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Antioxidant activity, phytochemical screening and GC-MS profile of Abies marocana Trab.

Year 2024, Volume: 11 Issue: 1, 121 - 133, 05.02.2024
https://doi.org/10.21448/ijsm.1372709

Abstract

The aim of this research was to explore the chemical composition and antioxidant activities of etheric extracts of Abies marocana. A Soxhlet apparatus was used to extract bioactive molecules from the various parts of the plant. Furthermore, the levels of antioxidant compounds were quantified, while the Gas chromatography was utilized to determine the chemical constituents of the extracted molecules. The extracts were evaluated for their antioxidant properties using the DPPH radical scavenging method and the total antioxidant capacity test. The levels of polyphenols varied across different parts of the plant, ranging from 2.474 ± 0.029 mg.g-1 DM in needles to 4.207 ± 0.008 mg.g-1 DM in twigs. Flavonoids were most abundant in needles 0.140 ± 0.001 mg.g-1 DM and least abundant in cones 0.069 ± 0.007 mg.g-1 DM. Tannins had the highest concentration in twigs 2.608 ± 0.114 mg.g-1 DM, followed by cones 1.948 ± 0.037 mg.g-1 DM and needles 1.512 ± 0.09 mg.g-1 DM. A chromatographic analysis revealed that 56 components were in the samples, with terpene compounds being the most abundant in the different organs. In terms of antioxidant activity, the extract derived from twigs exhibited the strongest antioxidant capacity 49.377 ± 0.371 mg EAA.g-1 DM, followed by cones 35.129 ± 0.084 mg EAA.g-1 DM and needles 13.663 ± 0.084 mg EAA.g-1 DM. Alternatively, the IC50 values for the three organs were found to be in the range of 3844 to 5047.67 µg.mL-1. The results highlight the potential phytopharmaceutical value of A. marocana due to the presence of diverse phyto-components.

References

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Antioxidant activity, phytochemical screening and GC-MS profile of Abies marocana Trab.

Year 2024, Volume: 11 Issue: 1, 121 - 133, 05.02.2024
https://doi.org/10.21448/ijsm.1372709

Abstract

The aim of this research was to explore the chemical composition and antioxidant activities of etheric extracts of Abies marocana. A Soxhlet apparatus was used to extract bioactive molecules from the various parts of the plant. Furthermore, the levels of antioxidant compounds were quantified, while the Gas chromatography was utilized to determine the chemical constituents of the extracted molecules. The extracts were evaluated for their antioxidant properties using the DPPH radical scavenging method and the total antioxidant capacity test. The levels of polyphenols varied across different parts of the plant, ranging from 2.474 ± 0.029 mg.g-1 DM in needles to 4.207 ± 0.008 mg.g-1 DM in twigs. Flavonoids were most abundant in needles 0.140 ± 0.001 mg.g-1 DM and least abundant in cones 0.069 ± 0.007 mg.g-1 DM. Tannins had the highest concentration in twigs 2.608 ± 0.114 mg.g-1 DM, followed by cones 1.948 ± 0.037 mg.g-1 DM and needles 1.512 ± 0.09 mg.g-1 DM. A chromatographic analysis revealed that 56 components were in the samples, with terpene compounds being the most abundant in the different organs. In terms of antioxidant activity, the extract derived from twigs exhibited the strongest antioxidant capacity 49.377 ± 0.371 mg EAA.g-1 DM, followed by cones 35.129 ± 0.084 mg EAA.g-1 DM and needles 13.663 ± 0.084 mg EAA.g-1 DM. Alternatively, the IC50 values for the three organs were found to be in the range of 3844 to 5047.67 µg.mL-1. The results highlight the potential phytopharmaceutical value of A. marocana due to the presence of diverse phyto-components.

