Abstract
Basal cell carcinoma(BCC) is the most common skin tumor however it is very rare in childhood and usually associated with genetic syndromes. BCC can be sporadic very rarely in this age group but mostly there is a predisposing factor such as nevus sebaceous. In this case, 13 year-old girl developed a pigmented nodular lesion in the nevus sebaceous and referred to our clinic for excisional biopsy. The tumor was excised and pigmented basal cell carcinoma was diagnosed according to the pathology report. BCC in the childs may be overlooked due to the low prevalence so predisposing factors such as nevus sebaceous should be kept in mind and morphological changes seen in the lesion should be confirmed by biopsy
References
- 1- Cribier B, Scrivener Y, Grosshans E. Tumors arising in nevus sebaceus: A study of 596 cases. J Am Acad Dermatol 2000;42(2):263-8.
- 2- Crowson AN. Basal cell carcinoma: biology, morphology and clinical implications; Mod Pathol 2006;19(2):127-47.
- 3- De la Luz Orozco-Covarrubias M, Tamayo-Sanchez L, Duran-McKinster C, et al. Malignant cutaneous tumors in children: twenty years of experience at a large pediatric hospital. J Am Acad Dermatol 1994;30(2):243-9.
- 4- Dunkin CS, Abouzeid M, Sarangapani K, Malignant transformation in congenital sebaceous naevi in childhood; J R Coll Surg Edinb 2001;46(5):303-6.
- 5- Gaitan-Gaona F, Said MC, Galvan-Linares A. Rapidly growing pigmented tumor on a scalp nevus sebaceous of a pediatric patient: Observation or excision, Dermatol Online J 2014;20(7).
- Çocukta sebase nevüs zemininde gelişen BCC
- 6- Kuvat SV, Gülcin Z, Keklik B, et al. Basal cell carcinoma in a child. J Skin Cancer 2011; doi:10.1155/2011/752901.
- 7- LeSueur BW, Silvis NG, Hansen RC, Basal cell carcinoma in children, report of 3 cases; Arch Dermatol 2000;136(3):370-2.
- 8- Ramachandran S, Fryer AA, Lovatt T, et al. The rate of increase in the numbers of primary sporadic basal cell carcinomas during follow up is associated with age at Şrst presentation. Carcinogenesis 2002; 23(12):2051-4.
- 9- Santibanez-Gallerani A, Marshall D, Duarte AM, et al. Should nevus sebaceus of Jadassohn in children be excised? A study of 757 cases, and literature review J Craniofac Surg. 2003;14(5):658-60.
- 10- Varan, A. Gököz, C. Akyüz et al. Primary malignant
- skin tumors in children: etiology, treatment and
- prognosis. Pediatr Int 2005;47(6):653-7.
Abstract
Bazal hücreli karsinom en sık görülen deri tümörüdür ancak çocukluk çağında oldukça nadir görülür. Çocuklarda
genellikle genetik sendromlarla birliktedir. Çok nadiren sporadik olarak da gözlenebilir ancak daha çok altta yatan bir
predispozan faktör bulunur (örneğin nevüs sebaseus gibi).
Bu çalışmada 13 yaşında nevüs sebaseus tanısıyla takip edilen hastanın lezyonunda büyüme ve koyu renkli nodül
gelişmesi üzerine bazal hücreli karsinom ön tanısıyla eksizyonu yapıldı ve patoloji sonucunda da pigmente BCC olduğu
gözlendi.
Çocukluk çağında sıklığı az olması sebebiyle gözden kaçabilecek bir lezyon olan BCC nin, genetik sendromlar dışında
kalan nevus sebaseus varlığında akılda bulundurulması gerektiği, lezyonda görülen morfolojik değişikliklerin
eksizyonel biyopsi ile doğrulanması gerektiği görüşündeyiz.
References
- 1- Cribier B, Scrivener Y, Grosshans E. Tumors arising in nevus sebaceus: A study of 596 cases. J Am Acad Dermatol 2000;42(2):263-8.
- 2- Crowson AN. Basal cell carcinoma: biology, morphology and clinical implications; Mod Pathol 2006;19(2):127-47.
- 3- De la Luz Orozco-Covarrubias M, Tamayo-Sanchez L, Duran-McKinster C, et al. Malignant cutaneous tumors in children: twenty years of experience at a large pediatric hospital. J Am Acad Dermatol 1994;30(2):243-9.
- 4- Dunkin CS, Abouzeid M, Sarangapani K, Malignant transformation in congenital sebaceous naevi in childhood; J R Coll Surg Edinb 2001;46(5):303-6.
- 5- Gaitan-Gaona F, Said MC, Galvan-Linares A. Rapidly growing pigmented tumor on a scalp nevus sebaceous of a pediatric patient: Observation or excision, Dermatol Online J 2014;20(7).
- Çocukta sebase nevüs zemininde gelişen BCC
- 6- Kuvat SV, Gülcin Z, Keklik B, et al. Basal cell carcinoma in a child. J Skin Cancer 2011; doi:10.1155/2011/752901.
- 7- LeSueur BW, Silvis NG, Hansen RC, Basal cell carcinoma in children, report of 3 cases; Arch Dermatol 2000;136(3):370-2.
- 8- Ramachandran S, Fryer AA, Lovatt T, et al. The rate of increase in the numbers of primary sporadic basal cell carcinomas during follow up is associated with age at Şrst presentation. Carcinogenesis 2002; 23(12):2051-4.
- 9- Santibanez-Gallerani A, Marshall D, Duarte AM, et al. Should nevus sebaceus of Jadassohn in children be excised? A study of 757 cases, and literature review J Craniofac Surg. 2003;14(5):658-60.
- 10- Varan, A. Gököz, C. Akyüz et al. Primary malignant
- skin tumors in children: etiology, treatment and
- prognosis. Pediatr Int 2005;47(6):653-7.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Reports |
| Authors | |
| Publication Date | March 13, 2015 |
| Submission Date | December 22, 2014 |
| Published in Issue | Year 2014 |
Cite
Contact information and address
Addressi: İ.Ü. İstanbul Tıp Fakültesi Dekanlığı, Turgut Özal Cad. 34093 Çapa, Fatih, İstanbul, TÜRKİYE
Email: itfdergisi@istanbul.edu.tr
Phone: +90 212 414 21 61