Malignant melanomas in anorectal region: Report of four cases

Abstract

After the skin and eyes, the third most frequently encountered location of melanoma is the anorectal region. The aim of this study was to review our experience about anorectal malignant melanoma and share the results with other colleagues. The medical records of the patients treated for malignant melanoma in our clinic between 1998 and 2008 were retrospectively reviewed. Three of the four patients were male. The mean age of the patients was 54.75 years (45-64). All patients were admitted with rectal bleeding. Three of the patients died due to disseminated disease in the first two years. Early detection is crucial in oncological surgery in order to achieve a curative resection. Despite all of the therapeutic efforts, primary anorectal malignant melanoma is a rare and aggressive neoplasm associated with an extremely poor prognosis, usually because of a delay in the diagnosis period.

Keywords

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Anorektal bölge yerleşimli malign melanomlar: Dört olgunun sunumu

Öz

Melanomun deri ve gözden sonra en sık rastlandığı üçüncü yer anorektal bölgedir. Bu çalışmanın amacı anorektal malign melanom ile ilgili deneyimlerimizi gözden geçirmek ve meslektaşlarımızla paylaşmaktır. Kliniğimizde 1998 ve 2008 yılları arasında tedavi edilen dört malign melanomlu hastanın verileri geriye dönük olarak incelendi. Dört hastanın üçü erkekti. Ortalama yaş 54,75 (dağılım 45-64) idi. Tüm hastalarda esas yakınma rektal kanamaydı. Dört hastanın üçü ilk iki yıl içinde dissemine hastalık sebebi ile kaybedildi. Onkolojik cerrahide küratif rezeksiyon yapabilmek için erken teşhis şarttır. Primer anorektal malign melanom genellikle tanıdaki gecikmeler nedeniyle tüm tedavi çabalarına karşın oldukça kötü prognoza sahip saldırgan ve nadir bir tümördür.

Anahtar Kelimeler

• Abdominoperineal rezeksiyon, kanser, malign melanom

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