Kronik Obstrüktif Akciğer Hastalığı Olan Hastalarda Ceviz Yaprağı Çayı Kullanımının Alevlenme Sıklığını ve Yaşam Kalitesini Azaltmaya Etkisi

Year 2025, Volume: 6 Issue: 1, 1 - 10, 25.04.2025

Sultan Zortul

https://doi.org/10.53811/ijtcmr.1601121

Abstract

Effect of Use of Walnut Leaf Tea on Reduction of Exacerbation Frequency and Quality of Life in Patients with Chronic Obstructive Lung Disease

Abstract

Objective: The purpose of this study is to investigate the effect of tea prepared with walnut leaves used by patients with chronic obstructive pulmonary disease (COPD) in addition to their own medical treatments on exacerbation frequency, dyspnea score and life comfort.
Materials and Methods: The structure of this study was planned as a quasi-experimental research. It was conducted in accordance with the principles of the Declaration of Helsinki. 80 patients who were diagnosed with COPD and accepted to participate in the study at the outpatient clinics of the Chest Diseases Department of Atatürk University Faculty of Medicine were divided into two groups consisting of patients selected with the cluster sampling method. The first group consisted of 40 randomly selected patients who consumed walnut leaf tea in addition to their COPD treatment, while the second group consisted of 40 patients who only received their own medical treatment and did not use any complementary medicine method. When the participants came to the study, their complete blood count values were seen, GOLD staging was performed according to spirometry values, mMRC (Modified Medical Research Council Dyspnea Scale), CAT (COPD Assessment Test), Katz daily living activities scale (ADL) were applied, and a combined COPD assessment was made. Both groups were followed up for 6-month periods and the follow-up was terminated after 3 interviews.
Results: 80 volunteers participated in the study. The average age of the patients was 67.1±7 years and 57.5 % of them were male, 42.5 % were smokers and 56.3 % were COPD stage 2. At the end of the year, the rate of hospital admissions in participants who did not drink walnut leaf tea was 85% while the rate of hospital admissions in participants who drank tea was 17.5% and the difference between them was significant p=0.00. The rate of patients who were planned to change treatment due to exacerbation was 7.5% in participants who drank tea and 40% in participants who did not drink it and the difference between them was significant p=0.00. At the end of the year, there was a significant difference in terms of the decrease in CAT score between patients who drank tea and those who did not drink it, p=0.007.
Conclusion: It was determined that among COPD patients, those who consumed walnut leaf tea in addition to their treatment had fewer exacerbations, fewer hospital admissions and fewer hospital stays, and their comfort of life was positively affected by this situation.

