DİYABETİK KETOASİDOZLU OLGULARDA OPTİK SİNİR KILIF ÇAPI ÖLÇÜMÜ İLE BEYİN ÖDEMİ ÖNGÖRÜLEBİLİR Mİ?: BİR ÖNCÜL ÇALIŞMA

Year 2022, Volume: 85 Issue: 2, 270 - 274, 24.03.2022

Özlem Kendir Hayri Yılmaz Nilgun Erkek Sinem Sarı Gökay Dinçer Yıldızdaş Bilgin Yüksel

https://doi.org/10.26650/IUITFD.972539

Abstract

Amaç: Diyabetik ketoasidozda (DKA) beyin ödeminin klinik belirti ve semptomları her zaman açık olmayabilir. İntrakraniyal basınç arttığında, optik sinir kılıfı çapı (OSKÇ) aynı anda artar ve ultrasonografi ile görüntülenebilir. Bu çalışmada, DKA’da beyin ödemi (BÖ) varlığında OSKÇ değerlerinin belirleyici özelliklerinin tartışılması amaçlandı. Gereç ve Yöntem: Çalışmaya hafif, orta ve şiddetli DKA tanılı hastalar dahil edildi. Tedavinin ilk iki saatinde hastanın gözleri kapalı, sırtüstü nötral pozisyonda yatarken transorbital ultrasonografi uygulandı. Globun 3 mm derinliğinde hipoekoik çift kenarlı bir çizgi olarak görünen optik sinir kılıf çapları ölçüldü. Poliklinik kontrollerinde de aynı ölçümler tekrarlandı. Hastaların OSKÇ değerleri ile metabolik ve nörolojik durumları karşılaştırıldı. Bulgular: Yaş ortalaması 8,8±3 (SS) yıl olan sekiz hasta çalışmaya dahil edildi. Bunlardan yedisinde orta-şiddetli DKA vardı. Bilgisayarlı beyin tomografisinde (BT) baş ağrısı olan iki hastanın hafif BÖ olduğu görüldü. Orta-şiddetli DKA’lı hastalarda OSKÇ 5,7±0,93 mm (ortalama±SD (Standard Sapma)), hafif DKA’lı tek hastada ise 4 mm idi. BT’de BÖ’lü 2 hastanın OSKÇ’si 6,8 mm ve 5,9 mm idi. Şiddetli DKA’lı beş hastanın tedaviden bir hafta sonraki poliklinik kontrolünde ortalama OSKÇ 4,4±0,32 mm idi. Sonuç: USG ile OSKÇ ölçümü, DKA’lı çocuklarda BÖ’yü tahmin etmek için destekleyici bir yöntem olabilir.

Keywords

Diyabetik ketoasidoz, optik sinir kılıf çapı ölçümü, beyin ödemi

CAN BRAIN EDEMA BE PREDICTED WITH OPTIC NERVE SHEATH DIAMETER MEASUREMENT IN CASES WITH DIABETIC KETOACIDOSIS?: A PRELIMINARY STUDY

Abstract

Objective: The clinical signs and symptoms of brain edema resulting from diabetic ketoacidosis (DKA) may not always be ob vious. When the intracranial pressure increases, the optic nerve sheath diameter (ONSD) simultaneously increases and can be imaged with ultrasonography. We aimed to discuss the determinative features of ONSD measurements in brain edema (BE) in DKA. Materials and Methods: Patients who were classified as having mild, moderate and severe DKA were included in the study. Transorbital ultrasonography was performed during the first two hours of treatment while the patients remained in the supine neutral position with their eyes closed. The optic nerve sheath diameters, which appeared as a hypoechoic double-edged line 3 mm deep to the globe, were measured. The same measurements were repeated in outpatient clinic controls. The ONSD values and metabolic, neurological conditions of the patients were compared. Results: Eight patients with a mean age of 8.8±3 (Standard Deviation (SD)) years were included in the study. Seven of them presented with moderate to severe DKA. Two patients suffering from headaches were found to have mild BE according to the brain computerized tomography (CT). The ONSD was 5.7±0.93 mm (mean±SD) in the patients with moderate-severe DKA and 4 mm in the single patient with mild DKA. The ONSDs of the two patients with BE on the CT were 6.8 mm and 5.9 mm. The mean ONSD of the five patients with severe DKA was 4.4±0.32 mm in the outpatient clinic checks. Conclusion: The measurement of ONSD by USG may be a supportive method for predicting BE in children with DKA.

Keywords

Diabetic ketoacidosis, Optic nerve sheath diameter measurement, Brain edema.

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