TRANSIENT BENIGN HYPERPHOSPHATASEMIA DUE TO ROTAVIRUS GASTROENTERITIS

Year 2023, Volume: 86 Issue: 4, 402 - 405, 01.12.2023

Yasin Akkuş , Muharrem Çiçek , Melek Elma , Selen Baran Özmen , Özlem Kalaycık Şengül

https://doi.org/10.26650/IUITFD.1281081

Abstract

Transient benign hyperphosphatasemia (TBH) is a benign condition characterized by transiently elevated serum alkaline phosphatase (ALP) levels by 3-50 times normal values. It can sometimes be seen in connection with different clinical disorders such as respiratory tract infections, gastrointestinal diseases, congenital metabolic disorders, malignancies, congenital anomalies, anemia, and neurological disorders. In this report, we describe three children who had TBH after rotavirus-associated gastroenteritis and in whom there was no evidence of liver or bone disease. We aim to raise awareness and draw attention to TBH in this case report.

Keywords

Transient hyperphosphatasemia, alkaline phosphatase, rotavirus, gastroenteritis, children

Project Number

yok

ROTAVİRÜS GASTROENTERİTİNE BAĞLI GEÇİCİ BENİGN HİPERFOSFATAZEMİ

Abstract

Geçici benign hiperfosfatazemi (TBH), serum alkalen fosfataz (ALP) düzeylerinin normalin 3-50 katı kadar geçici olarak yükselmesi ile karakterize ve bazen de gastrointestinal hastalıklar, solunum yolu enfeksiyonları, doğumsal anomaliler, doğumsal metabolik bozukluklar, anemi, maligniteler, nörolojik bozukluklar gibi farklı klinik bozukluklarla birlikte görülebilmektedir. Bu çalışmada, karaciğer veya kemik hastalığı olmayan, rotavirüs ile ilişkili gastroenterit sonrası TBH'li üç çocuk sunuldu. Bu olguların sunulması ile TBH konusuna dikkat çekilmesi ve farkındalık yaratılması amaçlandı.

Keywords

Geçici hiperfosfatazemi, alkalin fosfataz, rotavirüs, gastroenterit, çocukluk evresi

Supporting Institution

yok

Project Number

yok

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