Research Article
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Aromatherapeutic essential oils and their pharmaceutical combinations: Tools for inhibition of quorum sensing activity and biofilm formation of human pathogens*

Year 2022, Volume: 52 Issue: 1, 54 - 63, 28.04.2022
https://doi.org/10.26650/IstanbulJPharm.2022.998774

Abstract

Background and Aims: Aromatherapy, as one of the complementary therapies, uses essential oils as the main therapeutic agents to treat several diseases. In the present study, it was aimed to investigate inhibition of quorum sensing (QS) and bio- film formation of aromatherapeutic essential oils (AEOs) and their pharmaceutical combinations (PC-I and PC-II).
Methods: The anti-QS potential of AEOs were determined using the biosensor strains Chromobacterium violaceum ATCC 12472 and Pseudomonas aeruginosa PAO1. Anti-QS activity was detected by agar-well diffusion and violacein pigment inhi- bition assays. Blocking of PAO1 swim and swarm motilities and biofilm formation was also performed.
Results: Most of the AEOs demonstrated highly active (>95%) violacein pigment inhibition. Additionally, they inhibited swarming (40.34%-72.80%) and swimming (20.06%-50.08%) motilities of PAO1. Moreover, the majority of AEOs also de- creased the biofilm formation, particularly on P. aeruginosa and S. aureus.
Conclusion: Consequently, aromatherapeutic formulations might be a complementary or prophylactic cure for infectious dis- ease by their anti-QS and antibiofilm activities rather than just antimicrobial effects.

Supporting Institution

Gazi Üniversitesi

Project Number

02/2019-12

Thanks

This work was performed as a part of Müjgan Özfenerci’s Master of Science thesis and supported by the Scientific Research Projects Unit of Gazi University, Ankara-Turkey Grant number: 02/2019-12.

