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Deniz Marulu (Ulva lactuca L. 1753)’nun Antimikrobiyal ve Antioksidan Özellikleri

Year 2025, Volume: 10 Issue: 2, 109 - 114
https://doi.org/10.35229/jaes.1593761

Abstract

Makroalgler çok hücreli ökaryotik organizmalardır ve deniz ekosisteminin çok önemli bir bölümünü oluşturmakta olup, doğada en hızlı büyüme gösteren bitkisel organizmalarıdır. Diğer taraftan gıda, hayvan yemi, ilaç ve kozmetik gibi sektörlerde kullanılabilen, biyolojik aktif bileşikler üretme yeteneğindeki organizmalardır. Ulva lactuca vitaminler, flavonoidler, tanenler, fenoller, polisakkaritler, saponinler ve polisakkaritler içerir ve ayrıca antiinflamatuar ve antikanser etkilere sahiptir. Günümüzde mikroorganizmaların neden olduğu hastalıklarla mücadelede antibiyotikler yaygın olarak kullanılmaktadır. Ancak pek çok yan etkisi olması, bakterilerin bu antibiyotiklere karşı direnç geliştirmesine neden olması ve aynı zamanda mali açıdan külfetli olması nedeniyle bilim adamları, toksik olarak etkisiz olan ya da çok az toksik etkiye sahip olan, aynı zamanda maliyet açısından ucuz olan materyallerden antibiyotik elde etmeye yönelmişlerdir. Günümüzde bu antibiyotiği elde etmek için kullanılan alternatif kaynaklar tıbbi kökenli bitkiler, makrofunguslar ve alglerdir. Bu derlemede makroalgler ve Ulva lactuca'nın antimikrobiyal ve antioksidan özellikleri incelenmiştir.

