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İLKÖĞRETİM ÇAĞINDAKİ ÇOCUKLARDA İDRAR DİPSTİCK TARAMA TESTİ SONUÇLARI

Year 2020, Volume: 83 Issue: 3, 254 - 258, 29.06.2020

Abstract

Amaç: Renal hastalıklar herhangi bir semptoma neden olmadan hematüri ve proteinüri ile ortaya çıkabilirler. Çalışmamızın amacı sağlıklı, okul çağındaki çocuklarda idrar analizi anormalliklerinin idrar dipstick testi ile değerlendirilmesidir. Gereç ve Yöntem: Yaşları 9-10 aralığında olan 1052 (541, erkek, 511 kız) çocuğun idrar dipstick test sonuçları değerlendirildi. İlk idrar analizinde anormallik tespit edilen çocuklarda kalıcı hematüri ve proteinürinin değerlendirilmesi için ikinci bir idrar dipsitick testi yapıldı. Bulgular: Anormal idrar dipstick test sonucu 137 (%13) hastada tespit edildi. On altı (%1,5) çocukta izole hematüri, 22 (%2,1) çocukta izole proteinüri ve bir (%0,1) çocukta kombine hematuria ve proteinuri tespit edildi. İkinci idrar dipsitick testinde hematürinin yanlızca 8 çocukta (%0,8) ve proteinurinin 2 (%0,2) çocukta persiste ettiği görüldü. Ayrıca ilk idrar analizinde 96 (%9,1) çocukta lökosit esteraz pozitifliği, 18 (%1,7) çocukta nitrit pozitifliği, 10 (%0,95) çocukta hem lökosit esteraz hem de nitrit pozitifliği tespit edildi. Sonuç: Çalışmamızın sonuçlarında ikinci bir idrar analizi yapıldığında hematüri ve proteinüri sıklığının düştüğü görülmüştür. Bu nedenle izole hematüri ya da proteinüri saptanan asemptomatik hastalar ikinci bir idrar analizi ile yeniden değerlendirilmelidir. Çalışmamızın sonuçları okul çağı çocuklarında dipstick tarama testi ile hematüri ve proteinüri tespit edilebileceğini ve bu durum böbrek hastalıklarının asemptomatik döneminin bulgusu olabileceğini göstermektedir.