References

  • Ahmad, A., Viljoen, A., & Chenia, H. (2015). The impact of plant volatiles on bacterial quorum sensing. Letters in Applied Microbiol- ogy, 60(1), 8-19. https://doi.org/10.1111/lam.12343
  • Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar,F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611. https:// doi.org/10.1016/j.apjtb.2015.05.007
  • Alibi, S., Selma, W. B., Ramos-Vivas, J., Smach, M. A., Touati, R., Boukadida, J., Navas, J. & Mansour, H. B. (2020). Anti-oxidant, anti- bacterial, anti-biofilm, and anti-quorum sensing activities of four essential oils against multidrug-resistant bacterial clinical isolates. Current Research in Translational Medicine, 68(2), 59-66.https://doi. org/10.1016/j.retram.2020.01.001
  • Bai A, J., & Vittal, R. R. (2014). Quorum sensing inhibitory and anti- biofilm activity of essential oils and their in vivo efficacy in food systems. Food Biotechnology, 28(3), 269-292. https://doi.org/10.1 080/08905436.2014.932287
  • Bharti, S. K., Pathak, V., Alam, T., Arya, A., Singh, V. K., Verma, A. K., & Rajkumar, V. (2020). Materialization of novel composite bio‐based active edible film functionalized with essential oils on antimicro- bial and antioxidative aspect of chicken nuggets during extend- ed storage. Journal of Food Science, 85(9), 2857-2865. https://doi. org/10.1111/1750-3841.15365
  • Blosser, R. S., & Gray, K. M. (2000). Extraction of violacein from Chromobacterium violaceum provides a new quantitative bioas- say for N-acyl homoserine lactone autoinducers. Journal of Micro- biological Methods, 40(1), 47-55. https://doi.org/10.1016/S0167- 7012(99)00136-0
  • Boire, N. A., Riedel, S., & Parrish, N. M. (2013). Essential oils and future antibiotics: new weapons against emerging ‘superbugs’. Journal of Ancient Diseases & Preventive Remedies, 1(2), 1000105. https://doi.org/10.4172/jadpr.1000105
  • Brun, P., Bernabè, G., Filippini, R., & Piovan, A. (2019). In vitro anti- microbial activities of commercially available tea tree (Melaleuca alternifolia) essential oils. Current Microbiology, 76(1), 108-116. https://doi.org/10.1007/s00284-018-1594-x.
  • Bali, E. B., Erkan Türkmen, K. , Erdönmez, D., & Sağlam, N. (2019). Comparative study of inhibitory potential of dietary phytochemi- cals against quorum sensing activity of and biofilm formation by Chromobacterium violaceum 12472, and swimming and swarm- ing behaviour of Pseudomonas aeruginosa PAO1. Food Technol- ogy and Biotechnology, 57(2), 212-221. https://doi.org/10.17113/ ftb.57.02.19.5823
  • Cáceres, M., Hidalgo, W., Stashenko, E., Torres, R., & Ortiz, C. (2020). Essential oils of aromatic plants with antibacterial, anti-biofilm and anti-quorum sensing activities against pathogenic bacteria. Antibiotics, 9(4), 147. https://doi.org/10.3390/antibiotics9040147
  • Doğan, Ş., Gökalsın, B., Şenkardeş, İ., Doğan, A., & Sesal, N. C. (2019). Anti- quorum sensing and anti-biofilm activities of Hypericum perforatum extracts against Pseudomonas aeruginosa. Journal of Ethnopharmacol- ogy, 235, 293-300. https://doi.org/10.1016/j.jep.2019.02.020
  • Eris, R., & Ulusoy, S. (2013). Rose, clove, chamomile essential oils and pine turpentine inhibit quorum sensing in Chromobacterium violaceum and Pseudomonas aeruginosa. Journal of Essential Oil Bearing Plants, 16(2), 126-135. https://doi.org/10.1080/097206 0X.2013.794026
  • Husain, F. M., Ahmad, I., Khan, M. S., Ahmad, E., Tahseen, Q., Khan,M. S., & Alshabib, N. A. (2015). Sub-MICs of Mentha piperita essen- tial oil and menthol inhibits AHL mediated quorum sensing and biofilm of Gram-negative bacteria. Frontiers in Microbiology, 6, 420. https://doi.org/10.3389/fmicb.2015.00420
