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Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor

Year 2017, Volume: 43 Issue: 1, 74 - 76, 01.01.2017
https://doi.org/10.16988/iuvfd.266473

Abstract

    The transmissible venereal
tumor (TVT) is a contagious and sexually transmissible neoplasia of unknown origin.
In natural conditions the tumor mainly affects the external genitalia of both
male and female dogs. A 6- year old male German shepherd dog, weighing 16 kg
was presented for evaluation of a mass on the nasal cavity which the owner had
noticed 2 months ago. Clinical examination revealed multiple nodular ulcerated
lesions of varying sizes from 1 to 3 cm in diameter over the nasal cavity. The
tumor mass had a firm consistency, was hyperemic and ulcerated.
Histopathological examination showed uniform-sized dense cells arranged in
solid sheets and clusters interlaced by a little connective-tissue stroma. The
cells were round and ovoid, with a moderate amount of cytoplasm that was either
clear or finely granular and had a large nuclear/ cytoplasmic ratio. On the
basis of the clinicopathological findings, this mass was diagnosed as a
transmissible venereal tumor.

References

  • Behera, S.K., Kurade, N.P., Monsang, S.W., Das, D.P., Mishra, K.K., Mohanta, R.K., 2012. Clinicopathological findings in a case of canine cutaneous metastatic transmissible venereal tumor. Veterinarski Arhiv 82 (4), 401-410.
  • Cohen, D., 1985. The canine transmissible venereal tumor: a unique result of tumor progression. Advances in Cancer Research 43, 75-112.
  • Coskan, A.S., Alcigir, M.E., Vural, S.A., 2011. Pathomorphological and immunohistochemical findings in a case of extragenital canine transmissible veneral tumor. Bulgarian Journal of Veterinary Medicine 14, 252-256.
  • Das, U., Das, A.K., 2000. Review of canine transmissible venereal tumor sarcoma. Veterinary research communications 24, 545-556.
  • Ferreira, A.J., Jaggy, A., Varejao, A.P., Ferreira, M.L., Correia, J.M., Mulas, J.M., Almeida, O., Oliveira, P., Prada J. 2000. Brain and ocular metastases from a transmissible venereal tumor in a dog. Journal of Small Animal Practice 41, 165-168.
  • Goldschmidt, M.H., Hendrick, M.J., 2002. Tumors in domestic animals. In: Meuten, D.J. (Ed.), Tumors of the skin and soft tissues. 4th ed., Iowa State Press, Ames, Iowa, USA, pp. 45-48.
  • Mukaratirwa, S., Gruys, E., 2004. Canine transmissible venereal tumour: cytogenetic origin, immunophenotype, and immunobiology. A review. Veterinary Quarterly 25, 101–111.
  • Papazoglou, L.G., Koutinas, A.F., Plevraki, A.G., Tontis, D., 2001. Primary intranasal Transmissible Venereal Tumour in the dog: a retrospective study of six spontaneous cases. J Vet Med A Physiol Pathol Clin Med 48, 391-400.
  • Prasad, A.A., Vijayanand, V., Rajasudaram, R.C., Balachandram, C., 2007. Cutaneous transmissible venereal tumor in a dog. Indian Veterinary Journal 84, 978-979.
  • Park, M.S., Kim, Y., Kang, M.S., Oh, S.Y., Cho, D.Y., Shin, N.S., Kim, D.Y., 2006. Disseminated transmissible venereal tumor in a dog. Journal of Veterinary Diagnostic Investigation 18, 130-133.
  • Santos, F.G.A., Vasconcelos, A.C., Nunes, J.E.S., Cassali, G.D., Paixao T.A., Moro, L., 2005. The canine Transmissible Venereal Tumor General Aspects and Molecular Approach (Review). Bioscience Journal 21, 41-53.
  • Otomo, K., Koike, T., Kudo, T., Sakai, T., 1981. Histological and ultrastructural findings of regressing canine transmissible venereal tumor after repeated transplantation. Japanese Journal of Veterinary Science 43, 823-832.
  • Temitope, A.A., Adetola, A.R., Folashade, M.A., Olutayo, O.T., Edem, A.R., Olubukola, N.H., Babajide, K.O., 2010. Radiographic assessment of canine transmissible venereal tumor metastases. Communications in Theriogenology 4, 1-11.

Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor

Year 2017, Volume: 43 Issue: 1, 74 - 76, 01.01.2017
https://doi.org/10.16988/iuvfd.266473

Abstract

    The transmissible venereal
tumor (TVT) is a contagious and sexually transmissible neoplasia of unknown origin.
In natural conditions the tumor mainly affects the external genitalia of both
male and female dogs. A 6- year old male German shepherd dog, weighing 16 kg
was presented for evaluation of a mass on the nasal cavity which the owner had
noticed 2 months ago. Clinical examination revealed multiple nodular ulcerated
lesions of varying sizes from 1 to 3 cm in diameter over the nasal cavity. The
tumor mass had a firm consistency, was hyperemic and ulcerated.
Histopathological examination showed uniform-sized dense cells arranged in
solid sheets and clusters interlaced by a little connective-tissue stroma. The
cells were round and ovoid, with a moderate amount of cytoplasm that was either
clear or finely granular and had a large nuclear/ cytoplasmic ratio. On the
basis of the clinicopathological findings, this mass was diagnosed as a
transmissible venereal tumor.

