Year 2004,
Volume: 4 Issue: 1, 1091 - 1104, 28.12.2011
Abstract
In this paper, we investigate dynamics of voltage-gated ionic channels which are of great importance in integrating the information received by neurons. Understanding of dynamical behavior of voltage-gated ionic channels plays a major role for determining underlying mechanism of spike activity and predicting the neuronal behavior. Investigation is carried out based on Hodgkin-Huxley (H-H) mathematical formalism. Ionic channel gate model is discussed briefly. Relaxation phenomenon is studied in the gate variables. Then effects of temperature on dynamics of gate variables are examined. Finally voltage-clamped simulations are carried out to determine their dynamic behaviors based on squid giant axon.
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Details
| Primary Language | English |
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| Authors | |
| Publication Date | December 28, 2011 |
| Published in Issue | Year 2004 Volume: 4 Issue: 1 |