References

  • Ahmad, B., Shah, M. & Choi, S. (2019). Oceans as a source of immunotherapy. Marine Drugs, 17(5). DOI: 10.3390/md17050282
  • Albayati, M. A. F. (2020). Bazı Makroalg Türlerinin Antimikrobiyal Aktivitelerinin Belirlenmesi. Yüksek Lisans Tezi, Selçuk Üniversitesi Fen Bilimleri Enstitüsü. Konya, 60s.
  • Barzkar, N., Jahromi, S. T., Poorsaheli, H.B. &Vianello, F. (2019). Metabolites from marine microorganisms, micro, and macroalgae: Immense scope for pharmacology. Marine Drugs, 17(8). DOI: 10.3390/md17080464
  • Chen, L., Xu, W., Chen, D., Chen, G., Liu, J., Zeng, X. ve Zhu, H. (2018). Digestibility of sulfated polysaccharide from the brown seaweed Ascophyllum nodosum and its effect on the human gut microbiota in vitro. International Journal of Biological Macromolecules, 112, 1055-1061. DOI: 10.1016/j.ijbiomac.2018.01.183
  • Chung, Y., Jeong, Seula., Lee, I-K., Yun, B-S., Lee, J.S., Ro, S. & Park, J.K. (2021). Regulation of p53 Activity by (+)-Epiloliolide Isolated from Ulva lactuca. Marine Drugs, 19, 450. DOI: 10.3390/md19080450
  • Çebı̇, A., Soylu, E.N. & Kablan, S. (2016). Karadeniz’den toplanan Ulva lactuca L. türünün toplam Antioksidan Kapasitesinin Belirlenmesi. The Black Sea Journal of Sciences, 6(14), 22-29.
  • Çelenk, F.G. (2014). İ zmı̇r körfezı̇ kıyılarındakı̇ bazı makroalglerı̇n antı̇oksı̇dan, sı̇totoksı̇k, hı̇poglı̇semı̇k ve hı̇polı̇pı̇demı̇k etkı̇lerı̇nı̇n araştırılması. Doktora Tezi, Ege Üniversitesi Fen Bilimleri Enstitüsü. İzmir, 189s.
  • Cornish, M. L. & Garbary, D. J. (2010). Antioxidants from macroalgae: potential applications in human health and nutrition. Algae, 25(4), 155-171. DOI: 10.4490/algae.2010.25.4.155
  • Dominguez, H. & Loret, E.P. (2019). Ulva lactuca, A Source of Troubles and Potential Riches. Marine Drugs, 17 (6), 1-20. DOI: 10.3390/md17060357
  • Freile-Pelegrin, Y. & Morales, J.L. (2004). Antibacterial activity in marine algae from the coast of Yucatan, Mexico. Botanica Marina, 47(2), 140-146, DOI: 10.1515/BOT.2004.014
  • Gümüş, B., Ünlüsayın, M. & Gümüş, E. (2018). A review on antimicrobial properties of marine macroalgae extracts. Ege Journal of Fisheries and Aquatic Sciences, 35(3), 343-351. DOI: 10.12714/egejfas.2018.35.3.15
  • Kherraz-Chemlal, D., Khelil, F., Mazouzi, M., Matallah- Boutiba, A. & Bouderbala, M.(2024). Phytochemical Screening of Antioxidant and Antibacterial Activities of Marine Algae Extracts. Polish Journal of Environmental Studies, 34(3), 3199-3206. DOI: 10.15244/pjoes/188450
  • Kidgell, J.T., Magnusson, M., de Nys, R. & Glasson, C.R.K. (2019). Ulvan: A systematic review of extraction, composition and function. Algal Research, 39, 101422. DOI: 10.1016/j.algal.2019.101422
  • Kim, S.K. & Mendis, E. (2006). Bioactive compounds from marine processing byproducts-A review. Food Research International, 39(4), 383-393. DOI: 10.1016/j.foodres.2005.10.010