  • Ilic-Tomić, T., Soković, M., Vojnović, S., Ćirić, A. D., Veljić, M., Nikodinović-Runić, J., & Novaković, M. M. (2017). Diarylheptanoids from Alnus viridis ssp viridis and Alnus glutinosa: Modulation of Quorum Sensing Activity in Pseudomonas aeruginosa. Planta med- ica, 83(01-02), 117-125. https://doi.org/10.1055/s-0042-107674
  • Kavanaugh, N. L., & Ribbeck, K. (2012). Selected antimicrobial essential oils eradicate Pseudomonas spp. and Staphylococcus aureus biofilms. Applied and Environmental Microbiology, 78(11), 4057-4061. https://doi.org/10.1128/AEM.07499-11
  • Kerekes, E. B., Deák, É., Takó, M., Tserennadmid, R., Petkovits, T., Vágvölgyi, C., & Krisch, J. (2013). Anti‐biofilm forming and anti‐ quorum sensing activity of selected essential oils and their main components on food‐related micro‐organisms. Journal of Applied Microbiology, 115(4), 933-942. https://doi.org/10.1111/jam.12289
  • Li, S., Chen, S., Fan, J., Cao, Z., Ouyang, W., Tong, N., Hu, X., Hu, J., Li, P., Feng, Z. & Huang, X. (2018). Anti-biofilm effect of novel thiazole acid analogs against Pseudomonas aeruginosa through IQS path- ways. European Journal of Medicinal Chemistry, 145, 64-73. https:// doi.org/10.1016/j.ejmech.2017.12.076
  • Luís, Â., Duarte, A., Gominho, J., Domingues, F., & Duarte, A. P. (2016). Chemical composition, antioxidant, antibacterial and anti- quorum sensing activities of Eucalyptus globulus and Eucalyptus radiata essential oils. Industrial Crops and Products, 79, 274-282. https://doi.org/10.1016/j.indcrop.2015.10.055
  • Merghni, A., Noumi, E., Hadded, O., Dridi, N., Panwar, H., Ceylan, O., Mastouri, M. & Snoussi, M. (2018). Assessment of the antibiofilm and antiquorum sensing activities of Eucalyptus globulus essen- tial oil and its main component 1, 8-cineole against methicillin- resistant Staphylococcus aureus strains. Microbial Pathogenesis, 118, 74-80. https://doi.org/10.1016/j.micpath.2018.03.006
  • Mokhetho, K. C., Sandasi, M., Ahmad, A., Kamatou, G. P., & Viljoen,A. M. (2018). Identification of potential anti-quorum sensing com- pounds in essential oils: A gas chromatography-based metabo- lomics approach. Journal of Essential Oil Research, 30(6), 399-408. https://doi.org/10.1080/10412905.2018.1503100
  • Mukherji, R., & Prabhune, A. (2014). Novel glycolipids synthesized using plant essential oils and their application in quorum sensing inhibition and as antibiofilm agents. The Scientific World Journal, 2014. https://doi.org/10.1155/2014/890709
  • O’Toole, G. A., & Kolter, R. (1998). Initiation of biofilm forma- tion in Pseudomonas fluorescens WCS365 proceeds via mul- tiple, convergent signalling pathways: a genetic analysis. Molecular Microbiology, 28(3), 449-461. https://doi.org/10.1046/ j.1365-2958.1998.00797.x
  • Oh, S., Yun, W., Lee, J., Lee, C., Kwak, W., & Cho, J. (2017). Effects of es- sential oil (blended and single essential oils) on anti-biofilm forma- tion of Salmonella and Escherichia coli. Journal of Animal Science and Technology, 59(1), 1-5. https://doi.org/10.1186/s40781-017-0127-7
  • Önem, E., Tüzün, B., & Akkoç, S. (2021). Anti-quorum sensing activ- ity in Pseudomonas aeruginos a PA01 of benzimidazolium salts: electronic, spectral and structural investigations as theoretical approach. Journal of Biomolecular Structure and Dynamics, 1-12. https://doi.org/10.1080/07391102.2021.1890222
  • Packiavathy, I. A. S. V., Agilandeswari, P., Musthafa, K. S., Pandian, S. K., & Ravi, A. V. (2012). Antibiofilm and quorum sensing inhibitory potential of Cuminum cyminum and its secondary metabolite methyl eugenol against Gram negative bacterial pathogens. Food Research Interna- tional, 45(1), 85-92. https://doi.org/10.1016/j.foodres.2011.10.022
  • Pellegrini, M. C., Alvarez, M. V., Ponce, A. G., Cugnata, N. M., De Piano, F. G., & Fuselli, S. R. (2014). Anti-quorum sensing and antimi- crobial activity of aromatic species from South America. Journal of Essential Oil Research, 26(6), 458-465. https://doi.org/10.1080/1 0412905.2014.947387
