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Pharmacological activities of Borassus flabellifer L. extracts and isolated compounds

Year 2021, Volume: 5 Issue: 2, 23 - 31, 15.12.2021

Abstract

OBJECTIVE: The purpose of this systematic review work is to evaluate, summarize, and document the scientific findings of the pharmacological activities of this plant species.

MATERIALS AND METHODS: The major electronic databases (Web of Science, Scopus, ScienceDirect, and PubMed) have been employed to identify related publications published from 1900 to July 2021. In this review, only reported pharmacological activities-related publications were considered to extract the data.

Results: Various parts of this plant species are used to treat various disorders in traditional medicines including various pulmonary complaints, diabetes, and heartburn. Further, compounds such as borassoside A to F, nicotinamide, and uracil have been isolated from various parts of B. flabellifer. Clinical, in vivo, and in vitro pharmacological scientific evidence is currently available, and various parts of B. flabellifer showed antiarthritic, anticancer, antipyretic, hypersensitivity, and immunomodulatory activities. Flower showed the greatest number of pharmacological activities. Hitherto, seven bioactive compounds have been identified from B. flabellifer. Only, some uses of B. flabellifer in traditional medicine have scientific evidence at the moment.

Conclusion: This review article summarized the available scientific evidence based on pharmacological activities of B. flabellifer. The importance and benefits of this plant species are known for a limited group of people and the significance of B. flabellifer should be understood to sustain this invaluable resource.

Supporting Institution

Not Applicable

Project Number

Not Applicable

Thanks

This work received no funding. The authors are grateful to their family members for their support to deliver this work.

References

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Year 2021, Volume: 5 Issue: 2, 23 - 31, 15.12.2021