References

  • 1. Yamagata K, Iseki K, Nitta K, Imai H, Iino Y, Matsuo S. Chronic kidney disease perspectives in Japan and the importance of urinalysis screening. Clin Exp Nephrol 2008;12:1-8.
  • 2. Lin CY, Hsieh CC, Chen WP, Yang LY, Wang HH. The underlying diseases and follow-up in Taiwanese children screened by urinalysis. Pediatr Nephrol 2001;16(3):232-7.
  • 3. Schumann GB, Greenberg NF. Usefulness of macroscopic urinalysis as a screening procedure. Am Soc Clin Pathol 1979;71:452-6.
  • 4. Shaw ST, Poon SY, Wong ET. Routine urinalysis. Is the dipstick enough? JAMA 1985;253:1596-600.
  • 5. Koyama A, Igarashi M, Kobayashi M. Naturals history and risk factors for immunoglobulin A nephropathy. Am J Kid Dis. 1997;29:526-32.
  • 6. Kemper KJ, Avner ED. The case against screening urinalyses for asymptomatic bacteriuria in children. Am J Dis Child 1992;146:34346.
  • 7. Stevens PE, Levin A. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med 2013;158(11):825-30.
  • 8. Recommendations for Preventive Pediatric Health Care. Pediatrics, 2007;120(6):1376.
  • 9. Lin CY, Sheng CC, Chen CH, Lin CC, Chou P. The prevalence of heavy proteinuria and progression risk factors in children undergoing urinary screening. Pediatr Nephrol 2002;14:9539.
  • 10. Murakami M, Yamamoto H, Ueda Y, Murakami K, Yamauchi K. Urinary screening of elementary and junior high-school children over a 13-year period in Tokyo. Pediatr Nephrol 1991;5:50-3.
  • 11. Cho BS, Kim SD, Choi YM, Kang HH. School urinalysis screening in Korea: prevalence of chronic renal disease. Pediatr Nephrol 2001;16:1126-8.
  • 12. Halbesma N, Kuiken DS, Brantsma AH, Bakker SJ, Wetzels JF. De estimated GFR to identify individuals at risk for accelerated GFR loss in population screening. J Am Soc Nephrol 2006;17:2582-90.
  • 13. Yayli G, Yaman H, Demirdal T. Asymptomatic bacteriuria rates in schoolchildren: results from a rural city in Turkey. J Trop Pediatr 2003;49:228-30.
  • 14. Yenisay C, Sonmez F. Aydın’da okul çağı çocuklarında asemptomatik hematüri, proteinüri, pyüri taraması. Adnan Menderes Ünv Araştırmaları, 1999.
  • 15. Mir S, Keskinoglu A, Ozkayın N, Ozdemir O. İlkokul 1. Sınıf çocuklarında asemptomatik idrar yolu enfeksiyonu ve hipertansiyon prevalansı. Ege Tıp Dergisi 2005;44(1):29-33.
  • 16. Ünalacak M, Armutcu F, Demirel F, Gürel A, Demircan N, Aktunç E. Okul çağı çocuklarda mikroskopik idrar incelemesi ile asemptomatik bakteriüri sıklığı. Tıp Araştırmaları Dergisi 2005;3:30-2.
  • 17. Nebigil I, Tumer N. Asymptomatic urinary tract infection in childhood. Eur J Pediatr 1992;151(4):308-9.
  • 18. Murakami M. Screening for proteinuria and hematuria in schoolchildren methods and results. Acta Paediatr Jpn 1990;32(6):682-9.
  • 19. Lin CY, Sheng CC, Lin CC, Chen CH, Chou P. Mass urinary screening and follow- up for schoolchildren in Taiwan province. Acta Paediatr Taiwan 2001;42(3):134-140.
  • 20. Ruggenenti P, Perna A, Mosconi L, Pisoni R, Remuzzi G. Urinary protein excretion rate is the best independent predictor of ESRF in non- diabetic proteinuric chronic nephropathies. “Gruppo Italiano di Studi Epidemiological Nefrologia” (GISEN). Kidney Int 1998;53:1209-16.
  • 21. Suleymanlar G, Utas C, Arınsoy T, et al. A population based survey of chronic renal disease in Turkey - The CREDIT study. Nephrol Dial Transplant 2011;26:1862-71.
  • 22. Ambo K, Tsuchiya M, Murakami M, et al. Incidence of abnormalities in urinalysis in Japanese children aged six to ten years (in Japanese). J Jpn Pediatr Soc 1999;103:543-8.
  • 23. Murakami M, Hayakawa M, Yanagihara T, Hukunaga Y. Proteinuria screening for children. Kidney Int Suppl 2005;(94):23-7.
  • 24. Ates K. Türkiye’de Nefroloji, Diyaliz ve Transplantasyon – Registry 2017. Available from URL: http://www.nefroloji.org. tr/folders/file/18104_REGISTRY2017_kontrol_v1.pdf
  • 25. Lin CY, Hsieh CC, Chen WP, Yang LY, Wang HH. The underlying diseases and follow-up in Taiwanese children screened by urinalysis. Pediatr Nephrol 2001;16:232-7.
  • 26. Yap HK, Quek CM, Shen Q, Chia KS. Role of Urinary Screening Programmes in Children in the Prevention of Chronic Kidney Disease. Ann Acad Med Singapore 2005;34:3-7.
  • 27. Zainal D, Baba A, Mustaffa BE. Screening proteinuria and haematuria in Malaysian Children. SoutheastAsian J Trop Med Public Health 1995;26:785-8.
  • 28. Cho BS, Hahn WH, Cheong HI, Lim I, Ko CW, Kim SY, Suh JS. A nation wide study of mass urine screening tests on Korean school children and implications for chronic kidney disease management. Clin Exp Nephrol 2013;17(2):205-10.
  • 29. Vernon S, Lundblad B, Hellstrom AL. Children’s experiences of school toilets present a risk to their physicaland psychological health. Child Care Health Dev 2003;29:47-53.

RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN

Year 2020, Volume: 83 Issue: 3, 254 - 258, 29.06.2020

Abstract

Objective: Renal diseases may present with proteinuria, hematuria and pyuria without any symptoms. The aim of the study is to determine of urinalysis abnormalities by urine dipstick screening program in healthy school-aged children. Material and Method: We evaluated results of urine dipstick tests of 1052 children (541 male, 511 female) between the ages of 9 and 10. A second urine dipstick test was performed on those students who had hematuria and/or proteinuria in the first test. Results: Abnormality in urine dipstick test was detected in a total of 137 (13%) children. Sixteen cases had isolated hematuria (1.5%), 22 cases isolated proteinuria (2.1%) and one case (0.1%) combined hematuria-proteinuria. In the second evaluation with the dipstick test, we determined that hematuria persisted only in 8 (0.8%) and proteinuria in 2 cases (0.2%). Additionally, 96 cases (9.1%) were positive for leucocyte-esterase, and 18 cases (1.7%) were nitrite positive in the first screening. Conclusion: Our findings revealed that prevalence of hematuria and proteinuria was reduced in the second urine dipstick screening. Therefore, asymptomatic patients with isolated proteinuria or hematuria should be re-evaluated with a urine dipstick. Our study suggests that with the help of screening tests in schoolaged children; hematuria, and proteinuria can be determined and this might be an indication for the asymptomatic period of a kidney disease.

References

  • 1. Yamagata K, Iseki K, Nitta K, Imai H, Iino Y, Matsuo S. Chronic kidney disease perspectives in Japan and the importance of urinalysis screening. Clin Exp Nephrol 2008;12:1-8.
  • 2. Lin CY, Hsieh CC, Chen WP, Yang LY, Wang HH. The underlying diseases and follow-up in Taiwanese children screened by urinalysis. Pediatr Nephrol 2001;16(3):232-7.
  • 3. Schumann GB, Greenberg NF. Usefulness of macroscopic urinalysis as a screening procedure. Am Soc Clin Pathol 1979;71:452-6.
  • 4. Shaw ST, Poon SY, Wong ET. Routine urinalysis. Is the dipstick enough? JAMA 1985;253:1596-600.
  • 5. Koyama A, Igarashi M, Kobayashi M. Naturals history and risk factors for immunoglobulin A nephropathy. Am J Kid Dis. 1997;29:526-32.
  • 6. Kemper KJ, Avner ED. The case against screening urinalyses for asymptomatic bacteriuria in children. Am J Dis Child 1992;146:34346.
  • 7. Stevens PE, Levin A. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med 2013;158(11):825-30.
  • 8. Recommendations for Preventive Pediatric Health Care. Pediatrics, 2007;120(6):1376.
  • 9. Lin CY, Sheng CC, Chen CH, Lin CC, Chou P. The prevalence of heavy proteinuria and progression risk factors in children undergoing urinary screening. Pediatr Nephrol 2002;14:9539.
  • 10. Murakami M, Yamamoto H, Ueda Y, Murakami K, Yamauchi K. Urinary screening of elementary and junior high-school children over a 13-year period in Tokyo. Pediatr Nephrol 1991;5:50-3.
  • 11. Cho BS, Kim SD, Choi YM, Kang HH. School urinalysis screening in Korea: prevalence of chronic renal disease. Pediatr Nephrol 2001;16:1126-8.
  • 12. Halbesma N, Kuiken DS, Brantsma AH, Bakker SJ, Wetzels JF. De estimated GFR to identify individuals at risk for accelerated GFR loss in population screening. J Am Soc Nephrol 2006;17:2582-90.
  • 13. Yayli G, Yaman H, Demirdal T. Asymptomatic bacteriuria rates in schoolchildren: results from a rural city in Turkey. J Trop Pediatr 2003;49:228-30.
  • 14. Yenisay C, Sonmez F. Aydın’da okul çağı çocuklarında asemptomatik hematüri, proteinüri, pyüri taraması. Adnan Menderes Ünv Araştırmaları, 1999.
  • 15. Mir S, Keskinoglu A, Ozkayın N, Ozdemir O. İlkokul 1. Sınıf çocuklarında asemptomatik idrar yolu enfeksiyonu ve hipertansiyon prevalansı. Ege Tıp Dergisi 2005;44(1):29-33.
  • 16. Ünalacak M, Armutcu F, Demirel F, Gürel A, Demircan N, Aktunç E. Okul çağı çocuklarda mikroskopik idrar incelemesi ile asemptomatik bakteriüri sıklığı. Tıp Araştırmaları Dergisi 2005;3:30-2.
  • 17. Nebigil I, Tumer N. Asymptomatic urinary tract infection in childhood. Eur J Pediatr 1992;151(4):308-9.
  • 18. Murakami M. Screening for proteinuria and hematuria in schoolchildren methods and results. Acta Paediatr Jpn 1990;32(6):682-9.
  • 19. Lin CY, Sheng CC, Lin CC, Chen CH, Chou P. Mass urinary screening and follow- up for schoolchildren in Taiwan province. Acta Paediatr Taiwan 2001;42(3):134-140.
  • 20. Ruggenenti P, Perna A, Mosconi L, Pisoni R, Remuzzi G. Urinary protein excretion rate is the best independent predictor of ESRF in non- diabetic proteinuric chronic nephropathies. “Gruppo Italiano di Studi Epidemiological Nefrologia” (GISEN). Kidney Int 1998;53:1209-16.
  • 21. Suleymanlar G, Utas C, Arınsoy T, et al. A population based survey of chronic renal disease in Turkey - The CREDIT study. Nephrol Dial Transplant 2011;26:1862-71.
  • 22. Ambo K, Tsuchiya M, Murakami M, et al. Incidence of abnormalities in urinalysis in Japanese children aged six to ten years (in Japanese). J Jpn Pediatr Soc 1999;103:543-8.
  • 23. Murakami M, Hayakawa M, Yanagihara T, Hukunaga Y. Proteinuria screening for children. Kidney Int Suppl 2005;(94):23-7.
  • 24. Ates K. Türkiye’de Nefroloji, Diyaliz ve Transplantasyon – Registry 2017. Available from URL: http://www.nefroloji.org. tr/folders/file/18104_REGISTRY2017_kontrol_v1.pdf
  • 25. Lin CY, Hsieh CC, Chen WP, Yang LY, Wang HH. The underlying diseases and follow-up in Taiwanese children screened by urinalysis. Pediatr Nephrol 2001;16:232-7.
  • 26. Yap HK, Quek CM, Shen Q, Chia KS. Role of Urinary Screening Programmes in Children in the Prevention of Chronic Kidney Disease. Ann Acad Med Singapore 2005;34:3-7.
  • 27. Zainal D, Baba A, Mustaffa BE. Screening proteinuria and haematuria in Malaysian Children. SoutheastAsian J Trop Med Public Health 1995;26:785-8.
  • 28. Cho BS, Hahn WH, Cheong HI, Lim I, Ko CW, Kim SY, Suh JS. A nation wide study of mass urine screening tests on Korean school children and implications for chronic kidney disease management. Clin Exp Nephrol 2013;17(2):205-10.
  • 29. Vernon S, Lundblad B, Hellstrom AL. Children’s experiences of school toilets present a risk to their physicaland psychological health. Child Care Health Dev 2003;29:47-53.
There are 29 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section RESEARCH
Authors

