Significant Bacterial Zoonosis of Cats; Helicobacter Heilmannii

Yıl 2021, Cilt: 6 Sayı: 3, 333 - 340, 28.09.2021

Güvenç Gökalp , Ayşe Birsen Gökalp

https://doi.org/10.35229/jaes.891405

Cited By: 1

Öz

The incidence of H.heilmannii bacteria, which has a zoonotic character in cats, has been reported only in the cases by the literatures in both animals and humans. The presence and possible prevalence of this bacterium should not be overlooked, especially in cat owners or people sharing the same environment as cats. H.heilmannii, which can be shown as one of the possible causes of mucosa-associated lymphoid tissue lymphoma (MALT) in humans, has a lower incidence in humans compared to cats in studies so far, and it assumes that transmission can generally progress from cats to humans. Cats may have typical symptoms of chronic active gastritis similar to humans clinically. It should not be forgotten that the characteristic morphology of the agent should be determined by staining methods in addition to the Urea breath test, PCR, urease test and gastric biopsy methods that can be used for early diagnosis

Anahtar Kelimeler

Cat, Zoonosis, H.heilmannii, MALT, Diagnosis

Kedilerin Önemli Bakteriyel Zoonozu; Helicobacter Heilmannii

Öz

Kedilerde zoonotik karaktere sahip olan H.heilmannii bakterisinin hem hayvanda hem de insanda görülme sıklığı sadece olgular dahilinde literatürlerce belirtilmiş bununla ilgili daha geniş bir hastalık ve etken taraması yapılmamıştır. Özellikle kedi sahipleri veya kedilerle aynı çevreyi paylaşan insanlarda bu bakterinin varlığı ve olası yaygınlığı gözardı edilmemelidir. İnsanlarda mukoza ilişkili lenfoid doku lenfoması (MALT) ‘ın olası nedenleri arasında da gösterilebilen H.heilmannii’nin şimdiye kadar yapılan çalışmalarda insanlardaki insidansının kedilere nazaran daha az olması bulaşmanın genellikle kedilerden insanlara doğru seyir gösterebileceğini varsaymaktadır. Kedilerde ise klinik olarak insanlara benzer şekilde tipik kronik aktif gastritis belirtileri görülebilmektedir. Erken dönemdeki teşhis için kullanılabilen Üre nefes testi, PCR, üreaz testi ve gastrik biyopsi yöntemlerinin yanısıra etkenin karakteristik morfolojisinin boyama yöntemleri ile saptanması gerekliliği unutulmamalıdır.

