Histopathological and immunohistochemical characteristics of ventricular ependymoma in a goat

Year 2017, Volume: 43 Issue: 1, 77 - 80, 01.01.2017

Ghasem Farjanıkısh Azizollah Khodakaram-taftı

https://doi.org/10.16988/iuvfd.267285

Abstract

    Ependymomas as primary
central nervous system neoplasms are occasionally observed in human infants
however; they are rare in animals. A three-year-old male goat was presented
with clinical neurological signs. At necropsy, a 3×2×2 cm, bulging, white-grey-
to red, soft mass extending into the left lateral ventricle of brain was
observed. Microscopically, the mass with densely cellular population was
nonencapsulated, mostly containing cuboidal-columnar neoplastic cells with
pseudo-rosettes formation. Mitotic figures were rare and malignancy indexes
were not observed. Neoplastic cells were immunohistochemically positive for Glial
Fibrillary Acidic Protein (GFAP), S-100, and vimentin; however, they did not
express Cytokeratins. On the basis of the location, histologic and
immunohistochemical findings, the tumor was diagnosed as an ependymoma.

Keywords

Ependymoma, goat, immunohistochemistry

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