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QUANTITATIVE DETABWLINATION OF α- AMANITIN BY HPLC IN AMANlTA PHALLOIDES GROWING IN ISTANBUL FORESTS

Year 1995, Volume: 31 , 17 - 24, 09.09.2015

A. Mat1, T. Yurdun2, Z. Tümkor1

Abstract

In Turkey, mushroom poisonings are frequent especially in autumn and spring. In recent years, a great number of mushroom poisoning cases have been reported in fstanbul. Excursions to forests in fstanbul and its surroundings evidenced the widespread growth of Amanita phalloides in large numbers. The amount of α-amanitin was determined by HPLC in samples collected in 1991 and 1992.The a-amanitin content is between 4.4-13.3 mg/100 g in fresh mushrooms. Humidity and temperature are the most important factors affecting the amatoxin content in mushrooms.

Key words: Amanita phalloides, α-amanitin, Mushroom poisoning, HPLC.

Keywords

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References

  • 1. Baytop, T., Tiirkiye'de Zehirli Bitkiler, Bitki Zehirlenmeleri ve Tedavi Yontemleri, p. 61, i.u.~ay. NO. 3560, istanbul(1989).
  • 2. Bresinsky, A., Besl,H., A Colour Atlas of Poisonous Fungi, p..,19, Wolfe Publishing Ltd. London (1990).
  • 3. Wieland, T., Peptides of Poisonous Amanita Mushrooms, p.13, Springer-Verlag, New York (1986).
  • 4. Tyler, V. E. Jr., Benedict, R. G., Brady, L. R., Robbers, J. E., J. Pharmacol. Sci. 55: 590- 593 (1966).
  • 5. Faulstich,H., Georgopoulos,D., Bloching, M., Wieland, T., Z. Naturforsch. 29: 86-88 (1974).
  • 6. Yocum R.R., Simons, D.M., Lloydia 40: 178-190 (1977).
  • 7. Andary,C., Enjalbert, F., Privat,G., Mandrou,B., J.Cliromatogr. 132: 525-532 0977).
  • 8. Andary, C., Enjalbert, F., Privat, G., Mandrou, B., Bull. Soc. Myc. Fr. 95: 169-180 (1979).
  • 9. Andary, C., Privat, G., Enjalbert, F., Mandrou, B., Documents Mycologiques 10: 61-69 (1979).
  • 10. Stijve, T., Seeger,R., Z. Naturforsch. 34: 1133-1138 (1979)
  • 11. Beutler, J.A., Der Marderosian, A.H., J.Nat.Prod. 44: 422-431 (1981).
  • 12. Miiderrisoglu, C., Karakullukqu, F., Orak, E., Beydilli, A., Mat, A., Tik TIP Demea Dergisi 58: 1-1 1 (1992).
  • 13. Yafet-Aji, D., Cahgkan, S., Nayu, A., Mat, A., Can, B., Yagar, Z., Ozgahin, H., Cullu, F., Sever, L., 1st. (;oc~ck Kli~z. Derg. 27: 51-54 (1992).

QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH'OIIPES GROWING IN ISTANBUL FORESTS

Year 1995, Volume: 31 , 17 - 24, 09.09.2015

A. Mat1, T. Yurdun2, Z. Tümkor1

Abstract

In Turkey, mushroom poisonings are frequent especially in mtumn and
spring. ,In recent years, a great number of mushroom poisoning cases have been
reported in fstanbul. Excursions to forests in fstanbul and its surroundings evidenced the widespread growth of Amanita phalloides in large numbers. The
amount of a-amanitin was determined by HPLC in samples collected in 1991
and 1992.The a-amanitin content is between 4.4-13.3 mg/100 g in fresh mushrooms. Humidity and temperature are the most important factors affecting the
amatoxin content in mushrooms

