Sistemik Lupus Eritematozuslu 126 Gebenin Perinatal Sonuçları

Abstract

DOI: 10.26650/IUITFD.344912

Amaç: Sistemik lupus eritematozus (SLE) tanısı almış ve gebe olan olguların maternal ve perinatal sonuçlarının değerlendirilmesi amaçlanmıştır.

Gereç ve Yöntem: Çalışmamız 2002-2016 yılları arasında üniversitemizin perinataloji kliniğinde gebelikleri takip edilmiş 126 SLE olgusunun dosya verilerinin retrospektif olarak incelenmesiyle yapıldı. Hastaların klinik karakteristikleri, obstetrik ve perinatal sonuçları değerlendirildi.

Bulgular: Hastaların ortalama yaşı 29,1± 4,6 yıl ve nulliparite oranı %45,2 idi. Gebelik sırasında hastalığın alevlenmesi hastaların %11,1’ inde görüldü. Lupus antikoagulanı, antikardiyolipin IgG ve IgM antikorlarının pozitifliği sırasıyla; %23,8 , %18,2 ve  %18,2 olarak saptandı. Ortalama doğum haftası 37,2±3,7, ortalama doğum kilosu 2813 ±856 gr bulundu. Fetal büyüme kısıtlılığı, preterm doğum, ölü doğum, preeklampsi görülme oranları sırasıyla; %16,6 , %10,3 , %10,3 , %9,5 olarak bulundu.

Sonuç: SLE tanılı gebelik olgularının yönetiminde multidisipliner yaklaşım ile takip ve tedavinin sağlanması olumlu maternal ve fetal sonuçlar ile ilişkilidir.

Keywords

• Sistemik lupus eritematozus,perinatal,maternal,gebelik

Perinatal Outcomes Of 126 Pregnancies With Sistemic Lupus Erythematosus

Abstract

DOI: 10.26650/IUITFD.344912

Objective: To evaluate maternal and fetal outcomes in pregnant women with systemic lupus erythematosus (SLE).

Materials and Methods: This retrospective clinical study included 126 consecutive cases of pregnant women with SLE and was performed in the perinatology clinic of our university hospital. We evaluated lupus pregnancies that were followed and delivered from 2002 to 2016.

Results: The mean patient age was 29.1 ± 4.6 years, and the nulliparity rate was 45.2%. Disease flare-up occurred in 11.1% of patients. Lupus anticoagulants and anticardiolipin IgG and IgM antibodies were positive in 23.8%, 18.2%, and 18.2% patients, respectively. The mean gestational age at delivery was 37.2 ± 3.7, and the mean birth weight was 2813 ± 856 g. Fetal growth restriction, preterm delivery, stillbirth, and preeclampsia rates were 16.6%, 10.3%, 10.3%, and 9.5%, respectively.

Conclusion: A multidisciplinary approach to the care of pregnant women with SLE is mandatory for good maternal and fetal outcomes.

Keywords

• Systemic lupus erythematosus,perinatal,maternal,pregnancy

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