Morphological Studies of Local Influence of Implants with Coatings Based on Superhard Compounds on Bone Tissue under Conditions of Induced Trauma

Year 2015, Volume: 41 Issue: 2, 177 - 184, 01.07.2015

Galimzyan Kabırov Faina Shakırova Jean Manırambona İldar Akhtyamov Elmira Gatına Dmitriy Tsıplakov

Abstract

In this paper we analyze the response of bone tissue to a transosseous introduction of implants made of copper (Cu), medical steel 12X18H9T, steel with nitrides of titanium and hafnium coatings (TiN + HfN), as well as steel coated with titanium and zirconium nitrides (TiN + ZrN) into the diaphysis of the tibia of experimental rats. The obtained results showed that the restoration of the injured bone and bone marrow in groups with implants made of steel 12X18H9T occurred without the participation of the granulation and cartilaginous tissues, but with implants made of steel coated with titanium and hafnium  nitrides (TiN + HfN), this bone recovery also took place in the early term. At the same time, in groups, where the implants were made of copper (Cu), implants were made of steel coated with titanium and zirconium nitrides (TiN + ZrN) were used, such phenomena as necrosis, lysis and destruction of the bone were registered and the bone tissue repair went through formation of the cartilaginous tissue.

Keywords

Rat, implants, nitrides of titan and hafnium, nitrides of titan and zirconium

Aşırı Sert Bileşiklerle Kaplı İmplantların İndüklenmiş Travma Altında Kemik Dokusu Üzerine Lokal Etkilerinin Morfolojik Yönden Araştırılması

Abstract

Bu çalışmada, deney grubundaki sıçanların tibialarının diafizleri içine bakır (Cu), medikal çelik 12X18H9T, titanium ve hafnium nitrit kaplı çelik (TiN + HfN) ve titanium ve zirkonium nitrit (TiN + ZrN) kaplı çelikten yapılmış implantların transosseoz uygulamalarına kemik dokusunun verdiği cevap araştırılmıştır. Elde edilen sonuçlar 12X18H9Tçelikten yapılmış implantlı gruplarda hasarlı kemik ve kemik iliği onarımının granülasyon ve kartilajlı dokuların ayrılması olmadan gerçekleştiğini göstermektedir; öte yandan titanium ve hafrium nitrit (TiN + HfN) ile kaplı çeliklerle yapılmış implantlarda da bu kemik iyileşmesi erken evrede oluşmuştur. Aynı zamanda, bakırdan (Cu) yapılan implantlı gruplar ile titanium ve zirkonium nitrit (TiN + ZrN) ile kaplı çelikten yapılmış implant kullanılan gruplarda kemik nekrozu, dağılması ve bozulması gibi durumlar belirlenmiş ve kemik doku onarımı kartilaj dokusunun oluşumu ile meydana gelmiştir.

Keywords

Sıçan, implantlar, titan ve hafrium nitritleri, titan ve zirkonyum nitritleri

References

• Alexandrova, O.V., Radostina, T.N., Kozlov, N.A., 1987. The cytology, histology and embriology. Agropromizdat, Moscow, pp.255-365.
• Almazov, I.V., Sutulov, L.S., 2002. Atlas of Histology and Embryology. Medicine, Moscow, pp.214-364.
• Alsabeeha, N.H., Swain, M.V., Payne, A.G., 2011. Clinical performance and material properties of single-implant over denture attachment systems.The International Journal of Prosthodontics 24, 247-254.
• Berchenko, G.N., 2001. Bioactive calcium phosphate materials (CPM) and stimulation of reparative osteogenesis: In: Collection Bioimplantologiya of the 21 Century, Moscow, 37-38. on the Verge of
• Berchenko, G.N., 2002. Diseases of the Osteoarticular System. In: Paltseva M.A, Paukova V.S., Ulumbekova E.G. (Eds) Pathology (Business), Moscow, Geotar Med., pp. 565- 597.
• Branemark, P.I., 1959. Vital microscopy of bone marrow in rabbit. Scandinavian Journal of Clinical and Laboratory Investigation 11, 111-82.
• Branemark, P.I., 1983. Osseointegration and its experimental studies. The Journal of Prosthetic Dentistry 50, 399- 410.
• Creuziger A., Crone, W.C, 2008. Initial transformation around a notch tip in CuAlNi: Experiment and modeling, Acta Materialia 56, 518-526.
• Davies, J.E., 1998. Mechanisms of endosseous integration. The International Journal of Prosthodontics 11, 391-401.
• Endo, K., Sachdeva, R., Araki, Y., Ohno, H., 1994. Effects of titanium nitride coatings on surface and corrosion characteristics of Ni-Ti alloy. Dental Materials Journal 13, 228-239.
• Gasch, M., Ellerby, D., Irby, E., Beckman, S., Gusman, M., Johnson, S., 2004. Processing, properties and arc jet oxidation of hafnium diboride/silicon carbide ultra high temperature ceramics Journal of Materials Science 39, 5925-5937.
• Ivanov, P.A., Sokolov, V.A., Bialik, E.I., Vorontsov, Y.A., 2008. Prevention and treatment of complications of the locked closed nailing of long bone fractures in patients with multiple injuries. Journal of Traumatology and Orthopedics 2, 29-32.
• Marco, F, Milena, F, Gianluca, G, Vittoria, O., 2005. Periimplant osteogenesis in health and osteoporosis. Micron 36, 630-644.
• Murai, K, Takeshita, F, Ayukawa, Y, Kiyoshima, T, Suetsugu, T, Tanaka, T., 1996. Light and electron microscopic studies of bone-titanium interface in the tibiae of young and mature rats. Journal of Biomedical Materials Research 30, 523-533.
• Nelson, L.S, 2002. Copper. In: Goldfrank's Toxicologic Emergencies (7th Ed.). McGraw-Hill Companies,New York, pp. 1262-1271
• Sokolov, V.I., Chumakov, E.I, 2004. The cytology, histology, embriologiya. KolosS, Moscow, pp. 143-263.
• Srivatsan, T.S., Guruprasad, G., Zelin, M., Radhakrishnan, R., Sudarshan, T.S., 2007. An investigation of carbon content microstructure and properties of hafnium boride ceramic. Journal of Materials Engineering and Performance 16, 757-765. temperature on
• Yoshinari, M., Oda, Y., Kato, T., Okuda, K., 2001. Influence of surface modifications to titanium on antibacterial activity in vitro. Biomaterials 22, 2043-2048.