Anahtar Kelimeler

Kedi, Zoonoz, H.heilmannii, MALT, Teşhis

Kaynakça

• Alzoubi, H., Al-Mnayyis, A., Al rfoa, I., Aqel A., Abu-Lubad M. & Hamdan, O. (2020). The Use of 13C-Urea Breath Test for Non-Invasive Diagnosis of Helicobacter pylori Infection in Comparison to Endoscopy and Stool Antigen Test. Diagnostics, 10(7), 448.
• Atkinson, N.S.S. & Braden, B. (2016). Helicobacter Pylori Infection: Diagnostic Strategies in Primary Diagnosis and After Therapy. Digestive Diseases and Sciences, 61(1), 19-24.
• Bahadori, A., De Witte, C., Agin, M., De Bruyckere, S. & Smet, A. (2018). Presence of gastric Helicobacter species in children suffering from gastric disorders in Southern Turkey. Helicobacter, 23, 1-6.
• Berlamont, H., De Witte, C. & Bauwens, E. (2020). Distinct transcriptome signatures of Helicobacter suis and Helicobacter heilmannii strains upon adherence to human gastric epithelial cells. Veterinary Research, 51(1), 62.
• Blois, S. (2020). Helicobacter infection in small animals. MSD Manual Veterinary Manual, Erişim tarihi: 10.12.2020, https://www.msdvetmanual.com/digestive-system/diseases-of-the-stomach-and-intestines-in-small- animals/helicobacter-infection-in-small-animals.
• De Sousa, D.A., Da Silva, K.S.V.G.C., Cascon, C.M., Silva, F.B.F. & De Mello, M.F.V. (2019). Epidermal growth factor receptor 2 immunoexpression in gastric cells of domestic cats with H. heilmannii infection. Acta Histochemica, 121(4), 413-418.
• Elyasi, B., Rezaie, A., Bakhtiari, N.M. & Mosallanejad, B. (2020). Helicobacter genus in the intestine and liver of stray cats: the molecular, histopathological, and immunohistochemical study. Brazilian Journal of Microbiology, 51(4), 2123-2132.
• Flahou, B., Haesebrouck, F. & Smet, A. (2016). Helicobacter pylori Research, In: Backert, S. & Yamaoka, Y. (Ed), Non-Helicobacter pylori Helicobacter Infections, 1st ed., 233-269p, Springer, Japan.
• García, P.R., Van der Pol, S., Van Asselt, A.D.I., Postma, M., Rodríguez-Ibeas, R., Juárez-Castelló, C.A., González, M. & Antoñanzas F. (2021). Efficiency of Diagnostic Testing for Helicobacter pylori Infections—A Systematic Review. Antibiotics, 10(1), 55.
• Goji, S., Tamura, Y., Sasaki, M., Nakamura, M., Matsui, H. & Yamagata Murayama, S. (2015). Helicobacter suis-Infected Nodular Gastritis and a Review of Diagnostic Sensitivity for Helicobacter heilmannii- Like Organisms. Case Reports in Gastroenterology, 9(2), 179-187.
• Goldstein, E.J.C. & Abrahamian, F.M. (2015). Diseases transmitted by cats. Microbiology Spectrum, 3(5), 1-14.
• Gonciarz, W., Lechowicz, L., Urbaniak, M., Kaca, W. & Chmiela, M. (2021). Use of Fourier-Transform Infrared Spectroscopy (FT-IR) for Monitoring Experimental Helicobacter pylori Infection and Related Inflammatory Response in Guinea Pig Model. International Journal of Molecular Sciences, 22(1), 281.
• Gökalp, G. (2013). Köpeklerde Helikobakter Enfeksiyonlarının C14 Üre Nefes Testi ve Polimeraz Zincir Reaksiyonu (PCR) ile Belirlenmesi ve Tedavisi. Ondokuz Mayıs Üniversitesi Sağlık Bilimleri Enstitüsü. Samsun, Türkiye, 78s.
• Hernandez, C., Serrano, C.A., Villagran, A., Torres, J., Venegas, A. & Harris, P.R. (2016). Helicobacter pylori vacA virulence factor in uncultured Helicobacter heilmannii sensu lato from an infected child. JMM Case Reports, 3(2), 1-7.
• Hong, S., Chung, Y., Kang, W.G., Cho,i Y.S. & Kim, O. (2015). Comparison of three diagnostic assays for the identification of Helicobacter spp. in laboratory dogs. Laboratory Animal Research, 31(2), 86-92.
• Hong, S., Chung, Y., Kang, W.G. & Kim, O. (2016). Detection of Helicobacter felis in a cat with gastric disease in laboratory animal facility. Laboratory Animal Research, 32(2), 122-127.
• Joosten, M., Lindén, S., Rossi, M., Tay, A.C.Y. & Skoog, E. (2016). Divergence between the Highly Virulent Zoonotic Pathogen Helicobacter heilmannii and Its Closest Relative, the Low-Virulence “Helicobacter ailurogastricus” sp. nov. Infection and Immunity, 84(1), 293-306.
• Joosten, M., (2017). The zoonotic pathogen Helicobacter heilmannii from feline origin: aspects of virulence and gastric colonization. Ghent University, Faculty of Veterinary Medicine. Ghent, Belgium, 259s.
• Jung, K., Kim, D.H., Seo, H.I., Gong, E.J. & Bang, C.S. (2021). Efficacy of eradication therapy in Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma: A metaanalysis. Helicobacter, 00:e12774.
• Kubota-Aizawa, S., Ohno, K., Kanemoto, H., Nakashima, K. & Fukushima, K. (2017). Epidemiological study on feline gastric Helicobacter spp. in Japan. The Journal of Veterinary Medical Science, 79(5), 876-880.