  • Raut, J. S., & Karuppayil, S. M. (2014). A status review on the me- dicinal properties of essential oils. Industrial Crops and Products, 62, 250-264. https://doi.org/10.1016/j.indcrop.2014.05.055
  • Tariq, S., Wani, S., Rasool, W., Shafi, K., Bhat, M. A., Prabhakar, A., Shalla, A.H. & Rather, M.A. (2019). A comprehensive review of the antibacterial, antifungal and antiviral potential of essential oils and their chemical constituents against drug-resistant micro- bial pathogens. Microbial Pathogenesis, 134, 103580.https://doi. org/10.1016/j.micpath.2019.103580
  • Vasavi, H. S., Arun, A. B., & Rekha, P. D. (2014). Anti-quorum sensing activity of Psidium guajava L. flavonoids against Chromobacterium violaceum and Pseudomonas aeruginosa PAO1. Microbiology and Im- munology, 58(5), 286-293. https://doi.org/10.1111/1348-0421.12150
  • Vieira, M., Bessa, L. J., Martins, M. R., Arantes, S., Teixeira, A. P., Mendes, Â., Martins da Costa, P. & Belo, A. D. (2017). Chemical composition, antibacterial, antibiofilm and synergistic proper- ties of essential oils from Eucalyptus globulus Labill. and seven Mediterranean aromatic plants. Chemistry & Biodiversity, 14(6), e1700006. https://doi.org/10.1002/cbdv.201700006
  • Vipin, C., Mujeeburahiman, M., Ashwini, P., Arun, A., & Rekha, P.
  • D. (2019). Anti‐biofilm and cytoprotective activities of quercetin against Pseudomonas aeruginosa isolates. Letters in Applied Mi- crobiology, 68(5), 464-471. https://doi.org/10.1111/lam.13129
  • Yan, M.-R., Wang, C.-H., Cruz Flores, N. J., & Su, Y.-Y. (2019). Targeting open market with strategic business innovations: a case study of growth dynamics in essential oil and aromatherapy industry. Journal of Open Innovation: Technology, Market, and Complexity, 5(1), 7. https://doi.org/10.3390/joitmc5010007
  • Yap, P. S. X., Yiap, B. C., Ping, H. C., & Lim, S. H. E. (2014). Essen- tial oils, a new horizon in combating bacterial antibiotic re- sistance. The Open Microbiology Journal, 8, 6. https://doi. org/10.2174/1874285801408010006
  • Zahin, M., Hasan, S., Aqil, F., Khan, M., Ahmad, S., Husain,F. M., & Ahmad, I. (2010). Screening of certain medicinal plants from India for their anti-quorum sensing activity. http://hdl.handle.net/123456789/10652
  • Zgoda, J., & Porter, J. (2001). A convenient microdilution method for screening natural products against bacteria and fungi. Pharmaceuti- cal Biology, 39(3), 221-225. https://doi.org/10.1076/phbi.39.3.221.5934
  • Zgurskaya, H. I., López, C. A., & Gnanakaran, S. (2015). Perme- ability barrier of Gram-negative cell envelopes and approaches to bypass it. ACS Infectious Diseases, 1(11), 512-522. https://doi. org/10.1021/acsinfecdis.5b00097
  • Zhang, D., Gan, R. Y., Zhang, J. R., Farha, A. K., Li, H. B., Zhu, F., Wang,X.H. & Corke, H. (2020). Antivirulence properties and related mechanisms of spice essential oils: A comprehensive review. Comprehensive Reviews in Food Science and Food Safety, 19(3), 1018-1055. https://doi.org/10.1111/1541-4337.12549
  • Zhang, Y., Djakpo, O., Xie, Y., Guo, Y., Yu, H., Cheng, Y., Qian, H., Shi,R. & Yao, W. (2019). Anti-quorum sensing of Galla chinensis and Coptis chinensis on bacteria. Lebensmittel-Wissenchaft und Tech- nologie, 101, 806-811. https://doi.org/10.1016/j.lwt.2018.11.090
  • Zhang, Y., Kong, J., Xie, Y., Guo, Y., Cheng, Y., Qian, H., & Yao, W. (2018). Essential oil components inhibit biofilm formation in Erwinia caroto- vora and Pseudomonas fluorescens via anti-quorum sensing activ- ity. Lebensmittel-Wissenchaft und Technologie, 92, 133-139. https://doi. org/10.1016/j.lwt.2018.02.027
Year 2022, Volume: 52 Issue: 1, 54 - 63, 28.04.2022
https://doi.org/10.26650/IstanbulJPharm.2022.998774

