Nasal Carriage of Methicillin-Resistant Coagulase Negative Staphylococci (MR-CoNS) Among Veterinarians and Veterinary Students

Year 2015, Volume: 41 Issue: 1, 69 - 78, 05.01.2015

Mehmet Yılmaz Özkan Aslantaş , Burçin Özer Ebru Yılmaz

Abstract

The aim of this work was to determine the nasal carriage of methicillin resistant coagulase negative staphylococci (MR-CoNS) among veterinarians and veterinary students. In addition, species distribution, antimicrobial susceptibility, resistance genes and staphylococcal chromosomal cassette mec (SCCmec) type of the isolates were also investigated. MR-CoNS were isolated from 43.8% (39/89) of veterinarians and 44.6% (37/83) of students. While all MR-CoNS isolates were susceptible to quinopristin-dalfopristine, 64.5% of the isolates showed multi-resistance. MR-CoNS strains carried single or various combinations of resistance genes. SCCmec type IV and V were the most common in MR-CoNS strains from both veterinarians and students. This study shows that the rate of nasal carriage of multi-resistant MR-CoNS carriage among veterinarians and veterinary students is high.

Keywords

Methicillin resistance, Staphylococcus spp., veterinarian, veterinary students, nasal carriage, antibiotic susceptibility

Veteriner Hekim ve Veteriner Fakültesi Öğrencilerinde Nazal Metisilin Dirençli Stafilokok (MD-KNS) Taşıyıcılığı

Abstract

Bu çalışmada veteriner hekimler (n=89) ve veteriner fakültesi öğrencileri (n=83) arasında nazal metisilin dirençli koagulaz negatif stafilokok (MD-KNS) taşıyıcılığının saptanması amaçlandı. Ayrıca, izolatların tür dağılımı, antimikrobiyal duyarlılıkları, antibiyotik direnç genleri ve stafilokokal kaset kromozom mec (SCCmec) tipleri de araştırıldı. MD-KNS veteriner hekimlerin %43,8’inden (38/89) ve öğrencilerin %44,6’sından (37/83) izole edildi. MD-KNS suşlarının tamamı kinopristin-dalfopristine duyarlı bulunurken; izolatların %64,5’ı çoğul dirençlilik gösterdi. MD-KNS suşları direnç genlerinin tek veya farklı kombinasyonlarını taşıdı. Hem veteriner hekimlerden hem de öğrencilerden izole edilen MD-KNS suşlarında SCCmec tip IV ve V en yaygın tipler olarak belirlendi. Bu çalışma, veteriner hekimler ve veteriner fakültesi öğrenciler arasında nazal çoğul dirençli MD-KNS taşıyıcılık oranının yüksek olduğunu göstermektedir.

Keywords

Metisilin direnci, Staphylococcus spp., veteriner hekim, veteriner fakültesi öğrencisi, nazal taşıyıcılık, antibiyotik duyarlılık

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