Anticancer Effect of Food Supplements on Saos-2 Osteosarcoma Cell

Year 2020, Volume: 1 Issue: 1, 18 - 24, 30.04.2020

Kağan Ağan Roshanak Zarringhalami Aydan Fülden Ağan , Mustafa Yaşar

Abstract

Objective: Nowadays medicinal plants have been considered as complementary medicine in cancer treatment by many researchers. Osteosarcoma, one of the most common malignant tumors, which is more common at a young age; It is one of the most common types of cancer that occur in mesenchymal bone-forming cells and affect the musculoskeletal system. Today instead of cancer drugs due to their numerous side effects that can suppress or prevent cancer treatment, food supplement products that contain plant extracts may be preferred. In this study, the anticancer effects of five different food supplements were investigated on osteosarcoma Saos-2 cancer cell line. 

Material-Method: Application doses were as 1000, 2000, 3000, 4000, 5000, 6000 µg/ml and IC50 values were calculated by creating two working groups of 24 and 48 hours. 

Results: Extracts of five different herbal product showed cytotoxic effect on Saos-2 cancer cell line due to their mixture of medicinal plants, however REGULIN® showed the most cytotoxic effect among them.

Conclusion: It was determined that REGULIN® used in the remember regeneration therapy method (RTM), had the most anticancer effect in each of the 24 and 48 hour application groups. Cytotoxic effect of these food products on other cancer cell lines and their use in the pharmaceutical and health industries is recommended in future studies.

Keywords

Osteosarcoma, Anticancer, Saos-2

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