Abstract

Project Number

02/2019-12

References

  • Ahmad, A., Viljoen, A., & Chenia, H. (2015). The impact of plant volatiles on bacterial quorum sensing. Letters in Applied Microbiol- ogy, 60(1), 8-19. https://doi.org/10.1111/lam.12343
  • Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar,F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611. https:// doi.org/10.1016/j.apjtb.2015.05.007
  • Alibi, S., Selma, W. B., Ramos-Vivas, J., Smach, M. A., Touati, R., Boukadida, J., Navas, J. & Mansour, H. B. (2020). Anti-oxidant, anti- bacterial, anti-biofilm, and anti-quorum sensing activities of four essential oils against multidrug-resistant bacterial clinical isolates. Current Research in Translational Medicine, 68(2), 59-66.https://doi. org/10.1016/j.retram.2020.01.001
  • Bai A, J., & Vittal, R. R. (2014). Quorum sensing inhibitory and anti- biofilm activity of essential oils and their in vivo efficacy in food systems. Food Biotechnology, 28(3), 269-292. https://doi.org/10.1 080/08905436.2014.932287
  • Bharti, S. K., Pathak, V., Alam, T., Arya, A., Singh, V. K., Verma, A. K., & Rajkumar, V. (2020). Materialization of novel composite bio‐based active edible film functionalized with essential oils on antimicro- bial and antioxidative aspect of chicken nuggets during extend- ed storage. Journal of Food Science, 85(9), 2857-2865. https://doi. org/10.1111/1750-3841.15365
  • Blosser, R. S., & Gray, K. M. (2000). Extraction of violacein from Chromobacterium violaceum provides a new quantitative bioas- say for N-acyl homoserine lactone autoinducers. Journal of Micro- biological Methods, 40(1), 47-55. https://doi.org/10.1016/S0167- 7012(99)00136-0
  • Boire, N. A., Riedel, S., & Parrish, N. M. (2013). Essential oils and future antibiotics: new weapons against emerging ‘superbugs’. Journal of Ancient Diseases & Preventive Remedies, 1(2), 1000105. https://doi.org/10.4172/jadpr.1000105
  • Brun, P., Bernabè, G., Filippini, R., & Piovan, A. (2019). In vitro anti- microbial activities of commercially available tea tree (Melaleuca alternifolia) essential oils. Current Microbiology, 76(1), 108-116. https://doi.org/10.1007/s00284-018-1594-x.
  • Bali, E. B., Erkan Türkmen, K. , Erdönmez, D., & Sağlam, N. (2019). Comparative study of inhibitory potential of dietary phytochemi- cals against quorum sensing activity of and biofilm formation by Chromobacterium violaceum 12472, and swimming and swarm- ing behaviour of Pseudomonas aeruginosa PAO1. Food Technol- ogy and Biotechnology, 57(2), 212-221. https://doi.org/10.17113/ ftb.57.02.19.5823
  • Cáceres, M., Hidalgo, W., Stashenko, E., Torres, R., & Ortiz, C. (2020). Essential oils of aromatic plants with antibacterial, anti-biofilm and anti-quorum sensing activities against pathogenic bacteria. Antibiotics, 9(4), 147. https://doi.org/10.3390/antibiotics9040147
  • Doğan, Ş., Gökalsın, B., Şenkardeş, İ., Doğan, A., & Sesal, N. C. (2019). Anti- quorum sensing and anti-biofilm activities of Hypericum perforatum extracts against Pseudomonas aeruginosa. Journal of Ethnopharmacol- ogy, 235, 293-300. https://doi.org/10.1016/j.jep.2019.02.020
  • Eris, R., & Ulusoy, S. (2013). Rose, clove, chamomile essential oils and pine turpentine inhibit quorum sensing in Chromobacterium violaceum and Pseudomonas aeruginosa. Journal of Essential Oil Bearing Plants, 16(2), 126-135. https://doi.org/10.1080/097206 0X.2013.794026
  • Husain, F. M., Ahmad, I., Khan, M. S., Ahmad, E., Tahseen, Q., Khan,M. S., & Alshabib, N. A. (2015). Sub-MICs of Mentha piperita essen- tial oil and menthol inhibits AHL mediated quorum sensing and biofilm of Gram-negative bacteria. Frontiers in Microbiology, 6, 420. https://doi.org/10.3389/fmicb.2015.00420
