POTANSİYEL CANLI BÖBREK VERİCİLERİNİN REDDEDİLME NEDENLERİNİN DEĞERLENDİRİLMESİ: TEK MERKEZ DENEYİMİ

Year 2019, , 127 - 130, 16.07.2019

Serkan Feyyaz Yalın , Ergün Parmaksız Meral Meşe Zuhal Doğu Nihal Derin Çeçen Zerrin Bicik Bahçebaşı

https://doi.org/10.26650/IUITFD.2019.0015

Abstract

Amaç: Böbrek nakli diyaliz tedavisine gore son dönem böbrek yetmezlikli hastalarda daha iyi sonuçlar sağlamaktadır. Canlıdan böbrek nakli ise kadavradan böbrek nakline gore daha iyi hasta ve greft sağ kalımı sağlar. Öte yandan, uzun dönem komplikasyonlar olarak hafif proteinüri, kan basıncında artış, preeklampsi, son dönem böbrek hastalığı ve ölüm hala vericiler için önemli sorunlardır. Bu çalışmada, hastanemizdeki böbrek verici reddedilme nedenlerini değerlendirmeyi amaçladık. Gereç ve Yöntem: Verici adaylarının tıbbi bilgileri retrospektif olarak incelendi. Tarama testleri, cross match testi, doku tiplendirilmesi, rutin kardiyolojik, solunum sistemi, psikiyatrik durumlarının değerlendirilmesi ve gerekliyse kanser taraması yapıldı. Veriler ortalama±standard sapma olarak gösterildi. Bulgular: İki yüz kırkbeş birey verici adayı olarak başvurdu. Bunlardan 118’i donor olamadı. Bunların 21 tanesi tüm değerlendirmeler yapıldıktan sonra verici olmaktan vazgeçti. Kalan 97 bireyin en sık reddedilme nedenleri hipertansiyon, diyabetes mellitus-obezite, glomerular filtrasyon oranında asimetri-parankimal bozukluklar idi. Ayrıca , beş verici adayında kanser tanısı koyduk. Sonuç: Potansiyel böbrek verici adaylarının değerlendirilmesi, ileride çıkabilecek riskleri azaltmak için hayati önem taşımaktadır

Keywords

Böbrek nakli, canlı böbrek verici adayı, hipertansiyon

EVALUATING THE CAUSES FOR REJECTION OF POTENTIAL LIVE-RENAL DONORS: SINGLE CENTER EXPERIENCE

Abstract

Objective: Renal transplantation provides better outcomes for end stage renal disease patients in comparison to dialysis. Living kidney donation provides better long-term patient and graft survival compared to deceased-donor transplantations. In the long term, complications such as mild proteinuria, an increase in blood pressure, preeclampsia, end stage renal disease and mortality are the main problems for donors. In this study, we aimed to evaluate the causes of kidney donor rejections in our hospital. Material and Method: The medical files of individuals presented as donor candidates were retrospectively examined. Screening tests, cross match test, tissue typing, routine evaluation of cardiologic system, respiratory system, psychiatric condition and cancer screenings, if necessary, were performed as part of the donor candidate work-up. Data was expressed as mean±SD. Results: Two hundred and forty five individuals presented themselves as donor candidates in our hospital. Of these, 118 patients could not be donors. Of these 118 individuals, 21 potential donors were rejected donor despite completing all evaluations. The main causes for rejection of 97 individuals were hypertension, diabetes mellitus-obesity and asymmetry in glomerular filtration rate/parenchymal abnormalities. In addition, we diagnosed cancer in 5 potential donors. Conclusion: Potential kidney donor evaluation is of paramount importance in order to minimize possible risks.

Keywords

Renal transplantation, living kidney donor candidate, hypertension

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