References

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  • Aouji, M., Imtara, H., Rkhaila, A., Bouhaddioui, B., Alahdab, A., Parvez, M. K., Saleh Alzahrani, M., Aicha Lrhorfi, L., & Bengueddour, R. (2023). Nutritional Composition, Fatty Acids Profile, Mineral Content, Antioxidant Activity and Acute Toxicity of the Flesh of Helix aspersa Müller. Molecules, 28(17), 6323. https://doi.org/10.3390/molecules28176323
  • Aryal, S., Baniya, M.K., Danekhu, K., Kunwar, P., Gurung, R., & Koirala, N. (2019). Total Phenolic Content, Flavonoid Content, and Antioxidant Potential of Wild Vegetables from Western Nepal. Plants, 8, 96-107. https://doi.org/10.3390/plants8040096
  • Banjare, J., Salunke, M., Indapurkar, K., Ghate, U., & Bhalerao, S. (2017). Estimation of serum malondialdehyde as a marker of lipid peroxidation in medical students undergoing examination-induced psychological stress. Journal of the Scientific Society, 44, 137-139. https://www.jscisociety.com/text.asp?2017/44/3/137/225497
  • Barrero, F.A., Sanchez, F.J., Alvarez-Manzaneda, J.E., Muñoz, M., & Haïdour, A. (1992). Diterpenoids and cyclolanostanolides from Abies marocana. Phytochemistry, 31(2), 615-620. https://doi.org/10.1016/0031-9422(92)90046-S
  • Batool, R., Khan, M.R., Sajid, M., Ali, S., & Zahra, Z. (2019). Estimation of phytochemical constituents and in vitro antioxidant potencies of Brachychiton populneus (Schott & Endl) R. Br. BMC Chem., 13, 32-46. https://doi.org/10.1186/s13065-019-0549-z
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  • Bazdi, B., Oller-López, J.L., Cuerva, J.M., Oltra, J.E., & Mansour, A.I. (2006). Composition of the Essential Oil from the Seeds of Abies marocana. Journal of Essential Oil Research, 18(2), 160-161. https://doi.org/10.1080/10412905.2006.9699053
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  • Bhattacharya, T., Dutta, S., Akter, R., Rahman, M.H., Karthika, C., Nagaswarupa, H.P., Murthy, H.C.A., Fratila, O., Brata, R., & Bungau, S. (2021). Role of Phytonutrients in Nutrigenetics and Nutrigenomics Perspective in Curing Breast Cancer. Biomolecules, 11, 1176. https://doi.org/10.3390/biom11081176
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  • Boadi, N.O., Badu, M., Kortei, N.K., Saah, S.A., Annor, B., Mensah, M.B., Okyere, H., & Fiebor, A. (2021). Nutritional composition and antioxidant properties of three varieties of carrot (Daucus carota). Scientific African, 12, e00801. https://doi.org/10.1016/j.sciaf.2021.e00801
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  • Bukhanko, N., Attard, T., Arshadi, M., Eriksson, D., Budarin, V., Hunt, A.J., Geladi, P., Bergsten, U., & Clark, J. (2020). Extraction of cones, branches, needles and bark from Norway spruce (Picea abies) by supercritical carbon dioxide and Soxhlet extractions techniques. Industrial Crops and Products, 145, 112096. https://doi.org/10.1016/j.indcrop.2020.112096
  • Cheok, C., Chin, N., Yusof, Y., Talib, R., & Law, C. (2013). Optimization of total monomeric anthocyanin (TMA) and total phenolic content (TPC) extractions from mangosteen (Garcinia mangostana Linn.) hull using ultrasonic treatments. Industrial crops and Products, 50, 1-7. https://doi.org/10.1016/j.indcrop.2013.07.024
  • Chukwuma, F.I., Nkwocha, C.C., Ezeanyika, L.U.S., & Ogugua, V.N. (2020). Phytochemical Investigation and In vitro Antioxidant Potency of Root Bark of Brenania brieyi Fractions. Tropical Journal of Natural Product Research, 4(11), 970 975. https://doi.org/10.26538/tjnpr/v4i11.21
  • El Hazzat, N., Iraqi, R., & Bouseta, A. (2015). GC-MS and GCFID-O identification of volatile compounds in green olives of the Moroccan variety & Picholine" effect of geographical origin. International Journal of Biological and Chemical Sciences, 9(4), 2219-2233. https://doi.org/10.4314/ijbcs. v9i4.40