• Liu, J., He, L., Haesebrouck, F., Gong, Y. & Flahou, B. (2014). Prevalence of Coinfection with Gastric Non-Helicobacter pylori Helicobacter (NHPH) Species in Helicobacter pylori-infected Patients Suffering from Gastric Disease in Beijing, China. Helicobacter, 20(4), 284–290.
• Majumber, R., Mishra, P., Samal, S.C., Bhat, S.J. & Patra, S. (2020). Helicobacter heilmannii associated gastritis: Report of a rare case. Indian Journal of Pathology and Microbiology, 63(3), 1-3.
• Matos, R., De Witte, C., Smet, A., Berlamont, H., De Bruyckere, S. & Amorim, I. (2020). Antimicrobial Susceptibility Pattern of Helicobacter heilmannii and Helicobacter ailurogastricus Isolates. Microorganisms, 8(6), 957.
• Mladenova-Hristova, I., Grekova, O. & Patel, A. (2017). Zoonotic potential of Helicobacter spp. Journal of Microbiology, Immunology and Infection, 50(3), 265- 269.
• Mohammadi, M., Abadi, A.T.B., Rahimi, F. & Forootan, M. (2019). Helicobacter heilmannii Colonization Is Associated with High Risk for Gastritis. Archives of Medical Research, 50(7), 423-427.
• Nakamura, M., Øverby, A., Murayama, S.Y., Michimae, H. & Matsui, H. (2020). PCR analysis and specific immunohistochemistry revealing a high prevalence of non- Helicobacter pylori Helicobacters in Helicobacter pylori-negative gastric disease patients in Japan: High susceptibility to an Hp eradication regimen. Helicobacter, 25(5), 1-13.
• Nakamura, M., Øverby, A., Murayama, S.Y., Suzuki, H. & Takahashi, T. (2016). Helicobacter pylori, In: Suzuki, H., Warren, R. & Marshall B. (Ed). Gastric Non-Helicobacter pylori Helicobacter: Its Significance in Human Gastric Diseases, 1st ed., 131-142p, Springer, Japan.
• Ostahi, I.A., Villanacci, V. & Crisafulli, V. (2017). Human Helicobacter heilmannii-like organisms infection. 29th European Congress of Pathology, 2 – 6 September 2017, Amsterdam, The Netherlands, 25.
• Pan, X., Ke, H., Niu, X., Li, S., Lv, J. & Pan, L. (2018). Protection Against Helicobacter pylori Infection in BALB/c Mouse Model by Oral Administration of Multivalent Epitope Based Vaccine of Cholera Toxin B Subunit-HUUC. Frontiers in Immunology, 9, 1-12.
• Park, H.S., Jeong, H.Y., Kim, Y.S., Seo, C.S. & Kwon, H.J. (2020). Anti-microbial and anti-inflammatory effects of Cheonwangbosim-dan against Helicobacter pylori-induced gastritis. Journal of Veterinary Sciences, 21(3), 1-15.
• Péré-Védrenne, C., Flahou, B., Loke, M.F.& Vadivelu, J. (2017). Other Helicobacters, gastric and gut microbiota. Helicobacter, 22(1), 1-7.
• Rychlik, A. & Kaczmar, E. (2020). Endoscopic Biopsies and Histopathological Findings in Diagnosing Chronic Gastrointestinal Disorders in Dogs and Cats.Veterinary Medicine International. 1-8.
• Sabbagh, P., Javanian, M., Koppolu, V. &Vasigala, V.R. (2019). Helicobacter pylori infection in children: an overview of diagnostic methods. European Society of Clinical Microbiology,. 38(6):1035-1045.
• Sabbagh, P., Mohammadnia-Afrouzi, M., Javanian, M. & Babazadeh, A. (2019). Diagnostic methods for Helicobacter pylori infection: ideals, options, and limitations. European Journal of Clinical Microbiology & Infectious Diseases, 38(1), 55-66.
• Shafaie, S., Kaboosi, H. & Ghadikolaii, F.P. (2020). Prevalence of non Helicobacter pylori gastric Helicobacters in Iranian dyspeptic patients. BMC Gastroenterology, 20(1), 1-7.
• Shiotani, A., Dore, M.P. & Graham, D.Y. (2016). Helicobacter pylori, In: Suzuki, H., Warren, R. & Marshall B. (Ed). Urea Breath Test and Rapid Urease Test, 1st ed.,143-155p, Springer, Japan.
• Sikiric, P. & Brzozowski, T. (2020).Physiological and Pharmacological Mechanisms in Gastrointestinal Protection, Ulcer Healing and Mucosal Repair - An Update. Current Pharmaceutical Design, 26(25), 2933-2935.
• Takemura, L.S., Marcasso, R.A., Lorenzetti, E. & Alfieri, A.A. (2019). Helicobacter infection in the hepatobiliary system and hepatic lesions: a possible association in dogs. Brazilian Journal of Microbiology, 50(1), 297-305.
• Tolbert, K. & Gould, E. (2020). Clinical Small Animal Internal Medicine, In: Bruyette, D.S. (Ed). Gastritis and Gastric Ulceration in Dogs and Cats, 1st ed., 547-557p, Wiley Blacwell, USA.
• Ülgen, S., Ergin, S., Şennazlı, G. & Bakırel, U. (2016). Detection of Helicobacter heilmannii type II and Helicobacter pylori in dogs and their role in the development of gastritis. Turkish Journal of Veterinary and Animal Sciences 40, 81-88.