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RADYOAKTİF SİNOVEKTOMİNİN NONHEMOFİLİK SİNOVİTLERDE HASTA MEMNUNİYETİ ÜZERİNE ETKİSİ

Year 2017, Volume: 80 Issue: 1, 13 - 19, 31.03.2017
https://doi.org/10.18017/iuitfd.309198

Abstract

Amaç: Radyoaktif sinovektomi (RAS) uygulanmış hemofili dışı sinovit
hastalarında memnuniyet düzeyinin ve bunu etkileyen etmenlerin
değerlendirilmesi

Gereç ve Yöntem: 2002-2013 arasında RAS uygulanmış hemofili dışı
sinovit hastalarından ulaşılabilen ve telefon anketine katılmayı kabul eden 21
hasta çalışmaya dahil edildi. Hastaların 16’sında romatizmal hastalık vardı; 21
hastanın 25’i diz, ikisi dirsek ve üçü ayak bileği eklemi olmak üzere 30
eklemine 41 enjeksiyon yapılmıştı. Yirmi altı ekleme cerrahi sinovektomi
yapılmıştı. Telefon anketinde temel yakınma, her enjeksiyon için hastanın
yararlanım algısı, şişlikte gerileme ya da tekrarlama ve memnuniyetleri
sorgulandı. Ağrı ve işlevsellik için telefonla diz değerlendirme formu
dolduruldu.

Bulgular: Temel yakınma eklemlerin 23 tanesinde (%76,7)
şişlikti. Birinci enjeksiyon 14 eklemde (%46,7) yararlı, dört eklemde (%13,3)
kısmen yararlı, 12 eklemdeyse (%40) faydasız olarak değerlendirildi. On dokuz
eklemde (%63,3) şişlik tamamen, üç eklemde (%10) kısmen geriledi; 10 eklemdeyse
(%33,3) tekrarladı. Hastalar, eklemlerin 20’sinin (%66,7) klinik sonucundan
memnundu. Dizin ağrı ve işlev skorlarının medyan değeri 80’di; iki skor
bakımından memnun olan ve olmayanlar arasında anlamlı fark saptanmadı. Spesifik
bir romatizmal hastalığı olmayanlarda ağrı skoru anlamlı olarak daha iyi
bulundu (p=0.031); bu hastalar uygulanan girişimden daha memnundu (p=0.045).
Şişliğin devam etmesi, tekrarlaması ve yürüme güçlüğü olması hasta
memnuniyetini olumsuz etkileyen etmenler olarak değerlendirildi.

Sonuç: Romatizmal hastalığı olmayanlarda memnuniyet oranının daha yüksek
olması, sistemik hastalığı olanlarda uzun süreli tatminkar sonuç elde
edebilmenin zorluğuyla ilişkili görünmektedir. Memnuniyet üzerinde en etkili
faktör şişliktir. Yüksek nüks riski varlığında ve çok sayıda cerrahi girişimden
kaçınmak için RAS uygun bir seçenektir.









Anahtar
Sözcükler:
Radyoaktif
sinovektomi; sinovit; hasta memnuniyeti.

