Antibacterial, Antioxidant, Antidiabetic Potentials and Chemical Composition of Nicotiana glauca Graham Leaf Extract
Abstract
The purpose of this study is to investigate the chemical composition and potentiality of Nicotiana glauca G. leaf extract taken from the Turkish Republic of Northern Cyprus (TRNC), such as antibacterial, antioxidant, and antidiabetic compounds. In February 2020, a leaf of N. glauca was gathered in the Kyrenia district of Northern Cyprus. Methanol was used to extract the leaf sample. The content of essential oils in the extract was determined using gas chromatography and a headspace system test. Several methods were used to investigate the extract's antibacterial, antioxidant activities, and antidiabetic potential. On all microorganisms examined, the leaf methanol extract of N. glauca had no antibacterial activity. Total phenolic and flavonoid content, 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, ferric reducing antioxidant power, metal chelating, and phosphomolybdenum assays were all active with the methanol extract. The extract showed no antidiabetic efficacy. Furthermore, the essential oil was not found in the extract's chemical composition. According to the findings, the presence of antioxidant components in N. glauca leaf extract can protect against the detrimental effects of free radicals. Its application in Northern Cyprus becomes even more crucial as a result of this potential feature.
Keywords
Bioactive compounds, doctor tree, methanol extract, Northern Cyprus
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