Keywords

COPD , walnut leaf , quality of life , dyspnea

References

• Salık MA, Çakmakçı S. Ceviz (Juglans regia L.) Yaprağı ve Yeşil Kabuğu: Fonksiyonel Özellikleri, Sağlığa Yararları ve Gıdalarda Kullanım Potansiyeli. Akademik Gıda. Mart 2023;21(1):90-100.
• Pereira JA, Oliveira I, Sousa A, et.al. Walnut (Juglans regia L.) leaves: Phenolic compounds, antibacterial activity and antioxidant potential of different cultivars. Food and chemical toxicology 2007; 45(11):2287-2295.
• Vieira V, Pereira C, Pires TC, et.al. Phenolic profile, antioxidant and antibacterial properties of Juglans regia L.(walnut) leaves from the Northeast of Portugal. Industrial Crops and Products 2019;134:347-355.
• Tang YT, Li Y, Chu P, et.al. Molecular biological mechanism of action in cancer therapies: Juglone and its derivatives, the future of development. Biomedicine & Pharmacotherapy (2022); 148, 112785.
• Ünal A. Acil Serviste Koah Alevlenme Olgularında Kısa Dönem Prognoz Tahmininde Ottawa Koah Risk Skalası (Ocrs) ile Decaf Skorunun Karşılaştırılması. 2021. PhD Thesis. Dokuz Eylul Universitesi (Turkey). Erişim tarihi: 09 Kasım 2024.
• Yeh GY, Wayne PM, Litrownik D, et.al.Tai chi mind-body exercise in patients with COPD: study protocol for a randomized controlled trial. 2014; Trials 15, 337 (2014).
• Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS medicine. 2006; 3(11):e442.
• Patel N. An update on COPD prevention, diagnosis, and management: The 2024 GOLD Report. The Nurse Practitioner.2024; 49(6):p 29-36.
• Yohannes AM, Alexopoulos GS, Depression and anxiety in patients with COPD. European respiratory review. 2014; 23(133):345-349.
• Williams CM,Dyspnea. The Cancer Journal. 2006; 12(5):365-373.erişim tarihi: 10.10.2024
• Kütmeç YC.Hastanede Yatan Kronik Obstrüktif Akciğer Hastalığı Olan Bireylerde Dispne Şiddeti ve Genel Konfor Düzeyi Arasındaki İlişkinin Belirlenmesi. Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi. 2020; 13(4), 222-230.
• Özkaraca F, Yılmaz CK. KOAH Hastalarında Dispne Şiddetinin ve Genel İyi Oluş Düzeylerinin İncelenmesi. İzmir Göğüs Hastanesi Dergisi. 2024; 38(1):29-40.erişim tarihi:10.12.2024
• Tepetam FM. Uzmanlık Tezi.“Stabil Kronik Obstriktif Akciğer Hastalığında Dispneyi Değerlendiren Yöntemlerin ve BODE İndeksinin Fonksiyonel Parametrelerle Karşılaştırılması”. Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi Göğüs Hastalıkları Kliniği, Tez Yöneticisi.Doç. Dr. Benan Çağlayan. İstanbul- 2007. Erişim tarihi: 15.12.2024
• Yapucu ÜG, Kara D, Erbağcı A. Dispne yakınması olan hastalarda farklı dispne ölçeklerinin karşılaştırılması. Dokuz Eylül Üniversitesi Hemşirelik Yüksekokulu Elektronik Dergisi.2012; 5, ( 2 ), pp.65 - 71. erişim tarihi:13.12.2024
• Yapıcı S, Kıvanç M. Ceviz Yaprak Ekstrelerinin Antioksidan, Antimikrobiyel Ve Antibiyofilm Aktivitesi. GIDA. April 2023;48(2):405-421.
• Lobach EY, Tokhiriyon B, Poznyakovsky V. et.al. New phytocomplex for chronic obstructive pulmonary disease: Development and clinical evidence of anti-inflammatory effect. Journal of Advanced Pharmacy Education and Research. 2023; 13(3), 102-108.
• Safari S, Davoodi P, Soltani A, et.al. M. Curcumin effects on chronic obstructive pulmonary disease: A systematic review. Health Science Reports. 2023; 6(3):e1145.
• Ahmed MS, Neyaz A, Aslami AN.Health-related quality of life of chronic obstructive pulmonary disease patients. Results from a community based cross-sectional study in Aligarh, Uttar Pradesh, India. Lung India. 2016; 33(2):148-153.
• Demirel Y. Kronik Obstrüktif Akciğer Hastalığı olan bireylerde diyete eklenen curcuminin dispne ve yaşam kalitesi üzerine etkisi. Sağlık Bilimleri Enstitüsü, Hemşirelik Ana Bilim Dalı, Yüksek Lisans Tezi. Kars, Kafkas Üniversitesi, 2018. Erişim tarihi: 10.10.2024.
• Wang J, Li J, Yu X, Xie Y. Acupuncture Therapy for Functional Effects and Quality of Life in COPD Patients: A Systematic Review and Meta‐Analysis. BioMed research international. 2018;(1):3026726.
• Arslan C, Ünsar S. Kronik Obstrüktif Akciğer Hastalarinda Dispne Algisi Ve Yaşam Kalitesinin Değerlendirilmesi. Anadolu Hemşirelik Ve Sağlık Bilimleri Dergisi. 2021; 24(1):42-50.
• Van Manen JG, Bindels PJ, Dekker FW, et.al. The influence of COPD on health-related quality of life independent of the influence of comorbidity. Journal of clinical epidemiology. 2003; 56(12):1177-1184.