Keywords

Amanita phalloides a-amanitin Mushroom poisoning HPLC

References

  • 1. Baytop, T., Tiirkiye'de Zehirli Bitkiler, Bitki Zehirlenmeleri ve Tedavi Yontemleri, p. 61, i.u.~ay. NO. 3560, istanbul(1989).
  • 2. Bresinsky, A., Besl,H., A Colour Atlas of Poisonous Fungi, p..,19, Wolfe Publishing Ltd. London (1990).
  • 3. Wieland, T., Peptides of Poisonous Amanita Mushrooms, p.13, Springer-Verlag, New York (1986).
  • 4. Tyler, V. E. Jr., Benedict, R. G., Brady, L. R., Robbers, J. E., J. Pharmacol. Sci. 55: 590- 593 (1966).
  • 5. Faulstich,H., Georgopoulos,D., Bloching, M., Wieland, T., Z. Naturforsch. 29: 86-88 (1974).
  • 6. Yocum R.R., Simons, D.M., Lloydia 40: 178-190 (1977).
  • 7. Andary,C., Enjalbert, F., Privat,G., Mandrou,B., J.Cliromatogr. 132: 525-532 0977).
  • 8. Andary, C., Enjalbert, F., Privat, G., Mandrou, B., Bull. Soc. Myc. Fr. 95: 169-180 (1979).
  • 9. Andary, C., Privat, G., Enjalbert, F., Mandrou, B., Documents Mycologiques 10: 61-69 (1979).
  • 10. Stijve, T., Seeger,R., Z. Naturforsch. 34: 1133-1138 (1979)
  • 11. Beutler, J.A., Der Marderosian, A.H., J.Nat.Prod. 44: 422-431 (1981).
  • 12. Miiderrisoglu, C., Karakullukqu, F., Orak, E., Beydilli, A., Mat, A., Tik TIP Demea Dergisi 58: 1-1 1 (1992).
  • 13. Yafet-Aji, D., Cahgkan, S., Nayu, A., Mat, A., Can, B., Yagar, Z., Ozgahin, H., Cullu, F., Sever, L., 1st. (;oc~ck Kli~z. Derg. 27: 51-54 (1992).
There are 13 citations in total.

Details

Primary Language English
Subjects Pharmacology and Pharmaceutical Sciences
Journal Section Makaleler
Authors

A. Mat1, T. Yurdun2, Z. Tümkor1 This is me

Publication Date September 9, 2015
Published in Issue Year 1995 Volume: 31

Cite

APA Z. Tümkor1, A. M. T. Y. (2015). QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS. Journal of Faculty of Pharmacy of Istanbul University, 31, 17-24.
AMA Z. Tümkor1 AMTY. QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS. Journal of Faculty of Pharmacy of Istanbul University. September 2015;31:17-24.
Chicago Z. Tümkor1, A. Mat1, T. Yurdun2,. “QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS”. Journal of Faculty of Pharmacy of Istanbul University 31, September (September 2015): 17-24.
EndNote Z. Tümkor1 AMTY (September 1, 2015) QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS. Journal of Faculty of Pharmacy of Istanbul University 31 17–24.
IEEE A. M. T. Y. Z. Tümkor1, “QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS”, Journal of Faculty of Pharmacy of Istanbul University, vol. 31, pp. 17–24, 2015.
ISNAD Z. Tümkor1, A. Mat1, T. Yurdun2,. “QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS”. Journal of Faculty of Pharmacy of Istanbul University 31 (September 2015), 17-24.
JAMA Z. Tümkor1 AMTY. QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS. Journal of Faculty of Pharmacy of Istanbul University. 2015;31:17–24.
MLA Z. Tümkor1, A. Mat1, T. Yurdun2,. “QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS”. Journal of Faculty of Pharmacy of Istanbul University, vol. 31, 2015, pp. 17-24.
Vancouver Z. Tümkor1 AMTY. QUANTITATIVE DETABWLINATION OF a - AMANHYN BY BPLC IN AMANlTA PH’OIIPES GROWING IN ISTANBUL FORESTS. Journal of Faculty of Pharmacy of Istanbul University. 2015;31:17-24.