  • Ilic-Tomić, T., Soković, M., Vojnović, S., Ćirić, A. D., Veljić, M., Nikodinović-Runić, J., & Novaković, M. M. (2017). Diarylheptanoids from Alnus viridis ssp viridis and Alnus glutinosa: Modulation of Quorum Sensing Activity in Pseudomonas aeruginosa. Planta med- ica, 83(01-02), 117-125. https://doi.org/10.1055/s-0042-107674
  • Kavanaugh, N. L., & Ribbeck, K. (2012). Selected antimicrobial essential oils eradicate Pseudomonas spp. and Staphylococcus aureus biofilms. Applied and Environmental Microbiology, 78(11), 4057-4061. https://doi.org/10.1128/AEM.07499-11
  • Kerekes, E. B., Deák, É., Takó, M., Tserennadmid, R., Petkovits, T., Vágvölgyi, C., & Krisch, J. (2013). Anti‐biofilm forming and anti‐ quorum sensing activity of selected essential oils and their main components on food‐related micro‐organisms. Journal of Applied Microbiology, 115(4), 933-942. https://doi.org/10.1111/jam.12289
  • Li, S., Chen, S., Fan, J., Cao, Z., Ouyang, W., Tong, N., Hu, X., Hu, J., Li, P., Feng, Z. & Huang, X. (2018). Anti-biofilm effect of novel thiazole acid analogs against Pseudomonas aeruginosa through IQS path- ways. European Journal of Medicinal Chemistry, 145, 64-73. https:// doi.org/10.1016/j.ejmech.2017.12.076
  • Luís, Â., Duarte, A., Gominho, J., Domingues, F., & Duarte, A. P. (2016). Chemical composition, antioxidant, antibacterial and anti- quorum sensing activities of Eucalyptus globulus and Eucalyptus radiata essential oils. Industrial Crops and Products, 79, 274-282. https://doi.org/10.1016/j.indcrop.2015.10.055
  • Merghni, A., Noumi, E., Hadded, O., Dridi, N., Panwar, H., Ceylan, O., Mastouri, M. & Snoussi, M. (2018). Assessment of the antibiofilm and antiquorum sensing activities of Eucalyptus globulus essen- tial oil and its main component 1, 8-cineole against methicillin- resistant Staphylococcus aureus strains. Microbial Pathogenesis, 118, 74-80. https://doi.org/10.1016/j.micpath.2018.03.006
  • Mokhetho, K. C., Sandasi, M., Ahmad, A., Kamatou, G. P., & Viljoen,A. M. (2018). Identification of potential anti-quorum sensing com- pounds in essential oils: A gas chromatography-based metabo- lomics approach. Journal of Essential Oil Research, 30(6), 399-408. https://doi.org/10.1080/10412905.2018.1503100
  • Mukherji, R., & Prabhune, A. (2014). Novel glycolipids synthesized using plant essential oils and their application in quorum sensing inhibition and as antibiofilm agents. The Scientific World Journal, 2014. https://doi.org/10.1155/2014/890709
  • O’Toole, G. A., & Kolter, R. (1998). Initiation of biofilm forma- tion in Pseudomonas fluorescens WCS365 proceeds via mul- tiple, convergent signalling pathways: a genetic analysis. Molecular Microbiology, 28(3), 449-461. https://doi.org/10.1046/ j.1365-2958.1998.00797.x
  • Oh, S., Yun, W., Lee, J., Lee, C., Kwak, W., & Cho, J. (2017). Effects of es- sential oil (blended and single essential oils) on anti-biofilm forma- tion of Salmonella and Escherichia coli. Journal of Animal Science and Technology, 59(1), 1-5. https://doi.org/10.1186/s40781-017-0127-7
  • Önem, E., Tüzün, B., & Akkoç, S. (2021). Anti-quorum sensing activ- ity in Pseudomonas aeruginos a PA01 of benzimidazolium salts: electronic, spectral and structural investigations as theoretical approach. Journal of Biomolecular Structure and Dynamics, 1-12. https://doi.org/10.1080/07391102.2021.1890222
  • Packiavathy, I. A. S. V., Agilandeswari, P., Musthafa, K. S., Pandian, S. K., & Ravi, A. V. (2012). Antibiofilm and quorum sensing inhibitory potential of Cuminum cyminum and its secondary metabolite methyl eugenol against Gram negative bacterial pathogens. Food Research Interna- tional, 45(1), 85-92. https://doi.org/10.1016/j.foodres.2011.10.022
