Primeri bilinmeyen küçük hücreli karsinom tanılı hastada iris ve koroid metastazı: Olgu sunumu

Ahmet Karadeniz; Serap Başkaya; Arzu Ergen

Primeri bilinmeyen küçük hücreli karsinom tanılı hastada iris ve koroid metastazı: Olgu sunumu

Year 2006, Volume: 21 Issue: 2, 98 - 101, 01.03.2006

Ahmet Karadeniz Serap Başkaya Arzu Ergen

Abstract

Beyinde multipl metastaz ön tanısı ile acil radyoterapi için İstanbul Üniversitesi Onkoloji Enstütüsü'ne sevk edilen hastanın yapılan tetkiklerinde multipl lenfadenopatiler (LAP) saptandı. İnguinal LAP'dan biri eksizyonla çıkarıldı. Yapılan histopatoloji incelemesinde nöroendokrin differansiasyonlu küçük hücreli karsinom tanısı konuldu. Kraniyal radyoterapi sonrası sistemik kemoterapi uygulanan hasta, tedaviden 13 ay sonra sağ göz iris ve koroid bölge metastazı ile yeniden kliniğimize başvurdu. Sağ orbitaya palyatif radyoterapi uygulanan hastada radyoterapiye hızlı bir yanıt alınarak başarılı palyasyon sağlandı.

Keywords

Koroid neoplazi/ikincil, göz hastalığı/etyoloji, iris neoplazisi/patoloji/ikincil, uveal neoplazi/komplikasyo

References

1) Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE. Survey of 520 eyes with uveal metastases. Ophthalmology 1997;104(8):1265-76
2) Shields JA, Shields CL. Intraocular tumors; a text and atlas. Philadelphia: W.B. Saunders; 1992. p. 207-48
3) Shields JA, Shields CL, Kiratli H, de Potter P. Metastatic tumors to the iris in 40 patients. Am J Ophthalmol 1995;119(4):422-30
4) Mouriaux F, Labalette P, Prevost B, Constantinides G. Iris metastases. Apropos of 4 cases. [Article in French] J Fr Ophtalmol 1997;20(1):37-41. [Abstract] 5) Neitzke R, Spraul CW, Lang GE, Lang GK. Iris metastases in breast carcinoma. [Article in German] Ophthalmologe 2001;98(11):1097-100. [Abstract] 6) Sen HN, Chan CC, Nussenblatt RB, Buggage RR. Occult primary carcinoma metastatic to the iris. Acta Ophthalmol Scand 2004;82(6):746-7
7) Demirci H, Shields CL, Chao AN, Shields JA. Uveal metastasis from breast cancer in 264 patients. Am J Ophthalmol 2003;136(2):264-71
8) Gutierrez Sanchez E, Alonso Alonso I. Metastasis to the iris: a casual finding. [Article in Spanish] Arch Soc Esp Oftalmol 2000;75(10):689-91. [Abstract] 9) Mayama C, Ohashi M, Tomidokoro A, Kojima T. Bilateral iris metastases from prostate cancer. Jpn J Ophthalmol 2003;47(1):69-71
10) Barishak YR, Baruh E, Lazar M. Metastatic tumor of the iris: case report. Ann Ophthalmol 1978;10(9):1191-3
11) Freeman TR, Friedman AH. Metastatic carcinoma of the iris. Am J Ophthalmol 1975;80(5):947-52
12) Wyzinski P, Rootman J, Wood W. Simultaneous bilateral iris metastases from renal cell carcinoma. Am J Ophthalmol 1981;92(2):206-9
13) Ware GT, Haik BG, Morris WR. Renal cell carcinoma with involvement of iris and conjunctiva. Am J Ophthalmol 1999;127(4):460-1
14) Capeans C, Santos L, Sanchez-Salorio M, Forteza J. Iris metastasis from endometrial carcinoma. Am J Ophthalmol 1998;125(5):729-30
15) Duke JR, Walsh FB. Metastatic carcinoma to the retina. Am J Ophthalmol 1959;47(1 Part 1):44-8
16) De Potter P, Shields CL, Shields JA, Tardio DJ. Uveal metastasis from prostate carcinoma. Cancer 1993;71(9):2791-6
17) Rodrigues M, Shields JA. Iris metastasis from a bronchial carcinoid tumor. Arch Ophthalmol 1978;96(1):77-83
18) Sach J, Krepelkova J, Kuchynka P. Haemangiosarcoma of the breast, metastatic to the ciliary body and iris. Br J Ophthalmol 1998;82(6):709-11
19) Martin M, Zierhut D, Piroth M, Gutwein S, Debus J, Dithmar S. Solitary iris metastasis from breast cancer. Effective local therapy with electron beam irradiation. [Article in German] Ophthalmologe 2006;103(1):48- 51. [Abstract] 20) Songür N, Soysal HG, Kıratlı H. Küçük hücreli dışı akciğer kanserinde nadir bir tutulum; iris metastazı. Toraks Dergisi 2004;5(3):208-10
21) Ichiki Y, Morita M, Yano K, Sugio K, Yasumoto K, Hirose N. Iris metastasis of esophageal cancer. Ann Thorac Surg 2005;79(5):1782-4

