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Comparison of St-Segment Duration and Morphology between Clinically Healthy and Diarrheic Holstein Dairy Calves

Year 2014, Volume: 40 Issue: 2, 162 - 167, 22.07.2014

Abstract

ABSTRACT

Several diarrheic (n=52) and clinically healthy (n=21) calves were randomly selected and assigned into 3 age groups, comprising newborn calves (18 to 72 hours; n=31), 15 (n=30) and 30 days old (n=12). Electrocardiograms were recorded on a bipolar base apex lead, using limb lead I and duration, amplitude and morphology of the ST-segment were assessed from successive beats. Serum concentration of sodium, potassium, magnesium and ionized calcium were also determined in all studied animals. ST-segment duration had not significant differences among any groups. Elevation of ST-segment was detected in 75% of healthy newborn calves (amplitude was 0.10±0.03 mV in elevated ST-segments). The ST-segment was elevated in a percent of diarrheic calves; there was elevation in 78.9% (0.14±0.04 mV), 34.6% (0.11±0.04 mV) and 57.1% (0.11±0.04 mV) in newborn, 15 and 30 days old diarrheic calves, respectively. Serum potassium, calcium and magnesium concentrations in all studied diarrheic calves were higher than healthy calves, significantly. It may be stated the electrolyte imbalances in diarrheic calves can induce alterations in ST-segment morphology and the results of the current study may interpret the alterations of ST-segment morphology in diarrheic calves.

Key Words: ST-segment, diarrhea, electrolyte imbalance, calves.

                                                     ÖZET

KLİNİK AÇIDAN SAĞLIKLI VE İSHALLİ SİYAH ALACA IRKI BUZAĞILARDA  ST SEGMENTİNİN SÜRESİNİN KARŞILAŞTIRILMASI 

Çeşitli ishalli (n=52) ve klinik açıdan sağlıklı buzağılar rastgele seçilmiştir ve yeni doğan (18-72 saatler arasında, n=31), 15 (n=30) ve 30 (n=12) günlük buzağıları içeren 3 farklı grup oluşturulmuştur. Elektrokardiyografiler bipolar taban-apeks derivasyonu kullanılarak kaydedildi, bacak derivasyon I ve zamanı, ST segmentinin morfolojisi ve amplitüde ardaşık atımlardan belirlendi. Çalışmaya katılan bütün hayvanlardaki serum sodyum, potasyum, magnezyum ve iyonize kalsiyum konsantrasyonları belirlendi. Gruplar arasında ST segmenti süresi belirgin değişikliklere sahip değildi. Sağlıklı yenidoğan buzağıların %75’inde ST segmentinin artışı belirlendi (artan ST segmentlerindeki amplitüt 0,10±0,03 mV). İshalli buzağıların bir kısmında da ST segmentinde artış oldu. Yeni doğan, 15 ve 30 günlük buzağıların sırasıyla, %78,9 (0,14±0,04 mV), %34,6 (0,11±0,04 mV) ve %57,1 (0,11±0,04 mV)’de olmuştur. Çalışmadaki bütün ishalli buzağılardaki serum potasyum, kalsiyum ve magnezyum konsantrasyonları sağlıklı olanlara göre önemli derecede yüksektir. İshalli buzağılardaki elektrolit dengesizliği ST segment morfolojisindeki bu değişimlere sebep olduğu ve yapılan bu çalışma ile ishalli buzağılardaki ST segmentinin morfolojisindeki değişimlerin yorumlanabileceği belirtilebilir.

