Evaluation of multiple primary tumors and single tumors charecteristics: A study from hospital-based cancer registry in İzmir

Abstract

OBJECTIVES To evaluate patients with multiple primary tumors (MPTs) from the data of Izmir Cancer Registry (ICR) in Izmir Atatürk Research and Training Hospital (IAEAH) and to compare them with single tumor (ST). METHODS 572 multiple primary tumors ( MPTs) (286 patients) out of 2 0.895 tumors recorded during the period of 1993-2005 by office of ICR located in IAEAH were analyzed. Double tumors (DTs) were analyzed. Chi-square test and Independent Samples t-test were performed by SPSS 10.0. RESULTS Of patients with MPTs 53.2% had synchronous whereas 43.1% had metachronous. The mean age were 55.81±15.4 years for ST group; 61.49±13.32 for DT group (p

Keywords

• Neoplasms, Unknown Primary,İzmir,Database,Registries,Chi-Square Distribution,Records as Topic

Çok primerli ve tek primerli kanser olguları: İzmir kanser kayıt merkezi verilerinden hastane tabanlı bir inceleme

Abstract

AMAÇ Çalışmamızda İzmir Kanser İzlem Denetleme Merkezi'nin (KİDEM) İzmir Atatürk Eğitim ve Araştırma Hastanesi'ndeki (İAEAH) veri tabanınında ilk kez çoklu tümörler incelendi, tekli tümörlerle karşılaştırıldı. GEREÇ VE YÖNTEM Ekim-1993 ve Ekim-2005 arası 20.895 tümör İAEAH'de KİDEM'de kaydedildi. Çok primerli tümör 605'ti (297 hasta). Yalnızca çift primer tümörlü (ÇPT) hastalar incelendi. İstatistiksel analizlerde Chi-square test, Independent Samples t-test kullanıldı. Analizler %95'lik güven aralığında yapıldı; p < 0.05 değeri istatistiksel anlamlı kabul edildi. BULGULAR Senkron ÇPT %53.2; metakron ÇPT %43.1 idi. ÇPT’lerde kadın oranı tek primer tümörlü (TPT) olgulardan yüksekti (p < 0.008). Yaş ortalaması TPT’lerde 55.81±15.4; ÇPT’lerde 61.49±13.32 idi (p < 0.001). Ürogenital (%30.9) ve deri tümörleri (%17.1) ÇPT’de anlamlı olarak daha yüksekti. İki grupta en sık adenokarsinom gözlendi. ÇPT’lerde iki tümör arası süre (metakronlarda) 44.4±30.82 (38.99-49.77) aydı. SONUÇ ÇPT’lerde ürogenital ve cilt tümörlerinin sıklığı “alan kanserleşmesi”, ortak klonal köken, tarama-izlem, uzayan sağkalım konusunda ipuçları taşımaktadır. Uluslararası kayıt sistemini kullanan değişik toplumlarda insidans, ayrıca nedensel çalışmaların artışıyla aydınlatılma ihtiyacındadır.

Keywords

• Tümör, çoklu primer, tekli primer, kanser kayıt

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