Iris and choroid metastases from a patient with small cell carcinoma of unknown primary: a case report

Year 2006, Volume: 21 Issue: 2, 98 - 101, 01.03.2006

Ahmet Karadeniz Serap Başkaya Arzu Ergen

Abstract

A patient with multiple brain metastases was referred to University of İstanbul Institute of Oncology for emergency treatment of multiple brain metastases. Excisional biopsy of an inguinal lymphadenopathy showed small cell carcinoma with neuroendocrin differentiation. The patient was then received cranial irradiation and chemotherapy. Thirteen months later after initial treatment, he developed metastases of iris and choroid region of the right eye and was referred to the same clinic. After application of palliative radiotherapy to the right orbit, metastases have been regressed quickly and palliation has been obtained successfully.

Keywords

Choroid Neoplasms, Middle Aged, Male, Carcinoma, Small Cell, Magnetic Resonance Imaging, Radiotherapy, Uveal Neoplasms, Neoplasms, Unknown Primary

References

1) Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE. Survey of 520 eyes with uveal metastases. Ophthalmology 1997;104(8):1265-76
2) Shields JA, Shields CL. Intraocular tumors; a text and atlas. Philadelphia: W.B. Saunders; 1992. p. 207-48
3) Shields JA, Shields CL, Kiratli H, de Potter P. Metastatic tumors to the iris in 40 patients. Am J Ophthalmol 1995;119(4):422-30
4) Mouriaux F, Labalette P, Prevost B, Constantinides G. Iris metastases. Apropos of 4 cases. [Article in French] J Fr Ophtalmol 1997;20(1):37-41. [Abstract] 5) Neitzke R, Spraul CW, Lang GE, Lang GK. Iris metastases in breast carcinoma. [Article in German] Ophthalmologe 2001;98(11):1097-100. [Abstract] 6) Sen HN, Chan CC, Nussenblatt RB, Buggage RR. Occult primary carcinoma metastatic to the iris. Acta Ophthalmol Scand 2004;82(6):746-7
7) Demirci H, Shields CL, Chao AN, Shields JA. Uveal metastasis from breast cancer in 264 patients. Am J Ophthalmol 2003;136(2):264-71
8) Gutierrez Sanchez E, Alonso Alonso I. Metastasis to the iris: a casual finding. [Article in Spanish] Arch Soc Esp Oftalmol 2000;75(10):689-91. [Abstract] 9) Mayama C, Ohashi M, Tomidokoro A, Kojima T. Bilateral iris metastases from prostate cancer. Jpn J Ophthalmol 2003;47(1):69-71
10) Barishak YR, Baruh E, Lazar M. Metastatic tumor of the iris: case report. Ann Ophthalmol 1978;10(9):1191-3
11) Freeman TR, Friedman AH. Metastatic carcinoma of the iris. Am J Ophthalmol 1975;80(5):947-52
12) Wyzinski P, Rootman J, Wood W. Simultaneous bilateral iris metastases from renal cell carcinoma. Am J Ophthalmol 1981;92(2):206-9
13) Ware GT, Haik BG, Morris WR. Renal cell carcinoma with involvement of iris and conjunctiva. Am J Ophthalmol 1999;127(4):460-1
14) Capeans C, Santos L, Sanchez-Salorio M, Forteza J. Iris metastasis from endometrial carcinoma. Am J Ophthalmol 1998;125(5):729-30
15) Duke JR, Walsh FB. Metastatic carcinoma to the retina. Am J Ophthalmol 1959;47(1 Part 1):44-8
16) De Potter P, Shields CL, Shields JA, Tardio DJ. Uveal metastasis from prostate carcinoma. Cancer 1993;71(9):2791-6
17) Rodrigues M, Shields JA. Iris metastasis from a bronchial carcinoid tumor. Arch Ophthalmol 1978;96(1):77-83
18) Sach J, Krepelkova J, Kuchynka P. Haemangiosarcoma of the breast, metastatic to the ciliary body and iris. Br J Ophthalmol 1998;82(6):709-11
19) Martin M, Zierhut D, Piroth M, Gutwein S, Debus J, Dithmar S. Solitary iris metastasis from breast cancer. Effective local therapy with electron beam irradiation. [Article in German] Ophthalmologe 2006;103(1):48- 51. [Abstract] 20) Songür N, Soysal HG, Kıratlı H. Küçük hücreli dışı akciğer kanserinde nadir bir tutulum; iris metastazı. Toraks Dergisi 2004;5(3):208-10
21) Ichiki Y, Morita M, Yano K, Sugio K, Yasumoto K, Hirose N. Iris metastasis of esophageal cancer. Ann Thorac Surg 2005;79(5):1782-4