Anahtar Kelimeler: ST segmenti, ishal, elektrolit dengesizliği, buzağı

 

References

  • Antzelevitch, C., 2001. The Brugada syndrome: diagnostic criteria and cellular mechanisms. European Heart Journal 22, 356-363.
  • Chen, Q., Kirsch, G.E., Zhang, D., Brugada, R., Brugada, J., Brugada, P., Potenza, D., Moya, A., Borggrefe, M., Breithardt, G., OrtizLopez, R., Wang, Z., Antzelevitch, C., O'Brien, R.E., Schulze-Bahr, E., Keating, M.T., Towbin, J.A., Wang, Q., 1998. Genetic basis and molecular mechanisms for idiopathic ventricular fibrillation. Nature 392, 293-296.
  • Deroth, L., 1980. Electrocardiographic parameters in the normal lactating Holstein cow. Canadian Veterinary Journal 21, 271-277.
  • Gertsch, M., 2009. Electrolyte imbalance and disturbances, In: The ECG Manual: An Evidence-Based Approach. Springer, pp. 1771
  • GhiŃă, M., Cotor, G., Brăslasu, C., 2008a. The values of ECG parameters in newborn calves. Bulletin UASVM, Veterinary Medicine 65, 473.
  • GhiŃă, M., Cotor, G., Brăslasu, C., 2008b. The values of some ECG components in dairy cows, using Dubois leads. Bulletin UASVM, Veterinary Medicine 65, 474.
  • Grant, A.O., 2001. Molecular biology of sodium channels and their role in cardiac arrhythmias. American Journal of Medicine 110, 296-305.
  • Ha¨ggmark, S., Haney, M.F., Jensen, S.M., Johansson, G., Na¨slund, U., 2005. STsegment deviations during pacing-induced increased heart rate in patients without coronary artery disease. Clinical Physiology and Functional Imaging 25, 246-252.
  • Hashimoto, H., Suzuki, K., Miyake, S., Nakashima, M., 1983. Effects of calcium antagonists on the electrical alternans of the ST segment and on associated mechanical alternans during acute coronary occlusion in dogs. Circulation 68, 6676
  • Mendes, L.C.N., Camacho, A.A., Alves, A.L.G., Borges, A.S., Souza, R.C.A., Ferreira, W.L., 200 Standard electrocardiographic values in Holstein calves. Arquivo Brasileiro de Medicina Veterinária e Zootecnia 53, 641-644. Milhorn, H.T., 2005. The electrocardiogram. In: Electrocardiography for the Family Physician, the Essentials. Brown Walker Press 11.
  • Nagy, D., 2009. Resuscitation and critical care of neonatal calves. Veterinary Clinics of North America: Food Animal Practice 25, 1-11.
  • Nattel, S., Turmel, N., Macleod, R., Solymoss, B.C., 19 Actions of intravenous magnesium on ventricular arrhythmias caused by acute myocardial infarction. The Journal of Pharmacology and Experimental Therapeutics 259, 939-946. Nishi, S.P., Barbagelata, N.A., Atar, S., Birnbaum, Y., Tuero, E., 2006. Hypercalcemia-induced ST-segment elevation mimicking acute myocardial infarction. Journal of Electrocardiology 39, 298-300.
  • Pourjafar, M., Badie, K., Chalmeh, A., 2012. Evaluation of ST-segment duration and morphology of standard base apex lead electrocardiograms in different age groups of apparently healthy Holstein cattle. Journal of the Faculty of Veterinary Medicine Istanbul University 38, 51-57.
  • Radostits, O.M., Gay, C.C., Hinchcliff, K.W., Constable, P.D., 2007. Diseases of the cardiovascular system, In: Veterinary Medicine: A Text Book of the Diseases of Cattle, Horses, Sheep, Pigs and Goats. 10 th ed., Elsevier, pp. 399-4
  • Santamarina, G., Espino, L., Suarez, L.M., 2001. Electrocardiographic parameters of free-ranging roe deer (Capreolus capreolus). Journal of Zoo and Wild Life Medicine 32, 441-446.
  • Towbin, J.A., 2001. Ventricular tachycardia or conduction disease: what is the mechanism of death associated with SCN5A? Journal of Cardiovascular Electrophysiology 12, 637-688. Wang, K., Asinger, R.W., Marriott, H.J.L., 2003. ST-segment elevation in conditions other than acute myocardial infarction. The New England Journal of Medicine 349, 2128-2135.
  • Yan, G.X., Antzelevitch, C., 1999. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation 100, 1660-1666.

