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An Innovative Approach in The Field of Health: Nanoparticles/Nanomedicine

Year 2022, Volume: 7 Issue: 3, 304 - 313, 30.09.2022
https://doi.org/10.35229/jaes.1136335

Abstract

Since diseases began to play a role in human history, people have sought ways to heal and prevent disease. This struggle started in hunter-gatherer communities that lived tens of thousands of years ago and has survived to the present day. Nanotechnology is one of the current stops of today's modern medicine, which includes fine techniques that people with the mission of healing diseases in ancient times cannot even imagine.
In this review, nanoparticles, which is product of nanotechnology, are classified according to various methods and the methods used during their preparation are mentioned. The underlying principles of nanoparticles being used as drug delivery, imaging and vaccine adjuvants, and toxicity of nanoparticles have been investigated. Some of the nanoparticle applications that are currently used in veterinary medicine and have the potential to be applied in the future are also mentioned.

References

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  • Bakker-Woudenberg, I.A., Schiffelers, R.M., Storm, G., Becker, MJ, & Guo, L. (2005). Long-circulating sterically stabilized liposomes in the treatment of infections. Methods in Enzymology, 391, 228–260.
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  • Bawa, R. (2008). Nanoparticle-based therapeutics in humans: a survey. Nanotechnology Law & Business, 5, 135.
  • Bentolila, L.A., Ebenstein, Y. & Weiss, S. (2009). Quantum dots for in vivo small-animal imaging. Journal of Nuclear Medicine, 50(4), 493–496.
  • Boverhof, D.R., Bramante, C.M., Butala, J.H., Clancy, S.F., Lafranconi, M., West, J. & Gordon, S.C. (2015). Comparative assessment of nanomaterial definitions and safety evaluation considerations. Regulatory Toxicology and Pharmacology, 73(1), 137–150.
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  • Cai, Z., Wang, Y., Zhu, L.J. & Liu, Z.Q. (2010). Nanocarriers: a general strategy for enhancement of oral bioavailability of poorly absorbed or pre-systemically metabolized drugs. Current Drug Metabolisms, 11(2), 197–207.
  • Carmona, E.R., Plaza, T., Recio-Sanchez, G. & Parodi, J. (2018). Generation of a protocol for the synthesis of chitosan nanoparticles loaded with florfenicol through the ionic gelation method. Revista de Investigaciones Veterinarias del Perú (RIVEP), 29(4), 1195–1202.
  • Cordeiro, C., Wiseman, D.J., Lutwyche, P., Uh, M., Evans, J.C., Finlay, B.B. & Webb, M.S. (2000). Antibacterial efficacy of gentamicin encapsulated in pH-sensitive liposomes against an in vivo Salmonella enterica serovar typhimurium intracellular infection model. Antimicrobial Agents and Chemotherapy, 44(3), 533–539.
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  • Gershkovich, P., Wasan, K.M. & Barta, C.A. (2008). A review of the application of lipid-based systems in systemic, dermal/transdermal, and ocular drug delivery. Critical Reviews in Therapeutic Drug Carrier Systems, 25(6), 545–584.
  • Guccione, S., Li, K.C. & Bednarski, M.D. (2004). Vascular-targeted nanoparticles for molecular imaging and therapy. Methods in Enzymology, 386, 219–236.
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  • Hofheinz, R.D., Gnad-Vogt, S.U., Beyer, U. & Hochhaus, A. (2005). Liposomal encapsulated anti-cancer drugs. Anti-cancer Drugs, 16(7), 691–707.
  • Hu, S. & Hsieh, Y.L. (2015). Synthesis of surface bound silver nanoparticles on cellulose fibers using lignin as multi-functional agent. Carbohydrate Polymers, 131, 134–141.
  • Ishihara, T., Takahashi, M., Higaki, M., Mizushima, Y. & Mizushima, T. (2010). Preparation and characterization of a nanoparticulate formulation composed of PEG-PLA and PLA as anti-inflammatory agents. International Journal of Pharmaceutics, 385(1-2), 170–175.
  • Jeevanandam, J., Barhoum, A., Chan, Y.S., Dufresne, A. & Danquah, M.K. (2018). Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations. Beilstein Journal of Nanotechnology, 9(1), 1050–1074.
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Sağlık Alanında Yenilikçi Bir Yaklaşım: Nanopartiküller/Nanotıp

Year 2022, Volume: 7 Issue: 3, 304 - 313, 30.09.2022
https://doi.org/10.35229/jaes.1136335

