Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor
Abstract
The transmissible venereal
tumor (TVT) is a contagious and sexually transmissible neoplasia of unknown origin.
In natural conditions the tumor mainly affects the external genitalia of both
male and female dogs. A 6- year old male German shepherd dog, weighing 16 kg
was presented for evaluation of a mass on the nasal cavity which the owner had
noticed 2 months ago. Clinical examination revealed multiple nodular ulcerated
lesions of varying sizes from 1 to 3 cm in diameter over the nasal cavity. The
tumor mass had a firm consistency, was hyperemic and ulcerated.
Histopathological examination showed uniform-sized dense cells arranged in
solid sheets and clusters interlaced by a little connective-tissue stroma. The
cells were round and ovoid, with a moderate amount of cytoplasm that was either
clear or finely granular and had a large nuclear/ cytoplasmic ratio. On the
basis of the clinicopathological findings, this mass was diagnosed as a
transmissible venereal tumor.
Keywords
References
- Behera, S.K., Kurade, N.P., Monsang, S.W., Das, D.P., Mishra, K.K., Mohanta, R.K., 2012. Clinicopathological findings in a case of canine cutaneous metastatic transmissible venereal tumor. Veterinarski Arhiv 82 (4), 401-410.
- Cohen, D., 1985. The canine transmissible venereal tumor: a unique result of tumor progression. Advances in Cancer Research 43, 75-112.
- Coskan, A.S., Alcigir, M.E., Vural, S.A., 2011. Pathomorphological and immunohistochemical findings in a case of extragenital canine transmissible veneral tumor. Bulgarian Journal of Veterinary Medicine 14, 252-256.
- Das, U., Das, A.K., 2000. Review of canine transmissible venereal tumor sarcoma. Veterinary research communications 24, 545-556.
- Ferreira, A.J., Jaggy, A., Varejao, A.P., Ferreira, M.L., Correia, J.M., Mulas, J.M., Almeida, O., Oliveira, P., Prada J. 2000. Brain and ocular metastases from a transmissible venereal tumor in a dog. Journal of Small Animal Practice 41, 165-168.
- Goldschmidt, M.H., Hendrick, M.J., 2002. Tumors in domestic animals. In: Meuten, D.J. (Ed.), Tumors of the skin and soft tissues. 4th ed., Iowa State Press, Ames, Iowa, USA, pp. 45-48.
- Mukaratirwa, S., Gruys, E., 2004. Canine transmissible venereal tumour: cytogenetic origin, immunophenotype, and immunobiology. A review. Veterinary Quarterly 25, 101–111.
- Papazoglou, L.G., Koutinas, A.F., Plevraki, A.G., Tontis, D., 2001. Primary intranasal Transmissible Venereal Tumour in the dog: a retrospective study of six spontaneous cases. J Vet Med A Physiol Pathol Clin Med 48, 391-400.
Details
Primary Language
Turkish
Subjects
Health Care Administration
Journal Section
Case Report
Authors
Ghasem Farjanıkısh
This is me
Department of Pathobiology, Faculty of Veterinary Medicine, Lorestan University, Khorram Abad, Iran
Iran
Publication Date
January 1, 2017
Submission Date
December 19, 2015
Acceptance Date
April 5, 2016
Published in Issue
Year 2017 Volume: 43 Number: 1