Kanatlı Hayvanların Yeni Bir Patojeni: Helicobacter pullorum

Year 2012, Volume: 38 Issue: 2, 197 - 205, 15.11.2012

Beren Başaran Kahraman , Seyyal Ak

Abstract

ÖZET

Son yıllarda tanınan Enterohepatik Helicobacter cinslerine dâhil olan H. pullorum' un tavukçuluk sektörünü etkileyebilecek önemli bir patojen olduğu düşünülmektedir. Ayrıca etkenin gıda kaynaklı zoonoz olma ihtimalinin yüksek olması ve insanlarda gastroenterit, karaciğer ve safra kesesi hastalıklarıyla ilişkisi olduğunun düşünülmesi, şiddetli diare ile sonuçlanan vakalardan izole edilmesi etkenin önemini daha da arttırmaktadır. Bu derlemede H. pullorum'un etiyolojisi, epizootiyolojisi, tanısı ve önemi tartışılmıştır.

Anahtar Kelimeler: Helicobacter spp., tavuk, insan, bağırsak

 

ABSTRACT

A NEW PATHOGEN IN POULTRY: HELICOBACTER PULLORUM

Enterohepatic Helicobacter species, including H. pullorum, are increasingly recognized as microbial pathogens for the poultry industry. Also, H. pullorum has been high probability of being zoonotic food-borne pathogen and with relations of gastroenteritis, the liver and gall bladder disease in humans, isolation of the agent which cases with severe diarrhea increased the value of the agent. In this review, H. pullorum's etiology, epizootiology, diagnosis and significance are discussed.

