Year 2008,
Volume: 71 Issue: 3, 88 - 90, 14.11.2011
Abstract
Akromegali, iskemik kalp hastalığı için bilinen bir risk faktörüdür. Adrenal adenom ile birlikte idrar katekolaminlerinde artış olması durumunda feokromositoma ihtimali oldukça yüksektir. Bununla birlikte, iskemik kalp hastalığına bağlı olarak da idrar katekolaminlerinde artış ortaya çıkabilir. Yazımızda, akromegalinin klasik özelliklerini barındıran ve iskemik kalp hastalığı olan bir olgu sunmaktayız. Olgumuzda posteroanterior akciğer grafisinde saptanan parakardiyak opasitenin incelenmesi için çekilen toraks bilgisayarlı tomografisinde (BT) bir adrenal adenom tespit edilmiş ve idrar katekolamin seviyeleri yüksek bulunmuştur. Koroner arter by-pass greft operasyonu sonrasında idrar katekolamin seviyeleri normale dönmüştür. İdrar katekolaminleri yüksek bulunduğunda, klinik olarak feokromositoma ihtimali düşük ise, iskemik kalp hastalığı gibi sempatik aktivasyonun bulunduğu durumlar akla getirilmeli ve feokromositoma tanısı konulmadan önce bu durumlar dışlanmalıdır.
References
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- Kudva YC, Young Jr WF, Thompson GB, Grant CS, van He- erden JA Adrenal incidentaloma: an important component of the clinical presentation spectrum of benign sporadic adrenal pheochromocytoma. Endocrinologist 1999; 9: 77- 80
- Lee DD, Kimura S, DeQuattro V. Noradrenergic activity and silent ischaemia in hypertensive patients with stable angina: effect of metoprolol. Lancet 1989; 1: 403- 406.
- Page LB, Raker JW, Berberich FR. Pheochromocytoma with predominant epinephrine secretion. Am J Med 1969; 47: 648- 652.
- Sasaki A, Yumita S, Kimura S, Miura Y, Yoshinaga K. Im- munoreactive corticotropin-releasing hormone, growth hor- mone-releasing hormone, somatostatin, and peptide histidi- ne methionine are present in adrenal pheochromocytomas, but not in extra-adrenal pheochromocytoma. J Clin Endocri- nol Metab 1990; 70: 996- 999.
- Sleilati GG, Kovacs KT, Honasoge M. Acromegaly and phe- ochromocytoma: report of a rare coexistence. Endocr Pract 2002; 8: 54-60.
- Vitale G, Pivonello R, Lombardi G, Colao A. Cardiovascu- lar complications in acromegaly. Minerva Endocrinol 2004; 29: 77- 88.
Year 2008,
Volume: 71 Issue: 3, 88 - 90, 14.11.2011
Abstract
References
- Baughan J, de Gara C, Morrish D. A rare association betwe- en acromegaly and pheochromocytoma. Am J Surg 2001; 182: 185- 187.
- Bryant J, Farmer J, Kessler LJ, Townsend RR, Nathanson KL. Pheochromocytoma: the expanding genetic differential diagnosis. J Natl Cancer Inst 2003; 95: 1196- 1204.
- Carlsson L, Abrahamsson T, Almgren O. Release of norad- renaline in myocardial ischemia--importance of local inacti- vation by neuronal and extraneuronal mechanisms. J Cardi- ovasc Pharmacol 1986; 8: 545-553.
- Crout JR, Sjoerdsma A Turnover and metabolism of catecho- lamine in patients with pheochromocytoma. J Clin Invest 1964; 43: 94- 102
- Eisenhofer G, Goldstein DS, Walther MM, Friberg P, Len- ders JW, Keiser HR, Pacak K Biochemical diagnosis of phe- ochromocytoma: how to distinguish true- from false-positi- ve test results. J Clin Endocrinol Metab 2003; 88: 2656- 2666.
- Goldstein RE, O’Neill JA Jr, Holcomb GW 3rd, Morgan WM 3rd, Neblett WW 3rd, Oates JA, Brown N, Nadeau J, Smith B, Page DL, Abumrad NN, Scott HW Jr. Clinical ex- perience over 48 years with pheochromocytoma. Ann Surg 1999; 229: 755- 764.
- Kudva YC, Young Jr WF, Thompson GB, Grant CS, van He- erden JA Adrenal incidentaloma: an important component of the clinical presentation spectrum of benign sporadic adrenal pheochromocytoma. Endocrinologist 1999; 9: 77- 80
- Lee DD, Kimura S, DeQuattro V. Noradrenergic activity and silent ischaemia in hypertensive patients with stable angina: effect of metoprolol. Lancet 1989; 1: 403- 406.
- Page LB, Raker JW, Berberich FR. Pheochromocytoma with predominant epinephrine secretion. Am J Med 1969; 47: 648- 652.
- Sasaki A, Yumita S, Kimura S, Miura Y, Yoshinaga K. Im- munoreactive corticotropin-releasing hormone, growth hor- mone-releasing hormone, somatostatin, and peptide histidi- ne methionine are present in adrenal pheochromocytomas, but not in extra-adrenal pheochromocytoma. J Clin Endocri- nol Metab 1990; 70: 996- 999.
- Sleilati GG, Kovacs KT, Honasoge M. Acromegaly and phe- ochromocytoma: report of a rare coexistence. Endocr Pract 2002; 8: 54-60.
- Vitale G, Pivonello R, Lombardi G, Colao A. Cardiovascu- lar complications in acromegaly. Minerva Endocrinol 2004; 29: 77- 88.
There are 12 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Case Reports |
| Authors | |
| Publication Date | November 14, 2011 |
| Submission Date | November 14, 2011 |
| Published in Issue | Year 2008 Volume: 71 Issue: 3 |
Cite
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