KLİNİK AÇIDAN SAĞLIKLI VE İSHALLİ SİYAH ALACA IRKI BUZAĞILARDA ST SEGMENTİNİN SÜRESİNİN KARŞILAŞTIRILMASI

Year 2014, Volume: 40 Issue: 2, 162 - 167, 22.07.2014

Abstract

 

 

 

References

  • Antzelevitch, C., 2001. The Brugada syndrome: diagnostic criteria and cellular mechanisms. European Heart Journal 22, 356-363.
  • Chen, Q., Kirsch, G.E., Zhang, D., Brugada, R., Brugada, J., Brugada, P., Potenza, D., Moya, A., Borggrefe, M., Breithardt, G., OrtizLopez, R., Wang, Z., Antzelevitch, C., O'Brien, R.E., Schulze-Bahr, E., Keating, M.T., Towbin, J.A., Wang, Q., 1998. Genetic basis and molecular mechanisms for idiopathic ventricular fibrillation. Nature 392, 293-296.
  • Deroth, L., 1980. Electrocardiographic parameters in the normal lactating Holstein cow. Canadian Veterinary Journal 21, 271-277.
  • Gertsch, M., 2009. Electrolyte imbalance and disturbances, In: The ECG Manual: An Evidence-Based Approach. Springer, pp. 1771
  • GhiŃă, M., Cotor, G., Brăslasu, C., 2008a. The values of ECG parameters in newborn calves. Bulletin UASVM, Veterinary Medicine 65, 473.
  • GhiŃă, M., Cotor, G., Brăslasu, C., 2008b. The values of some ECG components in dairy cows, using Dubois leads. Bulletin UASVM, Veterinary Medicine 65, 474.
  • Grant, A.O., 2001. Molecular biology of sodium channels and their role in cardiac arrhythmias. American Journal of Medicine 110, 296-305.
  • Ha¨ggmark, S., Haney, M.F., Jensen, S.M., Johansson, G., Na¨slund, U., 2005. STsegment deviations during pacing-induced increased heart rate in patients without coronary artery disease. Clinical Physiology and Functional Imaging 25, 246-252.
  • Hashimoto, H., Suzuki, K., Miyake, S., Nakashima, M., 1983. Effects of calcium antagonists on the electrical alternans of the ST segment and on associated mechanical alternans during acute coronary occlusion in dogs. Circulation 68, 6676
  • Mendes, L.C.N., Camacho, A.A., Alves, A.L.G., Borges, A.S., Souza, R.C.A., Ferreira, W.L., 200 Standard electrocardiographic values in Holstein calves. Arquivo Brasileiro de Medicina Veterinária e Zootecnia 53, 641-644. Milhorn, H.T., 2005. The electrocardiogram. In: Electrocardiography for the Family Physician, the Essentials. Brown Walker Press 11.
  • Nagy, D., 2009. Resuscitation and critical care of neonatal calves. Veterinary Clinics of North America: Food Animal Practice 25, 1-11.
  • Nattel, S., Turmel, N., Macleod, R., Solymoss, B.C., 19 Actions of intravenous magnesium on ventricular arrhythmias caused by acute myocardial infarction. The Journal of Pharmacology and Experimental Therapeutics 259, 939-946. Nishi, S.P., Barbagelata, N.A., Atar, S., Birnbaum, Y., Tuero, E., 2006. Hypercalcemia-induced ST-segment elevation mimicking acute myocardial infarction. Journal of Electrocardiology 39, 298-300.
  • Pourjafar, M., Badie, K., Chalmeh, A., 2012. Evaluation of ST-segment duration and morphology of standard base apex lead electrocardiograms in different age groups of apparently healthy Holstein cattle. Journal of the Faculty of Veterinary Medicine Istanbul University 38, 51-57.
  • Radostits, O.M., Gay, C.C., Hinchcliff, K.W., Constable, P.D., 2007. Diseases of the cardiovascular system, In: Veterinary Medicine: A Text Book of the Diseases of Cattle, Horses, Sheep, Pigs and Goats. 10 th ed., Elsevier, pp. 399-4
  • Santamarina, G., Espino, L., Suarez, L.M., 2001. Electrocardiographic parameters of free-ranging roe deer (Capreolus capreolus). Journal of Zoo and Wild Life Medicine 32, 441-446.
  • Towbin, J.A., 2001. Ventricular tachycardia or conduction disease: what is the mechanism of death associated with SCN5A? Journal of Cardiovascular Electrophysiology 12, 637-688. Wang, K., Asinger, R.W., Marriott, H.J.L., 2003. ST-segment elevation in conditions other than acute myocardial infarction. The New England Journal of Medicine 349, 2128-2135.
  • Yan, G.X., Antzelevitch, C., 1999. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation 100, 1660-1666.
There are 17 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Aliasghar Chalmeh

