Effect of Medetomidine-Butorphanol-Ketamine (Kitty Magic) Anaesthesia In Quails

Ömer Kırgız; Gökhan Akçakavak

doi:10.35229/jaes.1709040

EN TR

Effect of Medetomidine-Butorphanol-Ketamine (Kitty Magic) Anaesthesia In Quails

Abstract

The use of injectable anesthetics in avian species is an essential practice in veterinary medicine, offering a simpler and safer alternative to inhalational agents. This study aimed to investigate the clinical, biochemical and histopathological effects of the Kitty Magic protocol, which consists of a combination of ketamine, butorphanol and medetomidine, on quail (Coturnix coturnix japonica). Clinical parameters, including heart rate (HR), respiratory rate (RR), and cloacal temperature, were monitored before and after anesthesia. HR and RR significantly decreased during the procedure, while cloacal temperature dropped progressively, with a notable reduction by the 60th minute. Biochemical analysis revealed significant changes in AST, ALP, GLU, BUN, and CRE, indicating potential alterations in liver and kidney function. Histopathological examination showed vacuolar degeneration of hepatocytes, renal tubular degeneration, desquamation, congestion, and inflammatory cell infiltration. The findings suggest that the Kitty Magic protocol is a safe and effective anesthetic option for short-term procedures in avian species. However, the observed histopathological changes, particularly in the liver and kidneys, indicate the need for careful monitoring during repeated or prolonged use of this protocol. The study emphasizes the importance of considering both biochemical and histopathological effects in evaluating the safety and efficacy of anesthetic protocols in avian medicine.

Keywords

Coturnix coturnix japonica , clinical parameter , monitorization , histopathology , biochemistry

Bıldırcınlarda Medetomidin-Butorfanol-Ketamin (Kitty Magic) Anestezisinin Etkisi

Öz

Kuş türlerinde enjekte edilebilir anesteziklerin kullanımı veteriner hekimlikte önemli bir uygulamadır ve inhalasyon ajanlarına göre daha basit ve daha güvenli bir alternatif sunmaktadır. Bu çalışmanın amacı ketamin, butorfanol ve medetomidin kombinasyonundan oluşan Kitty Magic protokolünün bıldırcın (Coturnix coturnix japonica) üzerindeki klinik, biyokimyasal ve histopatolojik etkilerini araştırmaktır. Kalp atım hızı (KAH), solunum hızı (SAH) ve kloakal sıcaklık gibi klinik parametreler anestezi öncesinde ve sonrasında izlenmiştir. HR ve RR işlem sırasında önemli ölçüde azalırken, kloakal sıcaklık 60. dakikada kayda değer bir azalma ile aşamalı olarak düştü. Biyokimyasal analizler AST, ALP, GLU, BUN ve CRE değerlerinde önemli değişiklikler olduğunu ortaya koyarak karaciğer ve böbrek fonksiyonlarında potansiyel değişikliklere işaret etti. Histopatolojik incelemede hepatositlerde vakuolar dejenerasyon, renal tübüler dejenerasyon, deskuamasyon, konjesyon ve enflamatuar hücre infiltrasyonu görülmüştür. Bulgular, Kitty Magic protokolünün kuş türlerinde kısa süreli prosedürler için güvenli ve etkili bir anestezi seçeneği olduğunu göstermektedir. Bununla birlikte, özellikle karaciğer ve böbreklerde gözlenen histopatolojik değişiklikler, bu protokolün tekrarlanan veya uzun süreli kullanımı sırasında dikkatli bir izleme ihtiyacına işaret etmektedir. Bu çalışma, kuş hekimliğinde anestezi protokollerinin güvenlik ve etkinliğinin değerlendirilmesinde hem biyokimyasal hem de histopatolojik etkilerin dikkate alınmasının önemini vurgulamaktadır.

Anahtar Kelimeler

Coturnix coturnix japonica , klinik parametre , monitorizasyon , histopatoloji , biyokimya

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Details

Primary Language

English

Subjects

Veterinary Surgery , Veterinary Pathology

Journal Section

Research Article

Authors

Ömer Kırgız ^*
0000-0002-0222-1363
Türkiye

Gökhan Akçakavak
0000-0001-5949-4752
Türkiye

Early Pub Date

September 15, 2025

Publication Date

September 30, 2025

Submission Date

May 29, 2025

Acceptance Date

August 5, 2025

Published in Issue

Year 2025 Volume: 10 Number: 5

DOI

https://doi.org/10.35229/jaes.1709040

IZ

https://izlik.org/JA47XK49YP

APA

Kırgız, Ö., & Akçakavak, G. (2025). Effect of Medetomidine-Butorphanol-Ketamine (Kitty Magic) Anaesthesia In Quails. Journal of Anatolian Environmental and Animal Sciences, 10(5), 580-587. https://doi.org/10.35229/jaes.1709040

EBSCOHost Scilit CABI

JAES/AAS-Journal of Anatolian Environmental and Animal Sciences/Anatolian Academic Sciences&Anadolu Çevre ve Hayvancılık Dergisi/Anadolu Akademik Bilimler-AÇEH/AAS

Effect of Medetomidine-Butorphanol-Ketamine (Kitty Magic) Anaesthesia In Quails

Abstract

Keywords

Bıldırcınlarda Medetomidin-Butorfanol-Ketamin (Kitty Magic) Anestezisinin Etkisi

Öz

Anahtar Kelimeler

References

Details

Primary Language

Subjects

Journal Section

Authors

Early Pub Date

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

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