References

  • Behera, S.K., Kurade, N.P., Monsang, S.W., Das, D.P., Mishra, K.K., Mohanta, R.K., 2012. Clinicopathological findings in a case of canine cutaneous metastatic transmissible venereal tumor. Veterinarski Arhiv 82 (4), 401-410.
  • Cohen, D., 1985. The canine transmissible venereal tumor: a unique result of tumor progression. Advances in Cancer Research 43, 75-112.
  • Coskan, A.S., Alcigir, M.E., Vural, S.A., 2011. Pathomorphological and immunohistochemical findings in a case of extragenital canine transmissible veneral tumor. Bulgarian Journal of Veterinary Medicine 14, 252-256.
  • Das, U., Das, A.K., 2000. Review of canine transmissible venereal tumor sarcoma. Veterinary research communications 24, 545-556.
  • Ferreira, A.J., Jaggy, A., Varejao, A.P., Ferreira, M.L., Correia, J.M., Mulas, J.M., Almeida, O., Oliveira, P., Prada J. 2000. Brain and ocular metastases from a transmissible venereal tumor in a dog. Journal of Small Animal Practice 41, 165-168.
  • Goldschmidt, M.H., Hendrick, M.J., 2002. Tumors in domestic animals. In: Meuten, D.J. (Ed.), Tumors of the skin and soft tissues. 4th ed., Iowa State Press, Ames, Iowa, USA, pp. 45-48.
  • Mukaratirwa, S., Gruys, E., 2004. Canine transmissible venereal tumour: cytogenetic origin, immunophenotype, and immunobiology. A review. Veterinary Quarterly 25, 101–111.
  • Papazoglou, L.G., Koutinas, A.F., Plevraki, A.G., Tontis, D., 2001. Primary intranasal Transmissible Venereal Tumour in the dog: a retrospective study of six spontaneous cases. J Vet Med A Physiol Pathol Clin Med 48, 391-400.
  • Prasad, A.A., Vijayanand, V., Rajasudaram, R.C., Balachandram, C., 2007. Cutaneous transmissible venereal tumor in a dog. Indian Veterinary Journal 84, 978-979.
  • Park, M.S., Kim, Y., Kang, M.S., Oh, S.Y., Cho, D.Y., Shin, N.S., Kim, D.Y., 2006. Disseminated transmissible venereal tumor in a dog. Journal of Veterinary Diagnostic Investigation 18, 130-133.
  • Santos, F.G.A., Vasconcelos, A.C., Nunes, J.E.S., Cassali, G.D., Paixao T.A., Moro, L., 2005. The canine Transmissible Venereal Tumor General Aspects and Molecular Approach (Review). Bioscience Journal 21, 41-53.
  • Otomo, K., Koike, T., Kudo, T., Sakai, T., 1981. Histological and ultrastructural findings of regressing canine transmissible venereal tumor after repeated transplantation. Japanese Journal of Veterinary Science 43, 823-832.
  • Temitope, A.A., Adetola, A.R., Folashade, M.A., Olutayo, O.T., Edem, A.R., Olubukola, N.H., Babajide, K.O., 2010. Radiographic assessment of canine transmissible venereal tumor metastases. Communications in Theriogenology 4, 1-11.
There are 13 citations in total.

Details

Subjects Health Care Administration
Journal Section Case Report
Authors

Ghasem Farjanıkısh This is me

Publication Date January 1, 2017
Published in Issue Year 2017 Volume: 43 Issue: 1

Cite

APA Farjanıkısh, G. (2017). Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, 43(1), 74-76. https://doi.org/10.16988/iuvfd.266473
AMA Farjanıkısh G. Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor. iuvfd. January 2017;43(1):74-76. doi:10.16988/iuvfd.266473
Chicago Farjanıkısh, Ghasem. “Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 43, no. 1 (January 2017): 74-76. https://doi.org/10.16988/iuvfd.266473.
EndNote Farjanıkısh G (January 1, 2017) Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 43 1 74–76.
IEEE G. Farjanıkısh, “Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor”, iuvfd, vol. 43, no. 1, pp. 74–76, 2017, doi: 10.16988/iuvfd.266473.
ISNAD Farjanıkısh, Ghasem. “Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 43/1 (January 2017), 74-76. https://doi.org/10.16988/iuvfd.266473.
JAMA Farjanıkısh G. Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor. iuvfd. 2017;43:74–76.
MLA Farjanıkısh, Ghasem. “Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, vol. 43, no. 1, 2017, pp. 74-76, doi:10.16988/iuvfd.266473.
Vancouver Farjanıkısh G. Morphoathological Description of an Extra Genital Canine Transmissible Venereal Tumor. iuvfd. 2017;43(1):74-6.