Abstract

Project Number

Not Applicable

References

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  • 2. Blombery A, Rodd T. 1992. Palms of the World. Angus and Robertson Publication
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  • 4. Pramod HJ, Yadav AV, Raje VN, Madhuri M, Ganesh W. Antioxidant activity of Borassus flabellifer (Linn.) fruits. Asian J Pharm Tech. 2013; 3 (1): 16-19.
  • 5. World agroforestry center. 2021. Available from: http://www.worldagroforestry.org/. Accessed on 02.04.2021
  • 6. Uphof JC. Dictionary of economic plants. H.R. Engelmann, J. Cramer. 1959. Available from: https://books.google.lk/books?id=iYMQtAEACAAJ. Accessed on 02.04.2021
  • 7. Digital Compendium of Forestry Species of Cambodia. 2008. Available from: http://www.digitalspecies.blogspot.com. Accessed on 02.04.2021
  • 8. Arunachalam K, Saravanan S, Parimelazhagan T. Nutritional analysis and antioxidant activity of palmyrah (Borassus flabellifer L.) seed embryo for potential use as food source. Food Science and Biotechnology, 2011; 20 (1): 143–149. https://doi.org/10.1007/s10068-011-0020-y
  • 9. Khare C. Borassus flabellifer Linn. In: Khare C. (eds) Indian Medicinal Plants. Springer, New York, NY. 2007. https://doi.org/10.1007/978-0-387-70638-2_232
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  • 12. Vivekanandarajah S, Rajamanoharan PRS, Munday M, Heinrich M. Plants used to treat diabetes in Sri Lankan Siddha Medicine – An ethnopharmacological review of historical and modern sources. Journal of Ethnopharmacology. 2016; 198: 531–599. https://doi.org/10.1016/j.jep.2016.07.053
  • 13. Vivekanandarajah S, Rajamanoharan P, Munday M, Heinrich M. Plants currently used to treat diabetes in Sri Lankan Siddha Medicine – an ethnobotanical survey in the Eastern Province. Presented at the World Congress Integrative Medicine & Health 2017: part three, Springer Nature, Berlin, Germany. 2017; 333. https://doi.org/10.1186/s12906-017-1784-2
  • 14. Vivekanandarajah S, Rajamanoharan PRS, Heinrich M. Siddha Medicine in Eastern Sri Lanka Today–Continuity and Change in the Treatment of Diabetes. Front. Pharmacol. 2018; 9: 1022. https://doi.org/10.3389/fphar.2018.01022
  • 15. Shamala D, Arseculeratne SN, Pathmanathan R, McKenzie IFC, Pang T. Suppression of cell-mediated immunity following oral feeding of mice with palmyrah (Borassus flabellifer L) flour. Aust. J. Exp. Biol. Med. Sci. 1985; 63: 371–379.
  • 16. Vengaiah PC, Ravindrababu D, Murthy GN, Prasad KR. Jaggery from Palmyrah palm (Borassus flabellifer L.)- present status and scope. Indian J Tradit Knowledge, 12 (4), 714-717.
  • 17. Kaladhar DSVGK, Siva Kishore N. (2010). Antimicrobial studies, biochemical and image analysis in Mirabilis jalapa. International Journal of Pharmacy & Technology. 2013; 2 (3): 683-693.
  • 18. Rajamanoharan, P., Vivekanandarajah, S. The role of honey in pediatric treatments in Sri Lankan Siddha Medicine. Uludag Bee Journal. 2021; 21: 83–90. https://doi.org/10.31467/uluaricilik.851567
  • 19. Vivekanandarajah S. Antidiabetic plants used by Sri Lankan Tamils. Jaffna Science Association Newsletter. 2021; 28 (3): 3.
  • 20. Vivekanandarajah S. நீரிழிவைக் கட்டுப்படுத்த இலங்கைத் தமிழர்கள் உபயோகித்த தாவரங்கள்- பகுதி: 1 (Plants used by Sri Lankan Tamils to manage diabetes – Part: 1). Valampurii Newspaper2021.
  • 21. Vivekanandarajah S. நீரிழிவைக் கட்டுப்படுத்த இலங்கைத் தமிழர்கள் உபயோகித்த தாவரங்கள்- பகுதி: 2 (Plants used by Sri Lankan Tamils to manage diabetes – Part: 2). Valampurii Newspaper2021.
  • 22. Vivekanandarajah S. நீரிழிவைக் கட்டுப்படுத்த இலங்கைத் தமிழர்கள் உபயோகித்த தாவரங்கள்- பகுதி: 3 (Plants used by Sri Lankan Tamils to manage diabetes – Part: 3). Valampurii Newspaper. 2021.
  • 23. Vivekanandarajah S. Plants historically used by Sri Lankan Tamils to treat diabetes. Presented at The International Dr. Safiye Ali Multidisciplinary Studies Congress in Health Sciences, İzmir, Turkey. 2021.
  • 24. Vivekanandarajah S. Plants used to treat diabetes in Sri Lankan Siddha Medicine (Ph.D. Thesis). University College London, London, UK. 2018.
  • 25. Vivekanandarajah S. Plants historically used to treat diabetes in Sri Lankan Siddha Medicine. Presented at the International Seminar & Exhibition on Phytopharmaceuticals: Emerging Challenges and Opportunities, Ooty, India. 2017.
  • 26. Vivekanandarajah S. Plants with Anti-Diabetes Mellitus Properties, 591, Appian Subramoniam, CRC Press (Taylor & Francis Group), Boca Raton (FL, USA). Journal of Ethnopharmacology. 2016; 191: 19–20. https://doi.org/10.1016/J.JEP.2016.06.031
  • 27. Reshma MV, Jacob J, Syamnath VL, Habeeba VP, Dileep Kumar BS, Lankalapalli RS. First report on isolation of 2,3,4-trihydroxy-5-methyl acetophenone from palmyra palm (Borassus flabellifer Linn.) syrup, its antioxidant and antimicrobial properties. Food Chemistry. 2017; 228: 491–496. https://doi.org/10.1016/j.foodchem.2017.02.043
  • 28. Revesz L, Hiestand P, Vecchia LLa, Naef R, Naegeli HU, Oberer L, Roth HJ. Isolation and synthesis of a novel immunosuppressive 17or-substituted dammarane from the flour of the palmyrah palm. Bioorganic & Medicinal Chemistry Letters. 1999; 9: 1521–1526.
  • 29. Yoshikawa MY, Fengming XU, Orikawa TM, Ongpiriyadacha YP. Medicinal Flowers . XII. 1) New Spirostane-Type Steroid Saponins with Antidiabetogenic Activity from Borassus flabellifer. 2007; 55 (2): 308–316.
  • 30. Jamkhande PG, Suryawanshi VA, Wattamwar AS, Barde SR. In vitro anthelmintic efficacy of Borassus flabellifer Linn. (Palmae) against Pheretima posthuma. Asian Pacific Journal of Tropical Disease, 2014; 4 (S1). https://doi.org/10.1016/S2222-1808(14)60439-4
  • 31. Paschapur MS, Patil MB, Kumar R, Patil SR. Evaluation of anti-inflammatory activity of ethanolic extract of Borassus flabellifer L. male flowers (inflorescences) in experimental animals. Journal of Medicinal Plants Research, 2009a; 3 (2): 049–054.
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There are 63 citations in total.

Details

Primary Language English
Journal Section Reviews
Authors

Vinujan Shanmugalingam 0000-0002-9208-4090

Saravanan Vivekanandarajah Sathasivampillai 0000-0002-5938-0509

Srithayalan Srivijeindran 0000-0001-7276-8607

Project Number Not Applicable
Publication Date December 15, 2021
Submission Date July 12, 2021
Published in Issue Year 2021 Volume: 5 Issue: 2

Cite

APA Shanmugalingam, V., Vivekanandarajah Sathasivampillai, S., & Srivijeindran, S. (2021). Pharmacological activities of Borassus flabellifer L. extracts and isolated compounds. International Journal of Innovative Research and Reviews, 5(2), 23-31.