Günay Muradova This is me 0000-0001-8211-1182

Zeynep Yürük Yıldırım This is me 0000-0003-2891-2231

Özde Nisa Türkkan This is me 0000-0003-2928-9031

Ahmet Nayır This is me 0000-0002-3357-9237

Publication Date June 29, 2020
Submission Date May 13, 2019
Published in Issue Year 2020 Volume: 83 Issue: 3

Cite

APA Muradova, G., Yürük Yıldırım, Z., Türkkan, Ö. N., Nayır, A. (2020). RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN. Journal of Istanbul Faculty of Medicine, 83(3), 254-258.
AMA Muradova G, Yürük Yıldırım Z, Türkkan ÖN, Nayır A. RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN. İst Tıp Fak Derg. June 2020;83(3):254-258.
Chicago Muradova, Günay, Zeynep Yürük Yıldırım, Özde Nisa Türkkan, and Ahmet Nayır. “RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN”. Journal of Istanbul Faculty of Medicine 83, no. 3 (June 2020): 254-58.
EndNote Muradova G, Yürük Yıldırım Z, Türkkan ÖN, Nayır A (June 1, 2020) RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN. Journal of Istanbul Faculty of Medicine 83 3 254–258.
IEEE G. Muradova, Z. Yürük Yıldırım, Ö. N. Türkkan, and A. Nayır, “RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN”, İst Tıp Fak Derg, vol. 83, no. 3, pp. 254–258, 2020.
ISNAD Muradova, Günay et al. “RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN”. Journal of Istanbul Faculty of Medicine 83/3 (June 2020), 254-258.
JAMA Muradova G, Yürük Yıldırım Z, Türkkan ÖN, Nayır A. RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN. İst Tıp Fak Derg. 2020;83:254–258.
MLA Muradova, Günay et al. “RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN”. Journal of Istanbul Faculty of Medicine, vol. 83, no. 3, 2020, pp. 254-8.
Vancouver Muradova G, Yürük Yıldırım Z, Türkkan ÖN, Nayır A. RESULTS OF URINE DIPSTICK SCREENING TEST IN ELEMENTARY SCHOOL CHILDREN. İst Tıp Fak Derg. 2020;83(3):254-8.

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