-

Abstract

Phyllodes tumours are rare and account for 0.4% of breast tumours. The majority of them tend to be less than 5 cm in size with giant tumours larger than 10 cm being about 20 % of these cases. Here, a 75-year-old woman patient diagnosed by malignant phyllodes tumour was submitted. The patient was hospitalized with a diagnosis of rapidly enlarging bulk in the left breast. After physicial and radiological examination the patient underwent excisional biopsy was performed. On gross examination, there was a 17 cm in size, nodüler outer surface, sectional face was observed in solid tumors and nodular apperance. The case diagnosed as malignant phyllodes tumor has been presented in company with the literature as a result of the histopathologic and immunohistochemical analysis

Keywords

• -

MEMENİN DEV MALİGN FİLLOİDES TÜMÖRÜ

Öz

Filloides tümörler nadirdir ve  primer meme tümörlerinin % o.4ünü oluşturur. Çoğunluğu 5 cmden küçük olmakla beraber %20sinde tümör boyutu 10 cmden  büyüktür. Bu yazıda, malign filloides tümör tanısı alan 75 yaşındaki kadın hasta sunulmuştur. Olgu, sol memede hızlı büyüyen kitle nedeni ile hastanemize başvurdu. Hastanın   fizik muayene, ultrasonografik ve mamografik incelemesinden sonra  kitle eksize edildi. Makroskopik incelemesinde 17 cm boyutunda nodüler dış yüzeyli, kesit yüzü solid, nodüler görünümlü tümör izlendi. Histopatolojik ve immünohistokimyasal inceleme sonucu  malign filloides tümör tanısı alan olgu literatür eşliğinde sunuldu.

Anahtar Kelimeler

• Dev, Filloides Tümör, Malign, Meme

References

1. Ben Hassouna J, Damak T, Gamoudi A, Chargul R, Khomsi F, Mahjoub S, et al. Phyllodes Tumours of the Breast: A Case Series of 106 Patients. American Journal of Surgery. 2006; 192(2): 141-147
2. Parker SJ, Harries SA. Phyllodes Tumours. Postgrad Med J. 2001;77(909):428-435.
3. Sugie T, Takeuchi E, Kunishima F, Yotsumoto F, Kono Y. Case of ductalcarcinoma with squamous differentiation in malignant phyllodes tumor. Breast Cancer. 2007;14(3):32732.
4. Schnitt SJ, Collins LC. Philadelphia, PA: Wolters Kluwer, Lippincott Williams & Wilkins. Biopsy Interpretation of the Breast, 2009; 154–81.
5. Tan PH, Tse G, Lee A, Simpson J, Hanby A. Fibroepithelial tumours. In Lakhani SR, Ellis IO, Schnitt SJ, Tan PH, van de Vijver MJ, eds. WHO Classification of Tumours of the Breast.Lyon: IARC Press 2012; 142-147.
6. Sugie T, Takeuchi E, Kunishima F, Yotsumoto F, Kono Y. A case of ductal carcinoma with squamous differentiation in malignant phyllodes tumor. Breast Cancer. 2007;14:327-32.
7. Moffat CJ, Pinder SE, Dixon AR, Elston CW, Blamey RW, Ellis IO. Phyllodes tumours of the breast: a clinicopathological review of thirty-two cases. Histopathology. 1995;27(3):205218.
8. Dupont WD, Page DL, Parl FF, et al. Long term risk of breast cancer in women with fibroadenoma. N Engl J Med. 1994; 331(1):10-15.

9. Daya D, Trus T, D’Souza TJ, Minuk T, Yemen B. Hamartoma of the breast, an underrecognized breast lesion. A clinicopathologic and radiographic study of 25 cases. Am J Clin Pathol. 1995;103(6):685-689.
10. Machado NO. Recurrent Giant Phyllodes Tumour of the Breast Pathological Considerations and Management Approach for Recurrence and Metastasis. Surgical Science. 2012;3(4)..