Chemical characterization of Glaucosciadium cordifolium (Boiss.) B. L. Burtt & P. H. Davis essential oils and their antimicrobial, and antioxidant activities

Year 2019, Volume: 49 Issue: 2, 77 - 80, 01.08.2019

Ayşe Esra Karadağ Betül Demirci Ömer Çeçen Fatma Tosun

Abstract

DOI: 10.26650/IstanbulJPharm.2019.19013

Chemical composition of volatile oils
obtained from the roots, fruits and aerial parts of Glaucosciadium cordifolium
(Boiss.) B.L.  Burtt&P.H. Davis
(Apiaceae) were analyzed using gas chromatography-flame ionization
detector/mass spectrometry, simultaneously. Furthermore, antimicrobial and
antioxidant activities of G. cordifolium volatile oils were investigated for
possible utilization.  Total of 62
volatile compounds were identified in G. cordifolium essential oils, where the
main component was characterized as α-pinene in all parts, commonly. The other
main components were β-pinene (15.7%), (Z)-β-ocimene (14%) and sabinene (7%) in
the volatile oil of the aerial part; sabinene (10.1%), β-pinene (10.1%) and
α-phellandrene (5.3%) in the essential oil of the fruits; hexadecane (12.2%),
tetradecane (11.9%), octadecane (7.4%) in the essential oil obtained from the
root, respectively.  The in vitro microdilution
method was used for the antimicrobial activity testing against Salmonella typhi
ATCC 6539, Acinetobacter baumanii ATCC 19606, Bacillus cereus ATCC 14579,
Staphylococcus aereus ATCC 6538, Listeria monocytogenes ATCC 19115,
Helicobacter pylori ATCC 43504 and Mycobacterium avium ATCC 25291. The best
antimicrobial activity of the volatile oils was against L. monocytogenes among
the tested microorganisms. In addition, DPPH•-ABTS• scavenging activity was
tested, none of the essential oils showed any significant antioxidant activity.  

Cite this article as: Karadağ AE, Demirci
B, Çeçen Ö, Tosun F (2019). Chemical characterization of Glaucosciadium
cordifolium (Boiss.) B. L.  Burtt &
P. H. Davis essential oils and their antimicrobial, and antioxidant activities.
Istanbul J Pharm 49 (2): 77-80.

Keywords

Apiaceae, Glaucosciadium cordifolium, antimicrobial, antioxidant, gas chromatography, mass spectrometry

References

• Baser KHC, Özek T, Demirci B, Duman H (2000). Composition of the essential oil of Glaucosciadium cordifolium (Boiss.) Burtt et Davis from Turkey. Flavour Fragr J 15: 45-46. Blois MS (1958). Antioxidant determinations by the use of a stable free radical. Nature 181: 1199-1200. Chung GA, Aktar Z, Jackson S, Duncan K (1995). High-Throughput Screen for Detecting Antimycobacterial Agents. Antimicrob Agents Chemother 39: 2235-8. Clinical and Laboratory Standards Institute M7-A7 (2006). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard-Seventh Edition, Wayne, Pa. USA. Clinical and Laboratory Standards Institute (2003). Susceptibility testing of Mycobacteria, Norcardiae, and Other Aerobic Actinomycetes; Approved Standard. CLSI document M24-A. Wayne, Pa. USA. Davis PH (1982). Flora of Turkey and the East Aegean Islands, Edinburgh, UK: Edinburgh University Press, Vol. 4; pp. 514. ESO 2000 (1999). The Complete Database of Essential Oils, Boelens Aroma Chemical Information Service, The Netherlands. EUCAST clinical breakpoints for Helicobacter pylori, European Committee on Antimicrobial Susceptibility Testing: 2011. Lee SM, Kim J, Jeong J, Park YK, Bai G, Lee EY (2007). Evaluation of the Broth Microdilution Method Using 2,3-Diphenyl-5- thienyl-(2)-tetrazolium Chloride for Rapidly Growing Mycobacteria Susceptibility Testing. J Korean Med Sci 22: 784-90. Okur ME, Ayla Ş, Çiçek Polat D, Günal MY, Yoltaş A, Biçeroğlu Ö (2018). Novel insight into wound healing properties of methanol extract of Capparis ovata Desf. var. palaestina Zohary fruits. J Pharm Pharmacol 70: 1401-1413. Özhatay N, Koçak S (2011). Plants used for medicinal purposes in Karaman Province (Southern Turkey). Istanbul J Pharm 41: 75-89. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999). Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Rad Biol Med 26: 1231-1237. Whitmire JM, Merrell DS (2012). Successful culture techniques for Helicobacter species: general culture techniques for Helicobacter pylori. Methods Mol Biol 921: 17-27.