GEBE KADINLARDA GÖRÜLEN AKUT APANDİSİTİN TANI, TEDAVİ VE KLİNİKOPATOLOJİK ÖZELLİKLERİ VE FETAL SONUÇLAR ÜZERİNE ETKİSİ

Abstract

Amaç: Çalışmanın amacı gebe kadınlarda görülen apandisitin tanı ve tedavi stratejileri ile klinikopatolojik özellikleri ve feto-maternal sonuçlarını değerlendirmektir. Gereç ve Yöntem: Bu çalışmada apendektomi yapılan 17 gebe kadın ve yaşları eşleştirilmiş 59 gebe olmayan kadın laboratuvar bulguları, preoperatif ultrasonografi (USG), patoloji ve klinik sonuçlar açısından karşılaştırıldı. Bulgular: Toplam USG tarama sayısı, görüntülenemeyen apandis oranları ve hastanede kalış süreleri gebe kadınlarda gebe olmayan kadınlara göre daha fazla idi (sırasıyla P<0,001, P=0,035 ve P=0,014). Gebe grupta negatif apendektomi oranı gebe olmayanlara göre 1,5 kat, komplike apandisit oranı ise 7 kat daha yüksekti. USG’nin tanısal doğruluğu ise gebe olmayan grupta daha yüksek bulundu (%72,9’a karşı %64,7). Hematolojik parametreler açısından apandisit olan ve olmayan gebe hastalar arasında anlamlı bir fark bulunmadı. İkinci trimesterde bir erken doğum ve bir abortus görülürken, üçüncü trimesterde bir hastada negatif apendektomiyi takiben bir erken doğum gerçekleşti. Sonuç: Gebelik sırasında laboratuvar parametreleri ve USG ile konulan apandisit tanısı hatalı olabilmektedir. Bu yüzden, gereksiz cerrahi müdahalelerden kaçınmak için, klinisyenlerin hamilelik sırasında apandisitten şüphelendikleri durumlarda ek görüntüleme tetkikleri yapmayı düşünmelerini öneririz. Çünkü hem negatif apendektomi hem de komplike apandisit, ihmal edilemez bir fetal morbidite ve mortalite oranıyla sonuçlanabilir.

Keywords

• Akut apandisit
• gebelik
• morbidite

DIAGNOSIS, MANAGEMENT AND CLINICOPATHOLOGICAL FEATURES OF ACUTE APPENDICITIS IN PREGNANT WOMEN AND ITS IMPACT ON FETAL OUTCOMES

Abstract

Objective: To evaluate the clinicopathological features and feto- maternal outcomes of appendicitis during pregnancy. Material and Method: This study involved comparisons of laboratory findings, preoperative ultrasonography (US), pathology and clinical outcomes of 17 pregnant and 59 age-matched non-pregnant women undergoing appendectomy. Results: The total number of US scans, rates of non-visualized appendix on US, and length of hospital stay were higher in pregnant women than in non-pregnant subjects (P<0.001, P=0.035, and P=0.014; respectively). The rate of negative appendectomy was 1.5-times higher and the rate of complicated appendicitis was 7-times higher in pregnant compared with non-pregnant patients. The diagnostic accuracy of US was higher in the non-pregnant group (72.9% vs. 64.7%). In terms of the hematological parameters, no significant difference was found between the pregnant patients with and without appendicitis. There was one premature birth and one abortus in the second trimester, and one premature birth followed by a negative appendectomy in the third trimester. Conclusion: The diagnosis of acute appendicitis in pregnancy may remain inconclusive despite comprehensive evaluation with clinical examination, laboratory studies, and US. We recommend that clinicians consider additional imaging scans when they suspect appendicitis during pregnancy to avoid unnecessary surgical interventions. Both complicated appendicitis and negative appendectomy can cause a non-negligible rate of fetal morbidity and mortality.

Keywords

• Acute appendicitis
• morbidity
• pregnancy

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