  • Pellegrini, M. C., Alvarez, M. V., Ponce, A. G., Cugnata, N. M., De Piano, F. G., & Fuselli, S. R. (2014). Anti-quorum sensing and antimi- crobial activity of aromatic species from South America. Journal of Essential Oil Research, 26(6), 458-465. https://doi.org/10.1080/1 0412905.2014.947387
  • Raut, J. S., & Karuppayil, S. M. (2014). A status review on the me- dicinal properties of essential oils. Industrial Crops and Products, 62, 250-264. https://doi.org/10.1016/j.indcrop.2014.05.055
  • Tariq, S., Wani, S., Rasool, W., Shafi, K., Bhat, M. A., Prabhakar, A., Shalla, A.H. & Rather, M.A. (2019). A comprehensive review of the antibacterial, antifungal and antiviral potential of essential oils and their chemical constituents against drug-resistant micro- bial pathogens. Microbial Pathogenesis, 134, 103580.https://doi. org/10.1016/j.micpath.2019.103580
  • Vasavi, H. S., Arun, A. B., & Rekha, P. D. (2014). Anti-quorum sensing activity of Psidium guajava L. flavonoids against Chromobacterium violaceum and Pseudomonas aeruginosa PAO1. Microbiology and Im- munology, 58(5), 286-293. https://doi.org/10.1111/1348-0421.12150
  • Vieira, M., Bessa, L. J., Martins, M. R., Arantes, S., Teixeira, A. P., Mendes, Â., Martins da Costa, P. & Belo, A. D. (2017). Chemical composition, antibacterial, antibiofilm and synergistic proper- ties of essential oils from Eucalyptus globulus Labill. and seven Mediterranean aromatic plants. Chemistry & Biodiversity, 14(6), e1700006. https://doi.org/10.1002/cbdv.201700006
  • Vipin, C., Mujeeburahiman, M., Ashwini, P., Arun, A., & Rekha, P.
  • D. (2019). Anti‐biofilm and cytoprotective activities of quercetin against Pseudomonas aeruginosa isolates. Letters in Applied Mi- crobiology, 68(5), 464-471. https://doi.org/10.1111/lam.13129
  • Yan, M.-R., Wang, C.-H., Cruz Flores, N. J., & Su, Y.-Y. (2019). Targeting open market with strategic business innovations: a case study of growth dynamics in essential oil and aromatherapy industry. Journal of Open Innovation: Technology, Market, and Complexity, 5(1), 7. https://doi.org/10.3390/joitmc5010007
  • Yap, P. S. X., Yiap, B. C., Ping, H. C., & Lim, S. H. E. (2014). Essen- tial oils, a new horizon in combating bacterial antibiotic re- sistance. The Open Microbiology Journal, 8, 6. https://doi. org/10.2174/1874285801408010006
  • Zahin, M., Hasan, S., Aqil, F., Khan, M., Ahmad, S., Husain,F. M., & Ahmad, I. (2010). Screening of certain medicinal plants from India for their anti-quorum sensing activity. http://hdl.handle.net/123456789/10652
  • Zgoda, J., & Porter, J. (2001). A convenient microdilution method for screening natural products against bacteria and fungi. Pharmaceuti- cal Biology, 39(3), 221-225. https://doi.org/10.1076/phbi.39.3.221.5934
  • Zgurskaya, H. I., López, C. A., & Gnanakaran, S. (2015). Perme- ability barrier of Gram-negative cell envelopes and approaches to bypass it. ACS Infectious Diseases, 1(11), 512-522. https://doi. org/10.1021/acsinfecdis.5b00097
  • Zhang, D., Gan, R. Y., Zhang, J. R., Farha, A. K., Li, H. B., Zhu, F., Wang,X.H. & Corke, H. (2020). Antivirulence properties and related mechanisms of spice essential oils: A comprehensive review. Comprehensive Reviews in Food Science and Food Safety, 19(3), 1018-1055. https://doi.org/10.1111/1541-4337.12549
  • Zhang, Y., Djakpo, O., Xie, Y., Guo, Y., Yu, H., Cheng, Y., Qian, H., Shi,R. & Yao, W. (2019). Anti-quorum sensing of Galla chinensis and Coptis chinensis on bacteria. Lebensmittel-Wissenchaft und Tech- nologie, 101, 806-811. https://doi.org/10.1016/j.lwt.2018.11.090
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There are 40 citations in total.