  • Kolanjinathan, K. & Stella, D. (2009). Antibacterial Activity of Marine Macro Algae against Human Pathogens. Recent Research in Science and Technology, 1, 20-22.
  • Kumar, M., Kumari, P., Gupta, V., Anisha, P.A., Reddy, C.R.K. & Jha, B. (2010). Differential responses to cadmium induced oxidative stress in marine macroalga Ulva lactuca (Ulvales, Chlorophyta). Biometals, 23(2), 315-25. DOI: 10.1007/s10534- 010-9290-8
  • Metin, C. & Baygar, T. (2018). Denizel Kaynaklardan Elde Edilen Biyoaktif Maddeler ve Kozmetik Alanında Kullanımı. Süleyman Demirel Üniversitesi Eğirdir Su Ürünleri Fakültesi Dergisi, 14(4), 339-350. DOI. 10.22392/egirdir.399363
  • Osotprasit, S., Samrit, T., Savedvanich, G., Chaiwichien, A., Changklungmoa, N., Kueakhai, P. & Jaikua, W. (2025). Evaluation of Toxicity and Antioxidant Activity of the Ethanolic Extract from Ulva Lactuca. Trends in Sciences, 22(2), 8812-8812.
  • Öztürk, F. & Hamzaçebi, S. (2019). Farklı Çözgenlerle Elde Edilmiş Ulva lactuca Ekstraktlarının Antibakteriyal Aktivitesi. Acta Aquatica Turcica, 15(3), 272-279.
  • Rezaie, A., Parker, R.D. & Abdollahi, M. (2007). Oxidative stress and pathogenesis of inflammatory bowel disease: an epiphenomenon or the cause? Digestive diseases and sciences, 52, 2015-2021.
  • Şahin, Y. (2012). Karadeniz Kıyılarında Bulunan Bazı Makro Alg Türlerinin Antimikrobiyal Aktivitelerinin Araştırılması. Yüksek Lisans Tezi, Giresun Üniversitesi Fen Bilimleri Enstitüsü, Giresun.
  • Sudhakar, M.P., Kumar, B.R., Mathimani, T. & Arunkumar, K. (2019). A review on bioenergy and bioactive compounds from microalgae and macroalgae-sustainable energy perspective. Journal of Cleaner Production, 228, 1320-1333. DOI: 10.1016/j.jclepro.2019.04.287
  • Taşkın, E., Öztürk, M. & Kurt, O. (2007). Antibacterial activities of some marine algae from the Aegean Sea (Turkey). African Journal of Biotechnology. 6(24), 2746-2751. DOI: 10.5897/AJB2007.000-2439
  • Tong, T., Liu, Ya-J., Zhang, P. & Kang, S.G. (2020). Antioxidant, anti-inflammatory, and α-amylase inhibitory activities of Ulva lactuca extract. Korean Journal of Food Preservation. 27(4), 513-521. DOI: 10.11002/kjfp.2020.27.4.513
  • Torun, Z. & Konuklugil, B. (2020). Prebiotic effects of macroalgae. Ege Journal of Fisheries and Aquatic Sciences, 37(1), 103-112. DOI: 10.12714/egejfas.37.1.12
  • Tüney, I., Çadirci, B. H., Ünal, D. & Sukatar, A. (2006). Antimicrobial activities of the extracts of marine algae from the coast of Urla (İzmir, Turkey). Turkish Journal of Biology, 30(3), 171-175.
  • Tziveleka, L. A., Tammam, M. A., Tzakou, O., Roussis, V. & Ioannou, E. (2021). Metabolites with antioxidant activity from marine macroalgae. Antioxidants, 10, 431. DOI: 10.3390/antiox10091431
  • Wang, H. M. D., Li, X. C., Lee, D. J. & Chang, J. S. (2017). Potential biomedical applications of marine algae. Bioresource Technology, 244, 1407–1415. DOI: 10.1016/j.biortech.2017.05.198

