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The experience of hyperbaric oxygen therapy in soft tissue radionecrosis: a case report

Year 2006, Volume: 21 Issue: 1, 47 - 51, 01.02.2006

Abstract

Radiation's late effects may lead to complex and potentially devastating complications in normal tissue. In many cases, resulting radionecrotic lesions seriously impair form and function which may be life-threatening and more devastating than primary malignant disease. Hyperbaric oxygen therapy is being used for treatment of radionecrosis for the last twenty years and is included in indication list of two important scientific committees, Undersea and Hyperbaric Medical Society (UHMS) and European Commitee for Hyperbaric Medicine (ECHM). In this report, we present an upper outside quadrant of the breastsoft tissue radionecrosis case which treated with HBO. The efficacy of hyperbaric oxygenation was followed by LENT/SOMA scoring. After 40 sessions of daily 90 minutes of HBO therapy at 2.0 ATA (athmosphere absolute) in a monoplace pressure chamber, the LENT/SOMA scoring which was 23/1.642 (LENT score 1/2) on admission found to be 12/0.857 by the end of the therapy and 4/0.285 on sixth month control examinations.

References

  • 1. Burman C, Kutcher GJ, Emami B, Goitein M. Fitting of normal tissue tolerance data to an analytic function. Int J Radiat Oncol Biol Phys 1991;21(1):123-35.
  • 2. Fowler JF. Fractionation and therapeutic gain. In: Steel GE, Adams GE, Peckham MT, editors. Biological basis of radiotherapy. Amsterdam: Elsevier Science; 1983. p. 181-94.
  • 3. Pasquier D, Hoelscher T, Schmutz J, Dische S, Mathieu D, Baumann M, et al. Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: a literature review. Radiother Oncol 2004;72(1):1-13.
  • 4. Baumann M. Impact of endogeneous and exogeneous factors on radiation sequelae In: Dunst J, Sauer R, editors. Late sequelae in oncology. Berlin: Springer Verlag; 1995. p. 3-12.
  • 5. Baumann M, Bentzen SM. Clinical manifestation of normal tissue damage. In: Steel GG, editor. Basic clinical radiobiology. 3rd ed. London: Arnold; 2002. p. 105-19.
  • 6. Marx RE. Radiation injury to tissue. In: Kindwall EP, Whelan HT, editors. Hyperbaric medicine practice. 2nd ed. Flagstaff, AZ: Best Publishing; 2002. p. 665-724. 7. Feldmeier JJ. The hyperbaric oxygen therapy committee report UHMS. In: Feldmeier JJ, editor. Hyperbaric oxygen 2003. Indications and results. Kensington, Maryland: 2003. p. 87-100.
  • 8. Bevers RF, Bakker DJ, Kurth KH. Hyperbaric oxygen treatment for haemorrhagic radiation cystitis. Lancet 1995;346(8978):803-5.
  • 9. Woo TC, Joseph D, Oxer H. Hyperbaric oxygen treatment for radiation proctitis. Int J Radiat Oncol Biol Phys 1997;38(3):619-22.
  • 10. Williams JA Jr, Clarke D, Dennis WA, Dennis EJ 3rd, Smith ST. The treatment of pelvic soft tissue radiation necrosis with hyperbaric oxygen. Am J Obstet Gynecol 1992;167(2):412-5.
  • 11. Feldmeier JJ, Heimbach RD, Davolt DA, Brakora MJ. Hyperbaric oxygen as an adjunctive treatment for severe laryngeal necrosis: a report of nine consecutive cases. Undersea Hyperb Med 1993;20(4):329-35.
  • 12. Unpublished Report (Long Version): Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues. 5th European Consensus Conference on Hyperbaric Medicine; October 19-20, 2001; Lisbon, Portugal.
  • 13. Feldmeier J, Carl U, Hartmann K, Sminia P. Hyperbaric oxygen: does it promote growth or recurrence of malignancy? Undersea Hyperb Med 2003;30(1):1-18.
  • 14. Hymes SR, Strom EA, Fife C. Radiation dermatitis: clinical presentation, pathophysiology, and treatment 2006. J Am Acad Dermatol 2006;54(1):28-46.
  • 15. Pavy JJ, Denekamp J, Letschert J, Littbrand B, Mornex F, Bernier J, et al. EORTC Late Effects Working Group. Late Effects toxicity scoring: the SOMA scale. Int J Radiat Oncol Biol Phys 1995;31(5):1043-7.

