HİSTEREKTOMİ YAPILAN OLGULARDA OVER REZERVİNİN ANTİMÜLLERİAN HORMON VE ULTRASONOGRAFİ İLE DEĞERLENDİRİLMESİ

Abstract

Amaç: Bu çalışma da ooforektomi yapılmadan histerektomi uygulanan olgularda erken overyan yetmezlik riskini ortaya koymak amaçlandı.

Gereç ve Yöntem: Bu çalışmaya; 25-50 yaş arasında, daha önceden bilateral ooferektomi geçirmemiş, menopoz veya prematüre overyan yetmezliği olmayan, çeşitli endikasyonlarla histerektomi kararı alınan 28 hasta dahil edildi. Bu hastaların ameliyat öncesi ve ameliyattan 1 ay sonrası Antimüllerian hormon (AMH), over hacmi ve antral folikül sayısı (AFS) karşılaştırıldı.

Bulgular: Ameliyat sonrası bakılan AMH değerinde, overlerin hacminde ve AFS lerde istatistiksel olarak anlamlı derecede azalma saptandı (p < 0.05).

Sonuç: Histerektomi yapılan reprodüktif dönemdeki hastalarda ooferektomi operasyonu uygun endikasyonlar dahilinde yapılmalıdır ve histerektomi yapıldıktan sonra erken menopoza girebileceği öngörülerek, menopoz semptomlarının başlaması beklenmeden yakın takip ve uygun tedavi planlanmalıdır.

Keywords

• Antimüllerian Hormon (AMH)
• Antral folikül sayısı
• Histerektomi
• Over rezervi

EVALUATION OF THE EFFECTS OF HYSTERECTOMY ON OVARIAN RESERVE BY ANTIMULLERIAN HORMONE AND ULTRASONOGRAPHY

Abstract

Objective: Our study aimed to determine the risk of premature ovarian failure of patients to whom hysterectomy was performed without oophorectomy.

Materials and Methods: 28 hysterectomised patients due to various indications that met the eligibility criteria of age 25 to 50 years, had no history of bilateral oophorectomy, were not menopausal or premature ovarian failure, were included in this study. These patients’ AMH (Antimullarian hormone), ovarian volume and AFC (antral follicle count) were compared before and 1 month after surgery. Results: AMH, the volume of the ovaries and the number of antral follicles revealed a significant decrease after surgery. (p<0.05)

Conclusions: Oophorectomy performed in patients of reproductive age should be made within appropriate indications. Because hysterectomised women in reproductive period may enter early menopause, strict follow-up and appropriate treatment should be carried out without waiting for menopause symptoms

Keywords

• Anti mullerian hormone (AMH)
• Antral follicle count
• Hysterectomy
• Ovarian reserve

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