Key Words: Helicobacter spp., chicken, human, intestine

Keywords

Helicobacter spp., tavuk, insan, bağırsak

References

• Abu Al-Soud, W., Stenramc, U., Ljungh, A., Tranberg, K.G., Nilsson, H.O., Wadstroma, T., 2008. DNA of Helicobacter spp. and common gut bacteria in primary liver carcinoma. Digestive and Liver Disease 40, 126-131.
• Ananieva, O., Nilsson, I . , Vorobjova, T., Uibo, R., Wadström, T., 2002. Immune responses to bile- tolerant Helicobacter species in patients with chronic liver diseases, a randomized population group, and healthy blood donors. Clinical and Diagnostic Laboratory Immunology 9, 1160ı 1164.
• Andersen, L.P., 2001. New Helicobacter species in humans. Digestive Diseases 19, 112-115.
• Atabay, H.I., Corry, J . E . L . , On, S.L.W., 1998. Identification of unusual Campylobacter-like isolates from poultry products as Helicobacter pullorum. Journal of Applied Microbiology 84, 1017-1024.
• Başaran Kahraman, B., 2010. Marmara Bölgesinde tavuklarda Helicobacter pullorum'un varlığının araştırılması. Doktora Tezi, İstanbul Üniversitesi Sağlık Bilimleri Enstitüsü, İstanbul.
• Burnens, A.P., Stanley, J . , Morgenstern, R., Nicolet, J . , 1994. Gastroenteritis associated with Helicobacter pullorum. Lancet 344, 1569-1570.
• Burnens, A.P., Stanley, J . , Nicolet, J , 1996. Possible Association of Helicobacter pullorum with Lesions of Vibrionic Hepatitis in Poultry. In: Newell, D.G., Ketley, J.M., Feldman, R.A. (Eds.), Campylobacters, Helicobacters and Related Organism. New York Plenum Press, pp. 291-293.
• Ceelen, L . M . , Decostere, A., Verschraegen, G., Ducatelle, R., Haesebrouck, F . , 2005a. Prevalence of Helicobacter pullorum among Patients with gastrointestinal disease and clinically healthy persons. Journal of Clinical Microbiology 43 (6), 2984-2986.
• Ceelen, L . M . , Decoster, A., Devriese, L . A . , Ducatelle, R., Haesebrouck, F., 2005b. In vitro susceptibility of Helicobacter pullorum isolates to different antimicrobial agents. Microbial Drug Resistance 11, 122-125.
• Ceelen, L.M., Decostere, A., Van den Bulck, K., Stephen, L.W., Margo, B., Ducatelle, R., Haesebrouck, F., 2006a. Helicobacter pullorum in Chickens, Belgium. Emerging Infectious Diseases 12, 263-267.
• Ceelen, L.M., Decostere, A., Van den Bulck, K., On, S.L.W., Baele, M., Ducatelle, R., Haesebrouck, F., 2006b. Occurence of Helicobacter pullorum in broiler chickens and comparison of isolates using amplified fragment ength polymorphism profiling. Emerging Infectious Diseases 12, 263ı
• Ceelen, L . , Decostere, A., Martel, A., Pasmans, F . , Haesebrouck, F . , 2006c. First report of Helicobacter pullorum in the faece of a diarrhoeic psittacine bird (Psephotus haematogaster). The Veterinary Record 159, 389-390.
• Ceelen, L . M . , Haesebrouck, F . , Favoreel, H., Ducatelle, R., Decoster, A., 2006d. The cytolethal distending toxin among Helicobacter pullorum isolates from human and pultry origin. Veterinary Microbiology 113, 45-53.
• Ceelen, L.M., Decostere, A., Chiers, K . , Ducatelle, R., Maes, D., Haesebrouck, F . , 2007. Pathogenesis of Helicobacter pullorum infections in broilers. International Journal of Food Microbiology 116, 207-213.
• Corry, J . E . , Atabay, H.I., 1997. Comparison of the productivity of cefoperazone amphotericin teicoplanin (CAT) agar and modified charcoal cefoperazone deoxycholate (mCCD) agar for various strains of Campylobacter, Arcobacter and Helicobacter pullorum. International Journal of Food Microbiology 38, 201-209.
• Dewhirst, F . E . , Shen, Z., Scimeca, M.S., Stokes, L . N., Boumenna, T., Chen, T., Paster, B.J., Fox, J.G., 2005. Discordant 16S and 23S rRNA Gene Phylogenies for the Genus Helicobacter: Implications for Phylogenetic Inference and Systematics. Journal of Bacterilogy 187 (17), 6106-6118.
• Fox, J.G., Lee, A., 1997. The role of Helicobacter species in nely recognized gastrointestinal tract diseases of animals. Laboratory Animal Science 47, 222-225.
• Fox, J.G., Chien, C.C., Dewhirst, F . E . , Paster, B.J., Shen, Z., Melito, P.L., Woodward, D.L., Rodgers, F.G., 2000. Helicobacter canadensis sp. nov. isolated from humans with diarrhea as an example of an emerging pathogen. Journal of Clinical Microbiology 38, 2546-2549.
• Fox, J.G., 2002. The non-H. pylori helicobacters. Their expanding role in gastrointestinal and systemic disases. Gut 50, 273-283.
• Frisk, A., Lebens, M., Johansson, C . , Ahmed, H., Svensson, L . , Ahlman, K., Lagergärd, T., 2001. The role of different protein components from the Haemophilus ducreyi cytolethal distending toxin in the generation of cell toxicity. Microbial Pathogenesis 30, 313-324.
• Gibson, J.R., Ferrus, M.A., Woodward, D., Xerry, J . , Owen, R . J . , 1999. Genetic diversity in Helicobacter pullorum from human and poultry sources identified by an amplified fragment length polymorphism technique and pulsed-field gel electrophoresis. Journal of Applied Microbiology 87, 602-610.
• Hynes, S.O., Ferris, J.A., Szponar, B., Wadstroem, T., Fox, J . G . , O'Rourke, J . , Larsson, L . , Yaquian, E . , Ljungh, A., Clyne, M., Andersen, L.P., Moran, A.P., 2004. Comparative chemical and biological characterization of the lipopolysaccharides of gastric and enterohepatic helicobacters. Helicobacter 9, 313-323.
• Johnson, W.M., Lior, H., 1987. Response of Chinese ovary hamster cells to a cytolethal distending toxin (CDT) of Escherichia coli and possible misinterpretation as heat-labile (LT) enterotoxin. FEMS Microbiology Letter 43, 19-23.
• Lara-Tejero, M., Galan, J . E . , 2001. CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infection and Immunity 69, 4358-4365.
