COVID-19 PNÖMONİSİNİ TAKLİT EDEN SİSTEMİK LUPUS ERİTHEMATOSUS VAKASI

Year 2021, Volume: 84 Issue: 4, 595 - 598, 01.10.2021

Ece Şahinoğlu Serap Argun Barış Sevtap Doğan Aynur Karadenizli İlknur Başyiğit

https://doi.org/10.26650/IUITFD.2021.912861

Abstract

Koronavirüs hastalığı (COVID-19), dünya genelinde yüksek mortalite oranına sahip sağlık acil durumudur. Radyolojik bulguların COVID-19 ile uyumlu olmasının yanında, reverse transkripsiyon- polimeraz zincir reaksiyon (RT-PCR) testinin pozitifliği tanı için gereklidir. Bu çalışmada, 63 yaşında akciğer kanseri ve sistemik lupus eritematozus (SLE) öyküsü olan, öksürük ve nefes darlığı ile başvuran bir kadın hasta sunuldu. Toraks tomografisinde; COVID-19 pnömonisi ile uyumlu olan her iki akciğer alanlarında da yaygın buzlu cam dansiteleri saptandı. İki kez bakılan RT-PCR testi negatif olarak raporlandı. Hidroksiklorokin, azitromisin ve piperasilin-tazobaktam tedavisi sonrası anlamlı bir radyolojik düzelme görülemedi. SLE’nin akciğer tutulumu olabileceği düşünülerek metilprednizolon başlanan hastanın semptomlarında ve radyolojik bulgularında iyileşme izlendi. Altta yatan hastalıklar COVID-19 enfeksiyonunu taklit edebilir veya hastalığın belirti ve bulguları COVID-19 ile birlikte görülebilir.

Keywords

COVID-19, pnömoni, sistemik lupus eritematozus, ayırıcı tanı

A CASE WITH SYSTEMIC LUPUS ERITHEMATOSUS MIMICKING COVID-19 PNEUMONIA

Abstract

Coronavirus-19 disease (COVID-19) is a worldwide health emergency which has a high mortality ratio. Diagnosis requires a positive reverse transcription-polymerase chain reaction (RT-PCR) test however there are radiological findings strongly suggest the diagnosis of COVID-19. Here we reported a 63-year-old woman presented with cough and dyspnea and medical history of lung cancer and systemic lupus erythematosus (SLE). Chest computed tomography demonstrated widespread ground glass opacities in both lung fields that have been reported to be compatible with COVID-19 pneumonia. RT-PCR test was negative for twice and radiological regression after hydroxychloroquine, azithromycin and piperacillin-tazobactam was not significant. Considering lung involvement of SLE methylprednisolone was initiated, symptoms and radiological findings improved. The underlying diseases may mimic the COVID-19 infection or the signs and symptoms of the disease may be seen together with COVID-19.

Keywords

COVID-19, pneumonia, systemic lupus erythematosus, differential diagnosis

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