Abstract

Hastalıklar insanlık tarihinde rol oynamaya başladığından beri insanlar hastalıkları iyileştirmenin ve hastalıklardan korunmanın yollarını aramışlardır. Bu mücadele on binlerce yıl öncesinde yaşamış olan avcı-toplayıcı topluluklarda başlamış, günümüze kadar gelmiştir. Eski çağlarda hastalıkları iyileştirme misyonunu yüklenmiş insanların hayal dahi edemeyeceği ince teknikleri barındıran günümüz modern tıbbının gelmiş olduğu güncel duraklardan birisi de nanoteknolojidir.
Bu derlemede bir nanoteknoloji ürünü olan nanopartiküller çeşitli metotlara göre sınıflandırılmıştır ve hazırlanmaları sırasında kullanılan yöntemlerden bahsedilmektedir. Nanopartiküllerin ilaç iletimi, görüntüleme ve aşı adjuvanları olarak kullanılabilmelerinin altında yatan prensipler ile birlikte nanopartiküllerin toksisitesi konuları incelenmiştir. Nanopartiküllere yönelik veteriner hekimlikte günümüzde kullanılmakta olan ve gelecekte uygulanma potansiyeli bulunan uygulamalardan bazılarına da değinilmiştir.

References

  • Adiseshaiah, P.P., Hall, J.B. & McNeil, S.E. (2010). Nanomaterial standards for efficacy and toxicity assessment. Nanomedicine and Nanobiotechnology, 2(1), 99–112.
  • Agrahari, V. & Agrahari, V. (2018). Facilitating the translation of nanomedicines to a clinical product: challenges and opportunities. Drug Discovery Today, 23(5), 974–991.
  • Agrawal, S., Agrawal, A., Doughty, B., Gerwitz, A., Blenis, J., Van Dyke, T. & Pulendran, B. (2003). Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. Journal of Immunology, 171(10), 4984–4989.
  • Arulsudar, N., Subramanian, N., Mishra, P., Chuttani, K., Sharma, R. & Murthy, R. (2004). Preparation, characterization, and biodistribution study of technetium-99m-labeled leuprolide acetate-loaded liposomes in ehrlich ascites tumor-bearing mice. American Association of Pharmaceutical Scientists, 6(1), 45–56.
  • Bakker-Woudenberg, I.A., Schiffelers, R.M., Storm, G., Becker, MJ, & Guo, L. (2005). Long-circulating sterically stabilized liposomes in the treatment of infections. Methods in Enzymology, 391, 228–260.
  • Bansod, S.D., Bawaskar, M.S., Gade, A.K., & Rai, M.K. (2015). Development of shampoo, soap and ointment formulated by green synthesised silver nanoparticles functionalised with antimicrobial plants oils in veterinary dermatology: treatment and prevention strategies. IET Nanobiotechnology, 9(4), 165–171.
  • Bawa, R. (2008). Nanoparticle-based therapeutics in humans: a survey. Nanotechnology Law & Business, 5, 135.
  • Bentolila, L.A., Ebenstein, Y. & Weiss, S. (2009). Quantum dots for in vivo small-animal imaging. Journal of Nuclear Medicine, 50(4), 493–496.
  • Boverhof, D.R., Bramante, C.M., Butala, J.H., Clancy, S.F., Lafranconi, M., West, J. & Gordon, S.C. (2015). Comparative assessment of nanomaterial definitions and safety evaluation considerations. Regulatory Toxicology and Pharmacology, 73(1), 137–150.
  • Brayden, D.J. (2003). Controlled release technologies for drug delivery. Drug Discovery Today, 8(21), 976–978.
  • Brigger, I., Dubernet, C. & Couvreur, P. (2002). Nanoparticles in cancer therapy and diagnosis. Advanced Drug Delivery Reviews, 54(5), 631–651.
  • British Standards Institute (BSI) (2011). Nanoparticles. Vocabulary. (PAS 71:2011). https://shop.bsigroup.com/en/Browse-By-Subject/Nanotechnology/Terminologies-for-nanotechnologies-/PAS-71. Last accession date: 06.06.2020.
  • Buzea, C., Pacheco, I.I. & Robbie, K. (2007). Nanomaterials and nanoparticles: sources and toxicity. Biointerphases, 2(4), MR17-MR71.
  • Cai, Z., Wang, Y., Zhu, L.J. & Liu, Z.Q. (2010). Nanocarriers: a general strategy for enhancement of oral bioavailability of poorly absorbed or pre-systemically metabolized drugs. Current Drug Metabolisms, 11(2), 197–207.
  • Carmona, E.R., Plaza, T., Recio-Sanchez, G. & Parodi, J. (2018). Generation of a protocol for the synthesis of chitosan nanoparticles loaded with florfenicol through the ionic gelation method. Revista de Investigaciones Veterinarias del Perú (RIVEP), 29(4), 1195–1202.