• Lönngren, V., Nilsson, I., Verbaan, H., Wadström, T., Ljungh, A., 2009. High levels of serum antibodies to cell surface proteins of Helicobacter pullorum and Helicobacter pylori in hepatitis C virus-infected patients. Scandinavian Journal of Gastroenterology 44, 505-506.
• Manfreda, G., Rossi, M., Sanguinetti, V., Gavioli, R., Lozito, P., De Cesare, A., Zanoni, R.G., 2006. Prevalence of Helicobacter pullorum in broiler chickens reared in intensive and extensive farms. World's Poultry Science Journal 62, 551ı 552.
• Martel, C., Plummer, M., Parsonnet, J . , van Doorn L . J . , Franceschi, S., 2009. Helicobacter species in cancers of the gallbladder and extrahepatic biliary tract. British Journal of Cancer 100, 194ı 199.
• Melito, P.L., Woodward, D.L., Bernard, K.A., Price, L . , Khakhria, R., Johnson, W.M., Rodgers, F.G., 2000. Differentiation of clinical Helicobacter pullorum isolates from related Helicobacter and Campylobacter species. Helicobacter 5, 142-147.
• Miller, K.A., Blackall, L . L . , Miflin, J.K., Templeton, J.M., Blackall, P.J., 2006. Detection of Helicobacter pullorum in meat chickens in Australia. Australian Veterinary Journal 84, 95ı
• Neubauer, C . , Hess, M., 2006. Tissue tropism of Helicobacter pullorum in specified pathogen-free chickens determined by culture and nucleic acid detection. Avian Disease 50, 620-623.
• Nilsson, I . , Kornilovs'ka, I . , Lindgren, S., Ljungh, Ä., Wadström, T., 2003. Increased prevalence of seropositivity for non-gastric Helicobacter species in patients with autoimmune liver disease. Journal of Medicine Microbiology 52, 949-953.
• O'rourke, J . L . , Grehan, M., Lee, A., 2001. Non- pylori Helicobacter species in humans. Gut 49, 601-606.
• Pasquali, F . , Rossi, M., Manfreda, G., Zanoni, R., 2007. Complete nucleotide sequence of the gyrA gene of Helicobacter pullorum and identification of a point mutation leading to ciprofloxacin resistance in poultry isolates. International Journal of Antimicrobial Agents 30, 222-228.
• Pellicano, R., Mazzaferro, V., Grigioni, W.F., Cutufia, M.A., Fagoonee, S., Silengo, L . , Rizzetto, M., Ponzetto, A., 2004. Helicobacter species sequences in liver samples from patients with and without hepatocellular carcinoma. World Journal Gastroenterology 10, 598-601.
• Pilon, C., Prouzel-Mauleon, V., Menard, A., Megraud, F . , 2005. Development ofa real-time quantitative PCR specific to Helicobacter pullorum. International Workshop on Campylobacter, Helicobacter and Related Abstracts of Scientific Presentations, September 4-Thirteenth Organisms (CHRO). Abstracts of Scientific Presentations, September 4-8th, Gold Coast, Queensland, Australia, pp. 62.
• Ponzetto, A., Pellicano, R., Leone, N., Cutufia, M.A., Turrini, F . , Grigioni,W.F., D'Errico, A., Mortimer, P., Pizzetto, M., Silengo, L . , 2000. Helicobacter infection and cirrhosis in hepatitis C virus carriage. Is it an innocent bystander or a troublemaker? Medical Hypotheses 54, 275-277.
• Rocha, M., Avenaud, P., Menard, A., Le Bail, B., Balabaud, C., Bioulac-Sage, P., de Magalhaes Queiroz, D.M., Megraud, F., 2004. Association of Helicobacter species with hepatitis C cirrhosis with or without hepatocellular carcinoma. Gut 54, 396-401.
• Stanley, J . , Linton, D., Burnens, A.P., Dewhirst, F . E . , On, S.L.W., Porter, A., 1994. Helicobacter pullorum sp. nov.-genotype and phenotype of a new species isolated from poultry and from human patients with gastroenteritis. Microbiology 140, 3441-3449.
• Starzynska, T., Malfertheiner, P., 2006. Helicobacter and digestive malignancies. Helicobacter 11, 32ı 35.
• Steele, T.W., McDermott, S.N., 1984. The use of membrane filters applied directly to the surface of agar plates for the isolation of Campylobacter jejuni from feces. Pathology 16, 263-265.
• Steinbrueckner, B.G., Hearter, K., Pelz, S., Weiner, J . A., Rump, W., Deissler, S., Bereswill, M , 1997. Isolation of Helicobacter pullorum from patients with enteritis. Scandinavian Journal of Infectious Disease 29, 315-318.
• Taneera, J . , Moran, A.P., Hynes, S.O., Nilsson, H.O., Al-Soud, W., Wadstrom, T., 2002. Influence of activated charcoal, porcine gastric mucin and beta-cyclodextrin on the morphology and growth of intestinal and gastric Helicobacter spp. Microbiology 148, 677-684.
• Varon, C., Duriez, A., Lehours, P., Ménard, A., Layé, S., Zerbib, F., Mégraud, F., Laharie, D., 2009. Study of Helicobacter pullorum proinflammatory properties on human epithelial cells in vitro. Gut 58, 629-635.
• Veijola, L . , Nilsson, I., Halme, L . , Abu Al-Soud, W., Makinen, J . , Ljungh, A., Rautelin, H., 2007. Detection of Helicobacter species in chronic liver dsease and chronic infalammatory bowel disease. Annals of Medicine 39, 554-560.
• Vorobjova, T., Nilsson, I . Terjajev, S., Granholm, M., Lyyra, M., Pokka, T., Prükk, T., Salupere, R., Maaroos, H.I., Wadström, T., Uibo, R., 2006. Serum antibodies to enterohepatic Helicobacter spp. in patients with chronic liver disases and in a population with high prevalence of H. pylori infection. Digestive and Liver Disease 38, 171-176.
• Young, V.B., Chien, C.C., Knox, K.A., Taylor, N.S., Schauer, D.B., Fox, J . G . , 2000. Cytolethal distending toxin in avian and human isolates of Helicobacter pullorum. The Journal of Infectious Diseases 182, 620-623.
• Zanoni, R . G . , Rossi, M., Giacomucci, D.,
• Sanguinetti, V., Manfreda, G., 2007.
• Occurence and antibiotic susceptibility of
• Helicobacter pullorum from broiler chickens
• and commercial laying hens in Italy.
• International Journal of Food Microbiology 116, 168-173.