhoeffer, S., & Laxminarayan, R. (2017). Reducing antimicrobial use in food animals. Science, 357(6358), 1350–1352. https://doi.org/10.1126/science.aao1495
• Vannuffel, P., & Cocito, C. (1996). Mechanism of action of streptogramins and macrolides. Drugs, 51(1), 20-30.
• Veterinary Services, National Animal Health Monitoring System; December 2000.
• Walsh, C. (2003). Antibiotics: actions, origins, resistance. 1st Ed. ASM Press, Washington, DC. p.345.
• Wang, J.Y., An, X.L., Huang, F.Y., & Su, J.Q. (2020). Antibiotic resistome in a landfill leachate treatment plant and effluent-receiving river. Chemosphere, 1, 125207.
• Witte, W. (1998). Medical consequences of antibiotic use in agriculture. Science, 279, 996–997.
• Xu, G., Dong, X., Hou, L., Wang, X., Liu, L., Ma, H., & Zhao, R.S. (2020). Room-temperature synthesis of flower-shaped covalent organic frameworks for solid-phase extraction of quinolone antibiotics. Analytical Chimical Acta, 1126, 82–90.
• Zhang, S., Abbas, M., Rehman, M.U., Huang, Y., Zhou, R., Gong, S., Yang, H., Chen, S., Wang, M., & Cheng, A. (2020). Dissemination of antimicrobial resistance genes (ARGs) via integrons in Escherichia coli: A risk to human health. Environmental Pollution, 266, 115260.