References

  • 1. Karavida N, Notopoulos A. Radiation Synovectomy: an effective alternative treatment for inflamed small joints. Hippokratia 2010; 14(1): 22–7.
  • 2. Schneider P, Farahati J, Reiners C. Radiosynovectomy in rheumatology, orthopedics, and hemophilia. J Nucl Med 2005;46 Suppl 1:48S-54S.
  • 3. Stucki G, Bozzone P, Treuer E, Wassmer P, Felder M. Efficacy and safety of radiation synovectomy with Yttrium-90: a retrospective long-term analysis of 164 applications in 82 patients. Br J Rheumatol 1993;32(5):383-6.
  • 4. Knut L. Radiosynovectomy in the therapeutic management of arthritis. World J Nucl Med 2015;14(1):10-5. 5. Norouzbeigi N, Zakavi SR, Ayati NK, Farahati J, Sadeghi R, Mirfeizi Z. Efficacy of radiosynovectomy in the treatment of chronic knee synovitis: Systematic review and meta-analysis. Iran J Nucl Med 2015;23(2):59-64.
  • 6. Das BK, Pradhan PK, Shukla AK, Misra R. Role of radiosynovectomy in rheumatoid arthritis.J Indian Rheumatol Assoc 2004;12:98 - 103.
  • 7. Heuft-Dorenbosch LL, de Vet HC, van der Linden S. Yttrium radiosynoviorthesis in the treatment of knee arthritis in rheumatoid arthritis: a systematic review. Ann Rheum Dis 2000;59(8):583-6.
  • 8. Ćwikła JB, Żbikowski P, Kwiatkowska B, Buscombe JR, Sudoł-Szopińska I. Radiosynovectomy in rheumatic diseases. J Ultrason 2014;14(58):241-51.
  • 9. Fischer M, Mödder G. Radionuclide therapy of inflammatory joint diseases. Nucl Med Commun 2002;23(9):829-31.
  • 10. Momohara S, Ikeda M, Uchida K, Kawamura K, Mizumura T, Tomatsu T. Follow-up results of arthroscopic synovectomy for the rheumatoid knee. Mod Rheumatol 2001;11(3):205-9.
  • 11. Zwolak R, Majdan M, Skorski M, Chrapko B. Efficacy of radiosynoviorthesis and its impact on chosen inflammatory markers. Rheumatol Int. 2012;32:2339-2344.
  • 12. Zalewska J, Węgierska M, Barczyńska T, Waszczak M, Żuchowski P, Jeka S. Efficacy of radiation synovectomy (radiosynovectomy or radiosynoviorthesis) with yttrium-90 in exudative inflammation of synovial membrane of knee joints in patients with rheumatic diseases - preliminary report. Reumatologia. 2016;54(1):3-9.
  • 13. Liepe K. Efficacy of radiosynovectomy in rheumatoid arthritis. Rheumatol Int 2012;32:3219-3224.
  • 14. Jahangier ZN, Moolenburgh JD, Jacobs JW, Serdijn H, Bijlsma JW. The effect of radiation synovectomy in patients with persistent arthritis: a prospective study. Clin Exp Rheumatol 2001;19(4):417-24.
  • 15. Kresnik E, Mikosch P, Gallowitsch HJ, Jesenko R, Just H, Kogler D, Gasser J, Heinisch M, Unterweger O, Kumnig G, Gomez I, Lind P. Clinical outcome of radiosynoviorthesis: a meta-analysis including 2190 treated joints. Nucl Med Commun 2002;23(7):683-8.
  • 16. Wong Y, Cherk MH, Powell A, Cicuttini F, Bailey M, Kalff V. Efficacy of yttrium-90 synovectomy across a spectrum of arthropathies in an era of improved disease modifying drugs and treatment protocols. Int J Rheum Dis 2014;17(1):78-83.
  • 17. Worland RL, Johnson GV, Alemparte J, Jessup DE, Keenan J, Norambuena N. Ten to fourteen year survival and functional analysis of the AGC total knee replacement system. Knee 2002;9(2):133-7.
  • 18. Klug S, Wittmann G, Weseloh G. Arthroscopic synovectomy of the knee joint in early cases of rheumatoid arthritis: follow-up results of a multicenter study. Arthroscopy 2000;16(3):262-7.
  • 19. Goetz M, Klug S, Gelse K, Swoboda B, Carl HD. Combined arthroscopic and radiation synovectomy of the knee joint in rheumatoid arthritis: 14-year follow-up. Arthroscopy 2011;27(1):52-9.
  • 20. Akmeşe R, Yıldız Kİ, Işık Ç, Tecimel O, Bilgetekin YG, Fırat A, Özakıncı H, Bozkurt M. Combined arthroscopic synovectomy and radiosynoviorthesis in the treatment of chronic non‐specific synovitis of the knee. Arch Orthop Traum Surg 2013;133:1567–73.

PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS

Year 2017, Volume: 80 Issue: 1, 13 - 19, 31.03.2017
https://doi.org/10.18017/iuitfd.309198

Abstract

Objective: To evaluate satisfaction rates of nonhemophilic
synovitis patients who underwent radioactive synovectomy (RAS), to outline the
factors influencing patient satisfaction.

Material and Methods: RAS was performed to 31 nonhemophilic patients
between 2002 and 2013; 21 patients were reached and agreed to make an interview
on the phone. Twenty five of 30 joints were knee, two were elbow, and three
were ankle; 41 injections were performed. Twenty six joints had surgical synovectomy.
Primary complaints before and after RAS, patients’ perception of benefits,
subsidence and recurrence of swelling and patient satisfaction were questioned.
An over the phone knee evaluation form was filled which scored pain and
functionality.