Yumuşak doku radyonekrozunda hiperbarik oksijen tedavisi deneyimi: Olgu sunumu

Year 2006, Volume: 21 Issue: 1, 47 - 51, 01.02.2006

Abstract

Geç dönem radyasyon hasarları organ ve dokularda ciddi yapısal ve fonksiyonel bozukluklara yol açabilir. Yirmi yılı aşkın süredir radyonekrozların tedavisinde kullanılan “Hiperbarik Oksijen Tedavisi”, Undersea Hyperbaric Medical Society (UHMS) ve European Committee for Hyperbaric Medicine (ECHM) gibi Hiperbarik Tıp alanındaki çok önemli iki bilimsel kuruluşun endikasyonlar listesinde yer almaktadır. Bu yazıda nadir bir klinik prezentasyon olarak meme üst dış kadran yerleşimli enfekte yumuşak doku radyonekrozu olgusunda tek başına hiperbarik oksijen tedavisi ile elde edilen sonuçlar sunuldu. Tedavinin etkinliği LENT/SOMA cetveli ile takip edildi. Başlangıçta 23/1.642 olan LENT/SOMA skoru (LENT skoru 1/2), tek kişilik basınç odasında 2 ATA (atmosfer absolut) basınçta, 90 dakika süreyle uygulanan toplam 40 seanslık tedavinin ardından 12/0.857 ve altı ay sonunda 4/0.285 olarak belirlendi.

References

  • 1. Burman C, Kutcher GJ, Emami B, Goitein M. Fitting of normal tissue tolerance data to an analytic function. Int J Radiat Oncol Biol Phys 1991;21(1):123-35.
  • 2. Fowler JF. Fractionation and therapeutic gain. In: Steel GE, Adams GE, Peckham MT, editors. Biological basis of radiotherapy. Amsterdam: Elsevier Science; 1983. p. 181-94.
  • 3. Pasquier D, Hoelscher T, Schmutz J, Dische S, Mathieu D, Baumann M, et al. Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: a literature review. Radiother Oncol 2004;72(1):1-13.
  • 4. Baumann M. Impact of endogeneous and exogeneous factors on radiation sequelae In: Dunst J, Sauer R, editors. Late sequelae in oncology. Berlin: Springer Verlag; 1995. p. 3-12.
  • 5. Baumann M, Bentzen SM. Clinical manifestation of normal tissue damage. In: Steel GG, editor. Basic clinical radiobiology. 3rd ed. London: Arnold; 2002. p. 105-19.
  • 6. Marx RE. Radiation injury to tissue. In: Kindwall EP, Whelan HT, editors. Hyperbaric medicine practice. 2nd ed. Flagstaff, AZ: Best Publishing; 2002. p. 665-724. 7. Feldmeier JJ. The hyperbaric oxygen therapy committee report UHMS. In: Feldmeier JJ, editor. Hyperbaric oxygen 2003. Indications and results. Kensington, Maryland: 2003. p. 87-100.
  • 8. Bevers RF, Bakker DJ, Kurth KH. Hyperbaric oxygen treatment for haemorrhagic radiation cystitis. Lancet 1995;346(8978):803-5.
  • 9. Woo TC, Joseph D, Oxer H. Hyperbaric oxygen treatment for radiation proctitis. Int J Radiat Oncol Biol Phys 1997;38(3):619-22.
  • 10. Williams JA Jr, Clarke D, Dennis WA, Dennis EJ 3rd, Smith ST. The treatment of pelvic soft tissue radiation necrosis with hyperbaric oxygen. Am J Obstet Gynecol 1992;167(2):412-5.
  • 11. Feldmeier JJ, Heimbach RD, Davolt DA, Brakora MJ. Hyperbaric oxygen as an adjunctive treatment for severe laryngeal necrosis: a report of nine consecutive cases. Undersea Hyperb Med 1993;20(4):329-35.
  • 12. Unpublished Report (Long Version): Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues. 5th European Consensus Conference on Hyperbaric Medicine; October 19-20, 2001; Lisbon, Portugal.
  • 13. Feldmeier J, Carl U, Hartmann K, Sminia P. Hyperbaric oxygen: does it promote growth or recurrence of malignancy? Undersea Hyperb Med 2003;30(1):1-18.
  • 14. Hymes SR, Strom EA, Fife C. Radiation dermatitis: clinical presentation, pathophysiology, and treatment 2006. J Am Acad Dermatol 2006;54(1):28-46.
  • 15. Pavy JJ, Denekamp J, Letschert J, Littbrand B, Mornex F, Bernier J, et al. EORTC Late Effects Working Group. Late Effects toxicity scoring: the SOMA scale. Int J Radiat Oncol Biol Phys 1995;31(5):1043-7.
There are 14 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Şefika Körpınar