Details

Primary Language English
Subjects Pharmacology and Pharmaceutical Sciences
Journal Section Original Article
Authors

Müjgan Özfenerci This is me 0000-0003-1720-9460

Elif Burcu Bali 0000-0002-8797-0573

Demet Erdönmez 0000-0003-3955-1734

Ufuk Koca Çalışkan 0000-0002-5216-7588

Project Number 02/2019-12
Publication Date April 28, 2022
Submission Date September 22, 2021
Published in Issue Year 2022 Volume: 52 Issue: 1

Cite

APA Özfenerci, M., Bali, E. B., Erdönmez, D., Koca Çalışkan, U. (2022). Aromatherapeutic essential oils and their pharmaceutical combinations: Tools for inhibition of quorum sensing activity and biofilm formation of human pathogens*. İstanbul Journal of Pharmacy, 52(1), 54-63. https://doi.org/10.26650/IstanbulJPharm.2022.998774
AMA Özfenerci M, Bali EB, Erdönmez D, Koca Çalışkan U. Aromatherapeutic essential oils and their pharmaceutical combinations: Tools for inhibition of quorum sensing activity and biofilm formation of human pathogens*. iujp. April 2022;52(1):54-63. doi:10.26650/IstanbulJPharm.2022.998774
Chicago Özfenerci, Müjgan, Elif Burcu Bali, Demet Erdönmez, and Ufuk Koca Çalışkan. “Aromatherapeutic Essential Oils and Their Pharmaceutical Combinations: Tools for Inhibition of Quorum Sensing Activity and Biofilm Formation of Human Pathogens*”. İstanbul Journal of Pharmacy 52, no. 1 (April 2022): 54-63. https://doi.org/10.26650/IstanbulJPharm.2022.998774.
EndNote Özfenerci M, Bali EB, Erdönmez D, Koca Çalışkan U (April 1, 2022) Aromatherapeutic essential oils and their pharmaceutical combinations: Tools for inhibition of quorum sensing activity and biofilm formation of human pathogens*. İstanbul Journal of Pharmacy 52 1 54–63.
IEEE M. Özfenerci, E. B. Bali, D. Erdönmez, and U. Koca Çalışkan, “Aromatherapeutic essential oils and their pharmaceutical combinations: Tools for inhibition of quorum sensing activity and biofilm formation of human pathogens*”, iujp, vol. 52, no. 1, pp. 54–63, 2022, doi: 10.26650/IstanbulJPharm.2022.998774.
ISNAD Özfenerci, Müjgan et al. “Aromatherapeutic Essential Oils and Their Pharmaceutical Combinations: Tools for Inhibition of Quorum Sensing Activity and Biofilm Formation of Human Pathogens*”. İstanbul Journal of Pharmacy 52/1 (April 2022), 54-63. https://doi.org/10.26650/IstanbulJPharm.2022.998774.
JAMA Özfenerci M, Bali EB, Erdönmez D, Koca Çalışkan U. Aromatherapeutic essential oils and their pharmaceutical combinations: Tools for inhibition of quorum sensing activity and biofilm formation of human pathogens*. iujp. 2022;52:54–63.
MLA Özfenerci, Müjgan et al. “Aromatherapeutic Essential Oils and Their Pharmaceutical Combinations: Tools for Inhibition of Quorum Sensing Activity and Biofilm Formation of Human Pathogens*”. İstanbul Journal of Pharmacy, vol. 52, no. 1, 2022, pp. 54-63, doi:10.26650/IstanbulJPharm.2022.998774.
Vancouver Özfenerci M, Bali EB, Erdönmez D, Koca Çalışkan U. Aromatherapeutic essential oils and their pharmaceutical combinations: Tools for inhibition of quorum sensing activity and biofilm formation of human pathogens*. iujp. 2022;52(1):54-63.