KOYUNLARDA DÖL VERİMİNİ VE OVULASYON ORANINI ETKİLEYEN BMP-1B. BMP-15 VE GDF-9 GENLERİNDEKİ MUTASYONLAR

Year 2009, Volume: 35 Issue: 2, 57 - 66, 20.11.2012

Feraye Esen Gürsel

Abstract

ÖZET

Koyunlar 900 farklı ırka sahip oldukları için ovulasyon oranı ve doğurganlık gibi fizyolojik özellikleri büyük çeşitlilik göstermektedir. Koyunların ovulasyon sayısındaki farklılıklar bir grup genin etkisi altındadır. Yapılan çalışmalar sonucunda koyunlardaki döl verimi üzerine etkili transforming growth factor beta (TGFβ) süper ailesinden iki adet yapısal gen ve bir TGFβ reseptör geni tespit edilmiş ve sırasıyla BMP- reseptör 1B (BMP-1B) geni, kemik morfogenetik protein geni (bone morphogenetic protein) (BMP-15) ve büyüme ayrımlaşma faktörü 9b (growth differentiation factor) (GDF-9) geni olarak isimlendirilmişlerdir. Bu makalenin amacı koyunlarda ovulasyon oranı ve döl verimi etkileyen BMP-1B, BMP-15 ve GDF-9 gen mutasyonları ile ilgili bilgileri derlemektir.

Anahtar Kelimeler: Koyun, genetik mutasyon, ovulasyon oranı, döl verimi

 

MUTATIONS IN BMP-1B, BMP-15 AND GDF-9 GENES AND THEIR EFFECTS ON FECUNDITY AND OVULATION RATE IN SHEEP

ABSTRACT

Sheep have more than 900 different breeds. Therefore their physiological characteristics including ovulation rate and fecundity, vary greatly. A group of genes effect the ovulation rates of sheep. Studies showed that there are two structural genes and one receptor gene that are the members of the transforming growth factor beta TGFP family and their names arc BMP-1B. BMP-15 and GDF-9 respectively. In this article we focus on to review the data of the BMP-1B, BMP-15 and GDF-9 gene mutations that effect sheep's ovulation rate and fecundity

Key Words: Sheep, genetic mutation, ovulation rate, fecundity

Keywords

Koyun, genetik mutasyon, ovulasyon oranı, döl verimi

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