Mehrdad Pourjafar This is me

Mojtaba Naghıb This is me

Publication Date July 22, 2014
Published in Issue Year 2014 Volume: 40 Issue: 2

Cite

APA Chalmeh, A., Pourjafar, M., & Naghıb, M. (2014). Comparison of St-Segment Duration and Morphology between Clinically Healthy and Diarrheic Holstein Dairy Calves. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, 40(2), 162-167. https://doi.org/10.16988/iuvfd.67933
AMA Chalmeh A, Pourjafar M, Naghıb M. Comparison of St-Segment Duration and Morphology between Clinically Healthy and Diarrheic Holstein Dairy Calves. iuvfd. July 2014;40(2):162-167. doi:10.16988/iuvfd.67933
Chicago Chalmeh, Aliasghar, Mehrdad Pourjafar, and Mojtaba Naghıb. “Comparison of St-Segment Duration and Morphology Between Clinically Healthy and Diarrheic Holstein Dairy Calves”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 40, no. 2 (July 2014): 162-67. https://doi.org/10.16988/iuvfd.67933.
EndNote Chalmeh A, Pourjafar M, Naghıb M (July 1, 2014) Comparison of St-Segment Duration and Morphology between Clinically Healthy and Diarrheic Holstein Dairy Calves. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 40 2 162–167.
IEEE A. Chalmeh, M. Pourjafar, and M. Naghıb, “Comparison of St-Segment Duration and Morphology between Clinically Healthy and Diarrheic Holstein Dairy Calves”, iuvfd, vol. 40, no. 2, pp. 162–167, 2014, doi: 10.16988/iuvfd.67933.
ISNAD Chalmeh, Aliasghar et al. “Comparison of St-Segment Duration and Morphology Between Clinically Healthy and Diarrheic Holstein Dairy Calves”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 40/2 (July 2014), 162-167. https://doi.org/10.16988/iuvfd.67933.
JAMA Chalmeh A, Pourjafar M, Naghıb M. Comparison of St-Segment Duration and Morphology between Clinically Healthy and Diarrheic Holstein Dairy Calves. iuvfd. 2014;40:162–167.
MLA Chalmeh, Aliasghar et al. “Comparison of St-Segment Duration and Morphology Between Clinically Healthy and Diarrheic Holstein Dairy Calves”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, vol. 40, no. 2, 2014, pp. 162-7, doi:10.16988/iuvfd.67933.
Vancouver Chalmeh A, Pourjafar M, Naghıb M. Comparison of St-Segment Duration and Morphology between Clinically Healthy and Diarrheic Holstein Dairy Calves. iuvfd. 2014;40(2):162-7.