There are 17 citations in total.

Details

Primary Language	Turkish
Journal Section	Articles
Authors	Ahmet Karadeniz This is me Serap Başkaya This is me Arzu Ergen This is me
Publication Date	March 1, 2006
Published in Issue	Year 2006 Volume: 21 Issue: 2

Cite

APA	Karadeniz, A., Başkaya, S., & Ergen, A. (2006). Primeri bilinmeyen küçük hücreli karsinom tanılı hastada iris ve koroid metastazı: Olgu sunumu. Türk Onkoloji Dergisi, 21(2), 98-101.
AMA	Karadeniz A, Başkaya S, Ergen A. Primeri bilinmeyen küçük hücreli karsinom tanılı hastada iris ve koroid metastazı: Olgu sunumu. Türk Onkoloji Dergisi. March 2006;21(2):98-101.
Chicago	Karadeniz, Ahmet, Serap Başkaya, and Arzu Ergen. “Primeri Bilinmeyen küçük hücreli Karsinom tanılı Hastada Iris Ve Koroid metastazı: Olgu Sunumu”. Türk Onkoloji Dergisi 21, no. 2 (March 2006): 98-101.
EndNote	Karadeniz A, Başkaya S, Ergen A (March 1, 2006) Primeri bilinmeyen küçük hücreli karsinom tanılı hastada iris ve koroid metastazı: Olgu sunumu. Türk Onkoloji Dergisi 21 2 98–101.
IEEE	A. Karadeniz, S. Başkaya, and A. Ergen, “Primeri bilinmeyen küçük hücreli karsinom tanılı hastada iris ve koroid metastazı: Olgu sunumu”, Türk Onkoloji Dergisi, vol. 21, no. 2, pp. 98–101, 2006.
ISNAD	Karadeniz, Ahmet et al. “Primeri Bilinmeyen küçük hücreli Karsinom tanılı Hastada Iris Ve Koroid metastazı: Olgu Sunumu”. Türk Onkoloji Dergisi 21/2 (March 2006), 98-101.
JAMA	Karadeniz A, Başkaya S, Ergen A. Primeri bilinmeyen küçük hücreli karsinom tanılı hastada iris ve koroid metastazı: Olgu sunumu. Türk Onkoloji Dergisi. 2006;21:98–101.
MLA	Karadeniz, Ahmet et al. “Primeri Bilinmeyen küçük hücreli Karsinom tanılı Hastada Iris Ve Koroid metastazı: Olgu Sunumu”. Türk Onkoloji Dergisi, vol. 21, no. 2, 2006, pp. 98-101.
Vancouver	Karadeniz A, Başkaya S, Ergen A. Primeri bilinmeyen küçük hücreli karsinom tanılı hastada iris ve koroid metastazı: Olgu sunumu. Türk Onkoloji Dergisi. 2006;21(2):98-101.