RADIOLOGICAL FINDINGS IN X-LINKED HYPOPHOSPHATEMIA

Abstract

Radiological findings in X-linked hypophosphatemia are similar to, albeit less severe than, nutritional rickets. Loss of distinctness of the zone of provisional calcification, widening of the growth plate first in the long axis, followed by widening in the short axis, “cupping” of the metaphysis and irregularity (fraying) at the metaphyseal border are seen on X-rays of long bones. The severity of the findings can be assessed from bilateral anteroposterior X-rays of the wrists and knees using the “Rickets Severity Score” (RSS). RSS can be used at the time of diagnosis as well as for assessing response to treatment. The “Radiographic Global Impression of Change Scale” (RGI-C) is another scoring method which can be used during follow-up of patients.

Keywords

• X-ray,rickets,scoring

X’E BAĞLI HİPOFOSFATEMİDE RADYOLOJİK BULGULAR

Abstract

X’e bağlı hipofosfatemide radyolojik olarak, daha hafif olmakla birlikte, nütrisyonel raşitizme benzer bulgular izlenir. Grafilerde uzun kemiklerin kemikleşme bölgesinde opak hattın kaybolması, büyüme plağında önce uzun aksta, daha sonra transvers planda genişleme, metafizde “kadehleşme” ve fizis ile metafiz arasında “fırçalaşma” diye tabir edilen düzensizlik izlenir. Bulguların şiddeti bilateral el bilek ve diz anteroposterior grafileri kullanılarak “Rickets Severity Score” (RSS) (Raşitizm Ağırlık Skoru) ile değerlendirilmektedir. RSS tanı ve takipte kullanılabilir. Takipte ayrıca “Radiographic Global Impression of Change Scale” (RGI-C) (Genel Radyografik Değişim Ölçüsü) de kullanılabilir.

Keywords

• Grafi,raşitizm,skorlama

References

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