GLIOBLASTOMA PRESENTED WITH DEPRESSION AND PERSONALITY CHANGES: A CASE REPORT

Abstract

Glioblastoma is the most common poor prognosis brain tumor in adults. Although neurological signs are often seen as first symptoms at clinical course of GBM, pychiatric symptoms also accompany the presentation. Mood and personality changes, anxiety and psychosis are the most common psychiatric symptoms in presentation of GBM. In this article, a 57-year-old man admitted to emergency unit with social isolation, anhedonia, loss of appetite, sleep disturbances and personality changes is reported. In this case, a 7x4 cm-sized lesion with a mass effect from the left frontoparietal region and extending to the temporal lobe was found.

Keywords

• Glioblastoma
• anhedonia
• depression
• personality changes

DEPRESYON VE KİŞİLİK DEĞİŞİKLİLERİ İLE ORTAYA ÇIKAN GLİOBLASTOMA: BİR OLGU SUNUMU

Abstract

Glioblastoma, erişkinlerde en sık görülen kötü prognozlu bir beyin tümörüdür. Her ne kadar GBM’nin klinik seyrinde ilk semptomlar nörolojik belirtiler şeklinde olsa da, psikiyatrik belirtiler de eşlik edebilir. Duygudurum ve kişilik değişiklikleri, anksiyete ve psikoz GBM’de en sık görülen psikiyatrik belirtilerdir. Bu yazıda, acil servise sosyal içe çekilme, anhedoni, iştahsızlık, uyku düzensizliği ve kişilik değişiklileri ile başvuran 57 yaşında bir erkek hasta bildirilmiştir. Bu olguda, beyin görüntüleme incelemelerinde 7x4 cm büyüklüğünde sol frontoparietal bölgeden başlayıp temporal loba uzanan ve kitle etkisi gösteren bir lezyon saptandı.

Keywords

• Glioblastoma
• anhedoni
• depresyon
• kişilik değişiklikleri

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