FDG-PET in diagnosis, staging and follow-up of malignant melanoma

Abstract

In this review article, the use of recent technology Flour18deoxyglucose Positron Emission Tomography (FDG-PET) in melanoma has been discussed. Studies in the medical literature regarding the use of FDG PET in early melanoma, staging of melanoma, sentinel lymph node detection, local recurrence and in transit metastasis, distant metastasis and restaging were reviewed and evaluated. Treatment evaluation with PET, recent developements in new PET radiopharmaceuticals and use of PET probe in melanoma has been quoted.

Keywords

• Melanoma,Diagnosis,Neoplasm Staging,Positron-Emission Tomography,Fluorodeoxyglucose F18

Melanomun tanı, evreleme ve takibinde FDG-PET'in değeri

Öz

Bu yazıda, son yıllarda onkolojide çeşitli tümörlerin tanı ve takibinde sıkça kullanılan Flor18-Deoksi-Glukoz Pozitron Emisyon Tomografinin (FDG-PET) melanomda kullanımı anlatıldı. Melanomun erken tanısında, hastalığın evrelenmesinde, sentinel lenf düğümünün araştırılmasında, lokal nüks ve intransit metastazlarda, uzak metastazların gösterilmesinde ve nüks durumunda yeniden evrelemede PET ile yapılmış çalışmalar ve sonuçları değerlendirildi. Tedaviye yanıt ölçümünde PET'in yeri, ayrıca yeni radyofarmasötiklerin melanomda kullanılabilirliği ve PET probla ilgili gelişmeler aktarıldı.

Anahtar Kelimeler

• Floro-deoksi-glukoz F18/tanısal kullanım, melanom/tanı, neoplazi evreleme, PET

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