Results: Swelling was the primary complaint in 23 joints
(76.7%). First RAS injection was beneficial for 14 joints (46.7%), partially
beneficial for four (13.3%), and not beneficial for 12 (40%). Swelling subsided
completely in 19 joints (63.3%), partially in three (10%); recurred in 10
joints (33.3%). Satisfaction rate was 66.7%. Median values for pain and
function scores were both 80. The ones without a specific rheumatic disease had
significantly better pain scores (p=0.031), and were more satisfied with the procedure
(p=0.045). Patient satisfaction was influenced by persistence and recurrence of
swelling and restriction of walking.

Conclusion: Satisfaction rate of patients without a rheumatic
disease was significantly higher. In case of systemic diseases, obtaining
durable successful outcomes is more challenging. Swelling was the most
influential factor on satisfaction. In cases of high recurrence risk, RAS is an
alternative to avoid multiple operations.

Key words: Radioactive synovectomy; synovitis; patient satisfaction.

References

  • 1. Karavida N, Notopoulos A. Radiation Synovectomy: an effective alternative treatment for inflamed small joints. Hippokratia 2010; 14(1): 22–7.
  • 2. Schneider P, Farahati J, Reiners C. Radiosynovectomy in rheumatology, orthopedics, and hemophilia. J Nucl Med 2005;46 Suppl 1:48S-54S.
  • 3. Stucki G, Bozzone P, Treuer E, Wassmer P, Felder M. Efficacy and safety of radiation synovectomy with Yttrium-90: a retrospective long-term analysis of 164 applications in 82 patients. Br J Rheumatol 1993;32(5):383-6.
  • 4. Knut L. Radiosynovectomy in the therapeutic management of arthritis. World J Nucl Med 2015;14(1):10-5. 5. Norouzbeigi N, Zakavi SR, Ayati NK, Farahati J, Sadeghi R, Mirfeizi Z. Efficacy of radiosynovectomy in the treatment of chronic knee synovitis: Systematic review and meta-analysis. Iran J Nucl Med 2015;23(2):59-64.
  • 6. Das BK, Pradhan PK, Shukla AK, Misra R. Role of radiosynovectomy in rheumatoid arthritis.J Indian Rheumatol Assoc 2004;12:98 - 103.
  • 7. Heuft-Dorenbosch LL, de Vet HC, van der Linden S. Yttrium radiosynoviorthesis in the treatment of knee arthritis in rheumatoid arthritis: a systematic review. Ann Rheum Dis 2000;59(8):583-6.
  • 8. Ćwikła JB, Żbikowski P, Kwiatkowska B, Buscombe JR, Sudoł-Szopińska I. Radiosynovectomy in rheumatic diseases. J Ultrason 2014;14(58):241-51.
  • 9. Fischer M, Mödder G. Radionuclide therapy of inflammatory joint diseases. Nucl Med Commun 2002;23(9):829-31.
  • 10. Momohara S, Ikeda M, Uchida K, Kawamura K, Mizumura T, Tomatsu T. Follow-up results of arthroscopic synovectomy for the rheumatoid knee. Mod Rheumatol 2001;11(3):205-9.
  • 11. Zwolak R, Majdan M, Skorski M, Chrapko B. Efficacy of radiosynoviorthesis and its impact on chosen inflammatory markers. Rheumatol Int. 2012;32:2339-2344.
  • 12. Zalewska J, Węgierska M, Barczyńska T, Waszczak M, Żuchowski P, Jeka S. Efficacy of radiation synovectomy (radiosynovectomy or radiosynoviorthesis) with yttrium-90 in exudative inflammation of synovial membrane of knee joints in patients with rheumatic diseases - preliminary report. Reumatologia. 2016;54(1):3-9.
  • 13. Liepe K. Efficacy of radiosynovectomy in rheumatoid arthritis. Rheumatol Int 2012;32:3219-3224.
  • 14. Jahangier ZN, Moolenburgh JD, Jacobs JW, Serdijn H, Bijlsma JW. The effect of radiation synovectomy in patients with persistent arthritis: a prospective study. Clin Exp Rheumatol 2001;19(4):417-24.
  • 15. Kresnik E, Mikosch P, Gallowitsch HJ, Jesenko R, Just H, Kogler D, Gasser J, Heinisch M, Unterweger O, Kumnig G, Gomez I, Lind P. Clinical outcome of radiosynoviorthesis: a meta-analysis including 2190 treated joints. Nucl Med Commun 2002;23(7):683-8.
  • 16. Wong Y, Cherk MH, Powell A, Cicuttini F, Bailey M, Kalff V. Efficacy of yttrium-90 synovectomy across a spectrum of arthropathies in an era of improved disease modifying drugs and treatment protocols. Int J Rheum Dis 2014;17(1):78-83.
  • 17. Worland RL, Johnson GV, Alemparte J, Jessup DE, Keenan J, Norambuena N. Ten to fourteen year survival and functional analysis of the AGC total knee replacement system. Knee 2002;9(2):133-7.
  • 18. Klug S, Wittmann G, Weseloh G. Arthroscopic synovectomy of the knee joint in early cases of rheumatoid arthritis: follow-up results of a multicenter study. Arthroscopy 2000;16(3):262-7.
  • 19. Goetz M, Klug S, Gelse K, Swoboda B, Carl HD. Combined arthroscopic and radiation synovectomy of the knee joint in rheumatoid arthritis: 14-year follow-up. Arthroscopy 2011;27(1):52-9.
  • 20. Akmeşe R, Yıldız Kİ, Işık Ç, Tecimel O, Bilgetekin YG, Fırat A, Özakıncı H, Bozkurt M. Combined arthroscopic synovectomy and radiosynoviorthesis in the treatment of chronic non‐specific synovitis of the knee. Arch Orthop Traum Surg 2013;133:1567–73.
There are 19 citations in total.