Antimicrobial And Antioxidant Properties of Sea Lettuce (Ulva lactuca L. 1753)

Year 2025, Volume: 10 Issue: 2, 109 - 114
https://doi.org/10.35229/jaes.1593761

Abstract

Macro algae, or more commonly known as algae, are multicellular eukaryotic organisms and form a very important part of the marine ecosystem. Seaweeds are the fastest growing plant organisms in nature. They are living things that can find application in sectors such as medicine, cosmetics, food and animal feed and have the ability to produce biologically active compounds. Ulva lactuca contains vitamins, flavonoids, tannins, phenols, polysaccharides, saponins, and the polysaccharides and also have anti-inflammatory and anticancer effects. Nowadays, antibiotics are widely used to fight diseases caused by microorganisms. However, due to the fact that they have many side effects, cause bacteria to develop resistance to these antibiotics, and are also financially burdensome, scientists have directed scientists to obtain antibiotics from financially cheap sources that have no or negligible toxic effects. Today, the alternative sources used to obtain this antibiotic are plants of medicinal origin, macrofungi and algae. In this review, the antimicrobial and antioxidant characteristics of macroalgae and Ulva lactuca were examined.

References

  • Ahmad, B., Shah, M. & Choi, S. (2019). Oceans as a source of immunotherapy. Marine Drugs, 17(5). DOI: 10.3390/md17050282
  • Albayati, M. A. F. (2020). Bazı Makroalg Türlerinin Antimikrobiyal Aktivitelerinin Belirlenmesi. Yüksek Lisans Tezi, Selçuk Üniversitesi Fen Bilimleri Enstitüsü. Konya, 60s.
  • Barzkar, N., Jahromi, S. T., Poorsaheli, H.B. &Vianello, F. (2019). Metabolites from marine microorganisms, micro, and macroalgae: Immense scope for pharmacology. Marine Drugs, 17(8). DOI: 10.3390/md17080464
  • Chen, L., Xu, W., Chen, D., Chen, G., Liu, J., Zeng, X. ve Zhu, H. (2018). Digestibility of sulfated polysaccharide from the brown seaweed Ascophyllum nodosum and its effect on the human gut microbiota in vitro. International Journal of Biological Macromolecules, 112, 1055-1061. DOI: 10.1016/j.ijbiomac.2018.01.183
  • Chung, Y., Jeong, Seula., Lee, I-K., Yun, B-S., Lee, J.S., Ro, S. & Park, J.K. (2021). Regulation of p53 Activity by (+)-Epiloliolide Isolated from Ulva lactuca. Marine Drugs, 19, 450. DOI: 10.3390/md19080450
  • Çebı̇, A., Soylu, E.N. & Kablan, S. (2016). Karadeniz’den toplanan Ulva lactuca L. türünün toplam Antioksidan Kapasitesinin Belirlenmesi. The Black Sea Journal of Sciences, 6(14), 22-29.
  • Çelenk, F.G. (2014). İ zmı̇r körfezı̇ kıyılarındakı̇ bazı makroalglerı̇n antı̇oksı̇dan, sı̇totoksı̇k, hı̇poglı̇semı̇k ve hı̇polı̇pı̇demı̇k etkı̇lerı̇nı̇n araştırılması. Doktora Tezi, Ege Üniversitesi Fen Bilimleri Enstitüsü. İzmir, 189s.
  • Cornish, M. L. & Garbary, D. J. (2010). Antioxidants from macroalgae: potential applications in human health and nutrition. Algae, 25(4), 155-171. DOI: 10.4490/algae.2010.25.4.155
  • Dominguez, H. & Loret, E.P. (2019). Ulva lactuca, A Source of Troubles and Potential Riches. Marine Drugs, 17 (6), 1-20. DOI: 10.3390/md17060357
  • Freile-Pelegrin, Y. & Morales, J.L. (2004). Antibacterial activity in marine algae from the coast of Yucatan, Mexico. Botanica Marina, 47(2), 140-146, DOI: 10.1515/BOT.2004.014
  • Gümüş, B., Ünlüsayın, M. & Gümüş, E. (2018). A review on antimicrobial properties of marine macroalgae extracts. Ege Journal of Fisheries and Aquatic Sciences, 35(3), 343-351. DOI: 10.12714/egejfas.2018.35.3.15
  • Kherraz-Chemlal, D., Khelil, F., Mazouzi, M., Matallah- Boutiba, A. & Bouderbala, M.(2024). Phytochemical Screening of Antioxidant and Antibacterial Activities of Marine Algae Extracts. Polish Journal of Environmental Studies, 34(3), 3199-3206. DOI: 10.15244/pjoes/188450
  • Kidgell, J.T., Magnusson, M., de Nys, R. & Glasson, C.R.K. (2019). Ulvan: A systematic review of extraction, composition and function. Algal Research, 39, 101422. DOI: 10.1016/j.algal.2019.101422