Akın Savaş Toklu This is me

Didem Karaçetin This is me

Publication Date February 1, 2006
Published in Issue Year 2006 Volume: 21 Issue: 1

Cite

APA Körpınar, Ş., Toklu, A. S., & Karaçetin, D. (2006). Yumuşak doku radyonekrozunda hiperbarik oksijen tedavisi deneyimi: Olgu sunumu. Türk Onkoloji Dergisi, 21(1), 47-51.
AMA Körpınar Ş, Toklu AS, Karaçetin D. Yumuşak doku radyonekrozunda hiperbarik oksijen tedavisi deneyimi: Olgu sunumu. Türk Onkoloji Dergisi. February 2006;21(1):47-51.
Chicago Körpınar, Şefika, Akın Savaş Toklu, and Didem Karaçetin. “Yumuşak Doku Radyonekrozunda Hiperbarik Oksijen Tedavisi Deneyimi: Olgu Sunumu”. Türk Onkoloji Dergisi 21, no. 1 (February 2006): 47-51.
EndNote Körpınar Ş, Toklu AS, Karaçetin D (February 1, 2006) Yumuşak doku radyonekrozunda hiperbarik oksijen tedavisi deneyimi: Olgu sunumu. Türk Onkoloji Dergisi 21 1 47–51.
IEEE Ş. Körpınar, A. S. Toklu, and D. Karaçetin, “Yumuşak doku radyonekrozunda hiperbarik oksijen tedavisi deneyimi: Olgu sunumu”, Türk Onkoloji Dergisi, vol. 21, no. 1, pp. 47–51, 2006.
ISNAD Körpınar, Şefika et al. “Yumuşak Doku Radyonekrozunda Hiperbarik Oksijen Tedavisi Deneyimi: Olgu Sunumu”. Türk Onkoloji Dergisi 21/1 (February 2006), 47-51.
JAMA Körpınar Ş, Toklu AS, Karaçetin D. Yumuşak doku radyonekrozunda hiperbarik oksijen tedavisi deneyimi: Olgu sunumu. Türk Onkoloji Dergisi. 2006;21:47–51.
MLA Körpınar, Şefika et al. “Yumuşak Doku Radyonekrozunda Hiperbarik Oksijen Tedavisi Deneyimi: Olgu Sunumu”. Türk Onkoloji Dergisi, vol. 21, no. 1, 2006, pp. 47-51.
Vancouver Körpınar Ş, Toklu AS, Karaçetin D. Yumuşak doku radyonekrozunda hiperbarik oksijen tedavisi deneyimi: Olgu sunumu. Türk Onkoloji Dergisi. 2006;21(1):47-51.