Details

Subjects Health Care Administration
Journal Section Clinical Research
Authors

Elcil Kaya Biçer

Semih Aydoğdu

Hakkı Sur This is me

Publication Date March 31, 2017
Submission Date April 26, 2017
Published in Issue Year 2017 Volume: 80 Issue: 1

Cite

APA Kaya Biçer, E., Aydoğdu, S., & Sur, H. (2017). PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS. Journal of Istanbul Faculty of Medicine, 80(1), 13-19. https://doi.org/10.18017/iuitfd.309198
AMA Kaya Biçer E, Aydoğdu S, Sur H. PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS. İst Tıp Fak Derg. March 2017;80(1):13-19. doi:10.18017/iuitfd.309198
Chicago Kaya Biçer, Elcil, Semih Aydoğdu, and Hakkı Sur. “PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS”. Journal of Istanbul Faculty of Medicine 80, no. 1 (March 2017): 13-19. https://doi.org/10.18017/iuitfd.309198.
EndNote Kaya Biçer E, Aydoğdu S, Sur H (March 1, 2017) PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS. Journal of Istanbul Faculty of Medicine 80 1 13–19.
IEEE E. Kaya Biçer, S. Aydoğdu, and H. Sur, “PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS”, İst Tıp Fak Derg, vol. 80, no. 1, pp. 13–19, 2017, doi: 10.18017/iuitfd.309198.
ISNAD Kaya Biçer, Elcil et al. “PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS”. Journal of Istanbul Faculty of Medicine 80/1 (March 2017), 13-19. https://doi.org/10.18017/iuitfd.309198.
JAMA Kaya Biçer E, Aydoğdu S, Sur H. PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS. İst Tıp Fak Derg. 2017;80:13–19.
MLA Kaya Biçer, Elcil et al. “PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS”. Journal of Istanbul Faculty of Medicine, vol. 80, no. 1, 2017, pp. 13-19, doi:10.18017/iuitfd.309198.
Vancouver Kaya Biçer E, Aydoğdu S, Sur H. PATIENT SATISFACTION FOLLOWING RADIOACTIVE SYNOVECTOMY IN NONHEMOPHILIC SYNOVITIS. İst Tıp Fak Derg. 2017;80(1):13-9.

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Addressi: İ.Ü. İstanbul Tıp Fakültesi Dekanlığı, Turgut Özal Cad. 34093 Çapa, Fatih, İstanbul, TÜRKİYE

Email: itfdergisi@istanbul.edu.tr

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