Pyrus elaeagrifolia ve Crithmum maritimum L. Meyve ve Yaprak-Gövde Özütlerinin Antibakteriyel, Antioksidan, Antidiyabetik Potansiyelleri ve Kimyasal Bileşimi

Yıl 2024, Cilt: 9 Sayı: 4, 493 - 500

Melis Sümengen Özdenefe , Fikret Büyükkaya Kayış , Aysun Mercimek Takcı

https://doi.org/10.35229/jaes.1511026

Öz

Bu çalışmanın amacı, Kuzey Kıbrıs Türk Cumhuriyeti'nden (KKTC) toplanan Pyrus elaeagrifolia ve Crithmum maritimum L. meyve ve yaprak-gövde özütlerinin kimyasal bileşimini ve antibakteriyel, antioksidan ve antidiyabetik bileşikler gibi potansiyelini araştırmaktır. Ağustos 2022'de Kuzey Kıbrıs'ın Girne ilçesinde Pyrus elaeagrifolia’nın meyvesi ve Crithmum maritimum’ın yaprak ve gövdesi toplandı. Meyve ve yaprak-gövde örneklerini ekstrakte etmek için metanol kullanıldı. Özütlerin antibakteriyel, antioksidan aktivitelerini ve antidiyabetik potansiyelini araştırmak için çeşitli yöntemler kullanıldı. İncelenen tüm mikroorganizmalar üzerinde, Pyrus elaeagrifolia ve Crithmum maritimum L. meyve ve yaprak-gövde metanol özütlerinin antibakteriyel aktivitesi yoktu. Toplam fenolik ve flavonoid içeriği, 1,1-difenil-2-pikrilhidrazil radikal süpürme aktivitesi, ferrik indirgeyici antioksidan gücü, metal şelatlama ve fosfomolibden deneylerinin tümü metanol özütleri ile aktifti. Özütler antidiyabetik etkinlik göstermedi. Elde edilen bulgulara göre, Pyrus elaeagrifolia ve Crithmum maritimum L. meyve ve yaprak-gövde özütlerinde antioksidan bileşenlerin bulunması, serbest radikallerin zararlı etkilerine karşı koruma sağlayabiliyor. Bu potansiyel özelliği nedeniyle Kuzey Kıbrıs'ta uygulanması daha da önem kazanmaktadır.

Anahtar Kelimeler

Biyoaktif bileşikler, Crithmum maritimum L., Kuzey Kıbrıs, metanol özütü, Pyrus elaeagrifolia

Antibacterial, Antioxidant, Antidiabetic Potentials and Chemical Composition of Pyrus elaeagrifolia and Crithmum maritimum L. Fruit and Leaf-Stem Extracts

Öz

The purpose of this study is to investigate the chemical composition and potentiality of Pyrus elaeagrifolia ve Crithmum maritimum L. fruit and leaf-stem extracts collected from the Turkish Republic of Northern Cyprus (TRNC), such as antibacterial, antioxidant, and antidiabetic compounds. In August 2022, a fruit and leaf-stem of Pyrus elaeagrifolia and Crithmum maritimum L. were gathered in the Kyrenia district of Northern Cyprus. Methanol was used to extracts the fruit and leaf-stem samples. Several methods were used to investigate the extract's antibacterial, antioxidant activities, and antidiabetic potential. On all microorganisms examined, the fruit and leaf-stem methanol extracts of Pyrus elaeagrifolia and Crithmum maritimum L. had no antibacterial activity. Total phenolic and flavonoid content, 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, ferric reducing antioxidant power, metal chelating, and phosphomolybdenum assays were all active with the methanol extract. The extract showed no antidiabetic efficacy. According to the findings, the presence of antioxidant components in Pyrus elaeagrifolia and Crithmum maritimum L. fruit and leaf-stem extracts can protect against the detrimental effects of free radicals. Its application in Northern Cyprus becomes even more crucial as a result of this potential feature.

Anahtar Kelimeler

Crithmum maritimum L., Pyrus elaeagrifolia, Bioactive compounds, methanol extract, Northern Cyprus

Kaynakça

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