  • Kim, S.K. & Mendis, E. (2006). Bioactive compounds from marine processing byproducts-A review. Food Research International, 39(4), 383-393. DOI: 10.1016/j.foodres.2005.10.010
  • Kolanjinathan, K. & Stella, D. (2009). Antibacterial Activity of Marine Macro Algae against Human Pathogens. Recent Research in Science and Technology, 1, 20-22.
  • Kumar, M., Kumari, P., Gupta, V., Anisha, P.A., Reddy, C.R.K. & Jha, B. (2010). Differential responses to cadmium induced oxidative stress in marine macroalga Ulva lactuca (Ulvales, Chlorophyta). Biometals, 23(2), 315-25. DOI: 10.1007/s10534- 010-9290-8
  • Metin, C. & Baygar, T. (2018). Denizel Kaynaklardan Elde Edilen Biyoaktif Maddeler ve Kozmetik Alanında Kullanımı. Süleyman Demirel Üniversitesi Eğirdir Su Ürünleri Fakültesi Dergisi, 14(4), 339-350. DOI. 10.22392/egirdir.399363
  • Osotprasit, S., Samrit, T., Savedvanich, G., Chaiwichien, A., Changklungmoa, N., Kueakhai, P. & Jaikua, W. (2025). Evaluation of Toxicity and Antioxidant Activity of the Ethanolic Extract from Ulva Lactuca. Trends in Sciences, 22(2), 8812-8812.
  • Öztürk, F. & Hamzaçebi, S. (2019). Farklı Çözgenlerle Elde Edilmiş Ulva lactuca Ekstraktlarının Antibakteriyal Aktivitesi. Acta Aquatica Turcica, 15(3), 272-279.
  • Rezaie, A., Parker, R.D. & Abdollahi, M. (2007). Oxidative stress and pathogenesis of inflammatory bowel disease: an epiphenomenon or the cause? Digestive diseases and sciences, 52, 2015-2021.
  • Şahin, Y. (2012). Karadeniz Kıyılarında Bulunan Bazı Makro Alg Türlerinin Antimikrobiyal Aktivitelerinin Araştırılması. Yüksek Lisans Tezi, Giresun Üniversitesi Fen Bilimleri Enstitüsü, Giresun.
  • Sudhakar, M.P., Kumar, B.R., Mathimani, T. & Arunkumar, K. (2019). A review on bioenergy and bioactive compounds from microalgae and macroalgae-sustainable energy perspective. Journal of Cleaner Production, 228, 1320-1333. DOI: 10.1016/j.jclepro.2019.04.287
  • Taşkın, E., Öztürk, M. & Kurt, O. (2007). Antibacterial activities of some marine algae from the Aegean Sea (Turkey). African Journal of Biotechnology. 6(24), 2746-2751. DOI: 10.5897/AJB2007.000-2439
  • Tong, T., Liu, Ya-J., Zhang, P. & Kang, S.G. (2020). Antioxidant, anti-inflammatory, and α-amylase inhibitory activities of Ulva lactuca extract. Korean Journal of Food Preservation. 27(4), 513-521. DOI: 10.11002/kjfp.2020.27.4.513
  • Torun, Z. & Konuklugil, B. (2020). Prebiotic effects of macroalgae. Ege Journal of Fisheries and Aquatic Sciences, 37(1), 103-112. DOI: 10.12714/egejfas.37.1.12
  • Tüney, I., Çadirci, B. H., Ünal, D. & Sukatar, A. (2006). Antimicrobial activities of the extracts of marine algae from the coast of Urla (İzmir, Turkey). Turkish Journal of Biology, 30(3), 171-175.
  • Tziveleka, L. A., Tammam, M. A., Tzakou, O., Roussis, V. & Ioannou, E. (2021). Metabolites with antioxidant activity from marine macroalgae. Antioxidants, 10, 431. DOI: 10.3390/antiox10091431
  • Wang, H. M. D., Li, X. C., Lee, D. J. & Chang, J. S. (2017). Potential biomedical applications of marine algae. Bioresource Technology, 244, 1407–1415. DOI: 10.1016/j.biortech.2017.05.198
There are 28 citations in total.

Details

Primary Language Turkish
Subjects Aquaculture, Veterinary Bacteriology, Veterinary Pharmacology, Veterinary Microbiology
Journal Section Articles
Authors

Aybike Türkmen 0000-0002-4119-7490

Selim Sekkin 0000-0002-3795-5375

Early Pub Date March 16, 2025
Publication Date
Submission Date November 30, 2024
Acceptance Date February 6, 2025
Published in Issue Year 2025 Volume: 10 Issue: 2

Cite

APA Türkmen, A., & Sekkin, S. (2025). Deniz Marulu (Ulva lactuca L. 1753)’nun Antimikrobiyal ve Antioksidan Özellikleri. Journal of Anatolian Environmental and Animal Sciences, 10(2), 109-114. https://doi.org/10.35229/jaes.1593761


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