A CASE OF POLYCYSTIC KIDNEY DISEASE IN A PERSIAN CAT

Year 2009, Volume: 35 Issue: 2, 51 - 56, 20.11.2012

Murat Karabaglı Alev Akdogan Kaymaz

Abstract

ABSTRACT

Feline polycystic kidney disease (PKD) is an inherited autosomal dominant disease that has been identified in Persian cats and Persian related breeds such as the Exotic Shorthair cats. PKD has been reported sporadically in the veterinary literature and progress asymptomaticly until the renal deficiency is observed. Diagnosis of the PKD can be carried out by abdominal ultrasonography and DNA test in 7 weeks old. Our case was a 7 years old male Persian cat which had been brought to Department of Internal Medicine, Faculty of Veterinary Medicine, Istanbul University with complaints such as weight loss, polydipsia, polyuria, lethargy and bilateral enlargement of abdomen. Although the body temperature and outline of the kidneys were normal in physical examination, the cat was lathergic and both of the kidneys was enlarged. At the result of ultrasonographic evaluation, the enlargement of the both kidneys were observed and numerous cysts were determined which were originated from both medulla and cortex of the kidneys and their diameters were changed between 2-15 mm. Although a medical therapy protocol had carried out for the purpose of increasing the quality of his life, the patient was died of 36th day of the treatment.

Key Words: Polycystic kidney disease, persian cats, inherited disease.

 

BİR İRAN KEDİSİNDE POLİKİSTİK BÖBREK HASTALIGI OLGUSU

ÖZET

Polikistik Böbrek Hastalığı (PBH); otozomal dominant bir gen tarafından oluşturulan ve özellikle İran kedileri ile egzotik kedilerde görülen, kalıtsal bir hastalıktır. Sporadik olarak görülen hastalık böbrek yetmezliği gelişene kadar asemptomatik seyreder. Hastalığın tanısı en erken 7 haftalık iken yapılan abdomen ultrasonografisi ve DNA testi ile konulabilir. Olgumuzu karın bölgesinde bilateral şişkinlik, kilo kaybı, politiri, polidipsi ve letarji şikayetleriyle İstanbul Üniversitesi Veteriner Fakültesi İç Hastalıklar Kliniği'ne getirilen 7 yaşında erkek bir İran kedisi oluşturdu. Rutin genel muayenesinde vücut ısısı normal olmasına karşın halsiz olduğu gözlenen hastanın her iki böbreğinin de normal konturlarını kaybettiği ve aşırı büyümüş olduğu saptandı. Abdomenin ultrasonografik muayenesinde her iki böbreğin de büyüdüğü ve her böbrekte de korteks ve medulladan köken alan ve çaplari 2-15 mm arasında değişen, çğk sayıda kistin bulunduğu izlendi. Yaşam kalitesini düzeltmek amacıyla medikal tedavisi düzenlenen hasta 36 gün sonra hayatını kaybetti.

Anahtar Kelimeler: Polikistik böbrek hastalığı, İran kedisi, herediter hastalik.

Keywords

Polikistik böbrek hastalığı, iran kedisi, herediter hastalık

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