  • Cordeiro, C., Wiseman, D.J., Lutwyche, P., Uh, M., Evans, J.C., Finlay, B.B. & Webb, M.S. (2000). Antibacterial efficacy of gentamicin encapsulated in pH-sensitive liposomes against an in vivo Salmonella enterica serovar typhimurium intracellular infection model. Antimicrobial Agents and Chemotherapy, 44(3), 533–539.
  • Couvreur, P. & Puisieux, F. (1993). Nano-and microparticles for the delivery of polypeptides and proteins. Advanced Drug Delivery Reviews, 10(2-3), 141–162.
  • Couvreur, P. & Vauthier, C. (2006). Nanotechnology: Intelligent Design to Treat Complex Disease. Pharmaceutical Research, 23(7), 1417–1450.
  • Cubillos, C., de la Torre, B.G., Jakab, A., Clementi, G., Borrás, E., Bárcena, J., Andreu, D., Sobrino, F. & Blanco, E. (2008). Enhanced mucosal immunoglobulin A response and solid protection against foot-and-mouth disease virus challenge induced by a novel dendrimeric peptide. Journal of Virology, 82(14), 7223–7230.
  • El-Sayed, A. & Kamel, M. (2018). Advanced applications of nanotechnology in veterinary medicine. Environmental Science and Pollution Researches International, 27(16),19073–19086.
  • Fahmy, T.M., Samstein, R.M., Harness, C.C. & Saltzman, W.M. (2005). Surface modification of biodegradable polyesters with fatty acid conjugates for improved drug targeting. Biomaterials, 26(28), 5727–5736.
  • Florindo, H.F., Pandit, S., Gonçalves, L.M., Videira, M., Alpar, O. & Almeida, A.J. (2009). Antibody and cytokine-associated immune responses to S. equi antigens entrapped in PLA nanospheres. Biomaterials, 30(28), 5161–5169.
  • Gershkovich, P., Wasan, K.M. & Barta, C.A. (2008). A review of the application of lipid-based systems in systemic, dermal/transdermal, and ocular drug delivery. Critical Reviews in Therapeutic Drug Carrier Systems, 25(6), 545–584.
  • Guccione, S., Li, K.C. & Bednarski, M.D. (2004). Vascular-targeted nanoparticles for molecular imaging and therapy. Methods in Enzymology, 386, 219–236.
  • Hajizade, A., Ebrahimi, F., Salmanian, A.H., Arpanaei, A. & Amani, J. (2014). Nanoparticles in vaccine development. Journal of Applied Biotechnology Reports, 1(4), 125–134.
  • Harpin, S., Hurley, D.J., Mbikay, M., Talbot, B. & Elazhary, Y. (1999). Vaccination of cattle with a DNA plasmid encoding the bovine viral diarrhoea virus major glycoprotein E2. Journal of General Virology, 80, 3137–3144.
  • Hiszczyńska-Sawicka, E., Olędzka, G., Holec-Gąsior, L., Li, H., Xu, J.B., Sedcole, R., Kur, J., Bickerstaffe, R. & Stankiewicz, M. (2011). Evaluation of immune responses in sheep induced by DNA immunization with genes encoding GRA1, GRA4, GRA6 and GRA7 antigens of Toxoplasma gondii. Vet Parasitol;177(3-4):281–289.
  • Hofheinz, R.D., Gnad-Vogt, S.U., Beyer, U. & Hochhaus, A. (2005). Liposomal encapsulated anti-cancer drugs. Anti-cancer Drugs, 16(7), 691–707.
  • Hu, S. & Hsieh, Y.L. (2015). Synthesis of surface bound silver nanoparticles on cellulose fibers using lignin as multi-functional agent. Carbohydrate Polymers, 131, 134–141.
  • Ishihara, T., Takahashi, M., Higaki, M., Mizushima, Y. & Mizushima, T. (2010). Preparation and characterization of a nanoparticulate formulation composed of PEG-PLA and PLA as anti-inflammatory agents. International Journal of Pharmaceutics, 385(1-2), 170–175.
  • Jeevanandam, J., Barhoum, A., Chan, Y.S., Dufresne, A. & Danquah, M.K. (2018). Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations. Beilstein Journal of Nanotechnology, 9(1), 1050–1074.
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There are 76 citations in total.

Details

Primary Language English
Journal Section Articles
Authors

Volkan Enes Ergüden 0000-0003-2215-2868

Alper Çiftci 0000-0001-8370-8677

Publication Date September 30, 2022
Submission Date June 27, 2022
Acceptance Date August 31, 2022
Published in Issue Year 2022 Volume: 7 Issue: 3

Cite

APA Ergüden, V. E., & Çiftci, A. (2022). An Innovative Approach in The Field of Health: Nanoparticles/Nanomedicine. Journal of Anatolian Environmental and Animal Sciences, 7(3), 304-313. https://doi.org/10.35229/jaes.1136335


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