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YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*

Year 2000, Volume: 31 Issue: 4, 0 - , 20.08.2014

Abstract

Background and Design.- An increase in oxidative stress may contribute to the development of oxidative protein damage in aging. In the present study, we investigated the relation between aging and oxidative protein damage parameters such as plasma protein carbonyl and protein thiol, as well as oxidative stress parameters such as total thiol, nonprotein thiol and lipid hydroperoxides in the plasma samples of young adult, adult and young old individuals.

Results.- Protein carbonyl and lipid hydroperoxide levels were significantly increased in aging individuals. On the other hand, total thiol and protein thiol levels were significantly decreased in aging individuals. Protein carbonyl, protein thiol, and lipid hydroperoxide levels were significantly correlated with age.

Conclusion.- The result of this study suggests that increased plasma protein carbonyl levels and decreased plasma protein thiol levels in aging individuals may reflect the oxidative protein damage.

* Anahtar Kelimeler : Oksidatif protein hasarı, Karbonil, Tiol

* Key Words : Oxidative protein damage, Carbonyl, Thiol

 

Year 2000, Volume: 31 Issue: 4, 0 - , 20.08.2014

Abstract

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Details

Primary Language Turkish
Journal Section Araştırmalar
Authors

Ufuk Çakatay This is me

Ayşegül Telci This is me

İlker Yılmaz This is me

Tülay Akçay This is me

Ahmet Sivas This is me

Publication Date August 20, 2014
Published in Issue Year 2000 Volume: 31 Issue: 4

Cite

APA Çakatay, U., Telci, A., Yılmaz, İ., Akçay, T., et al. (2014). YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*. Cerrahpaşa Tıp Dergisi, 31(4).
AMA Çakatay U, Telci A, Yılmaz İ, Akçay T, Sivas A. YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*. Cerrahpaşa Tıp Dergisi. August 2014;31(4).
Chicago Çakatay, Ufuk, Ayşegül Telci, İlker Yılmaz, Tülay Akçay, and Ahmet Sivas. “YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*”. Cerrahpaşa Tıp Dergisi 31, no. 4 (August 2014).
EndNote Çakatay U, Telci A, Yılmaz İ, Akçay T, Sivas A (August 1, 2014) YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*. Cerrahpaşa Tıp Dergisi 31 4
IEEE U. Çakatay, A. Telci, İ. Yılmaz, T. Akçay, and A. Sivas, “YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*”, Cerrahpaşa Tıp Dergisi, vol. 31, no. 4, 2014.
ISNAD Çakatay, Ufuk et al. “YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*”. Cerrahpaşa Tıp Dergisi 31/4 (August 2014).
JAMA Çakatay U, Telci A, Yılmaz İ, Akçay T, Sivas A. YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*. Cerrahpaşa Tıp Dergisi. 2014;31.
MLA Çakatay, Ufuk et al. “YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*”. Cerrahpaşa Tıp Dergisi, vol. 31, no. 4, 2014.
Vancouver Çakatay U, Telci A, Yılmaz İ, Akçay T, Sivas A. YAŞLANMANIN PLAZMA OKSİDATİF PROTEİN HASARINA ETKİSİ*. Cerrahpaşa Tıp Dergisi. 2014;31(4).