  • Farjon, A., & Rushforth, K.D. (1989). A classification of Abies Miller (Pinaceae). Notes from the Royal Botanic Garden, Edinburgh., 46(1), 59-79.
  • Gehin, A., Guyon, C., & Nicod, L. Glyphosate induced antioxydant imbalance in HacaT: The protective effect of vitamin C and E. Environmental Toxicology and Pharmacology, 22, 27-34. https://doi.org/10.1016/j.etap.2005.11.003
  • Gorinstein, S., Yamamoto, K., Katrich, E., Leontowicz, H., Lojek, A., Leontowicz, M., Ciz, M., Goshev, I., Shalev, U., & Trakhtenberg S. (2003). Antioxidative properties of Jaffa sweeties and grapefruit and their influence on lipid metabolism and plasma antioxidative potential in rats. Bioscience Biotechnology Biochemical, 67, 907 910. https://doi.org/10.1271/bbb.67.907
  • Gupta, D., & Kumar, M. (2017). Evaluation of in vitro antimicrobial potential and GC–MS analysis of Camellia sinensis and Terminalia arjuna. Biotechnology Reports, 13, 19-25. https://doi.org/10.1016/j.btre.2016.11.002
  • Hagerma, A.E. (2002). Tannin Handbook. 2éme edition. Miami University. Oxford, USA, 116.
  • Hatami, T., Emami, S.A., Miraghaee, S.S., & Mojarrab, M. (2014). Total phenolic contents and antioxidant activities of different extracts and fractions from the aerial parts of Artemisia biennis Willd. Iranian Journal of Pharmaceutical Research, 13(2), 551. https://doi.org/10.22037/ijpr.2014.1518
  • Herode, S.S., Hadolin, M., Škerget, M., & Knez, Z. (2003). Solvent extraction study of antioxidants from balm (Melissa officinalis I.) leaves. Food Chemistry, 80, 275-282. https://doi.org/10.1016/S0308-8146(02)00382-5
  • Hmamouchi, M. (1999). Les plantes médicinales et aromatiques marocaines: utilisation, biologie, écologie, chimie, pharmacologie, toxicologie, lexiques. Bibliographie du patrimoine culturel immatériel.
  • Ishola, I.O, Ikuomola, B.O., & Adeyemi, O.O. (2018). Protective role of Spondias mombin leaf and Cola acuminata seed extracts against scopolamine-induced cognitive dysfunction. Alexandria J Med., 54, 27-39. https://doi.org/10.1016/j.ajme.2016.08.001
  • Khan, R.A., Khan, M.R., & Sahreen, S. (2012). Assessment of flavonoids contents and in vitro antioxidant activity of Launaea procumbens. Chem Central J., 6, 43.
  • Kuluvar., G., Mahmood, R., Mohamed, R., Ahamed, K., Babu, P., & Venkatarangaiah, K. (2009). Wound healing activity of Clerodendrum infortunatum Linn. Root extracts, Int J of Biom and Pharm Sci., 3(1), 21-25.
  • Lamaison, J.L., & Carnat, A. (1990). Teneur en principaux flavonoides des fleurs et des feuilles de Crataegus monogyna Jacq. et de Crataegus laevigata (Poiret) DC. (Rosacea). Pharmaceutica Acta Helvetia, 65(11), 315-320.
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There are 53 citations in total.

Details

Primary Language English
Subjects Plant Biotechnology
Journal Section Articles
Authors

Malak Zırarı 0009-0006-8685-4796

Marouane Aoujı 0000-0002-5884-0016

Meryem Zouarhi This is me 0000-0002-2123-0476

Ahmed Dermaj This is me 0009-0002-9537-8809

Hamid Erramli This is me 0000-0001-5367-4787

Driss Hmouni This is me 0000-0001-7598-6204

Nouredine El Mejdoub This is me 0000-0003-1225-5900

Publication Date February 5, 2024
Submission Date October 7, 2023
Published in Issue Year 2024 Volume: 11 Issue: 1

Cite

APA Zırarı, M., Aoujı, M., Zouarhi, M., Dermaj, A., et al. (2024). Antioxidant activity, phytochemical screening and GC-MS profile of Abies marocana Trab. International Journal of Secondary Metabolite, 11(1), 121-133. https://doi.org/10.21448/ijsm.1372709
International Journal of Secondary Metabolite

e-ISSN: 2148-6905