Effect of Medetomidine-Butorphanol-Ketamine (Kitty Magic) Anaesthesia In Quails

Year 2025, Volume: 10 Issue: 5, 580 - 587

Ömer Kırgız , Gökhan Akçakavak

https://doi.org/10.35229/jaes.1709040

Abstract

The use of injectable anesthetics in avian species is an essential practice in veterinary medicine, offering a simpler and safer alternative to inhalational agents. This study aimed to investigate the clinical, biochemical and histopathological effects of the Kitty Magic protocol, which consists of a combination of ketamine, butorphanol and medetomidine, on quail (Coturnix coturnix japonica). Clinical parameters, including heart rate (HR), respiratory rate (RR), and cloacal temperature, were monitored before and after anesthesia. HR and RR significantly decreased during the procedure, while cloacal temperature dropped progressively, with a notable reduction by the 60th minute. Biochemical analysis revealed significant changes in AST, ALP, GLU, BUN, and CRE, indicating potential alterations in liver and kidney function. Histopathological examination showed vacuolar degeneration of hepatocytes, renal tubular degeneration, desquamation, congestion, and inflammatory cell infiltration. The findings suggest that the Kitty Magic protocol is a safe and effective anesthetic option for short-term procedures in avian species. However, the observed histopathological changes, particularly in the liver and kidneys, indicate the need for careful monitoring during repeated or prolonged use of this protocol. The study emphasizes the importance of considering both biochemical and histopathological effects in evaluating the safety and efficacy of anesthetic protocols in avian medicine.

Keywords

Coturnix coturnix japonica , clinical parameter , monitorization , histopathology , biochemistry

Bıldırcınlarda Medetomidin-Butorfanol-Ketamin (Kitty Magic) Anestezisinin Etkisi

Abstract

Kuş türlerinde enjekte edilebilir anesteziklerin kullanımı veteriner hekimlikte önemli bir uygulamadır ve inhalasyon ajanlarına göre daha basit ve daha güvenli bir alternatif sunmaktadır. Bu çalışmanın amacı ketamin, butorfanol ve medetomidin kombinasyonundan oluşan Kitty Magic protokolünün bıldırcın (Coturnix coturnix japonica) üzerindeki klinik, biyokimyasal ve histopatolojik etkilerini araştırmaktır. Kalp atım hızı (KAH), solunum hızı (SAH) ve kloakal sıcaklık gibi klinik parametreler anestezi öncesinde ve sonrasında izlenmiştir. HR ve RR işlem sırasında önemli ölçüde azalırken, kloakal sıcaklık 60. dakikada kayda değer bir azalma ile aşamalı olarak düştü. Biyokimyasal analizler AST, ALP, GLU, BUN ve CRE değerlerinde önemli değişiklikler olduğunu ortaya koyarak karaciğer ve böbrek fonksiyonlarında potansiyel değişikliklere işaret etti. Histopatolojik incelemede hepatositlerde vakuolar dejenerasyon, renal tübüler dejenerasyon, deskuamasyon, konjesyon ve enflamatuar hücre infiltrasyonu görülmüştür. Bulgular, Kitty Magic protokolünün kuş türlerinde kısa süreli prosedürler için güvenli ve etkili bir anestezi seçeneği olduğunu göstermektedir. Bununla birlikte, özellikle karaciğer ve böbreklerde gözlenen histopatolojik değişiklikler, bu protokolün tekrarlanan veya uzun süreli kullanımı sırasında dikkatli bir izleme ihtiyacına işaret etmektedir. Bu çalışma, kuş hekimliğinde anestezi protokollerinin güvenlik ve etkinliğinin değerlendirilmesinde hem biyokimyasal hem de histopatolojik etkilerin dikkate alınmasının önemini vurgulamaktadır.

Keywords

Coturnix coturnix japonica , klinik parametre , monitorizasyon , histopatoloji , biyokimya

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