Bireysel Tıpta Organoidler ve Yapay Zeka

Abstract

Organoidler, organların, dokuların ve hücrelerin simüle edildiği 3 boyutlu in vitro modellerdir. Organoidlerin kök hücre çalışmaları ile modellenerek yapay zeka ile birleştirilmesiyle bilimde yeni bir çağın kapıları açılmıştır. Bireyin kendi genomundan sağlanan veriler ile hastalık mekanizmaları ve tedavi yöntemlerine ilişkin anlayışı yeniden tanımlamaktadır. Bu derleme, organoid çalışmalarındaki yeniliklere genel bir bakış sağlayarak özellikle kök hücrelerden elde edilen organoidlerin kanser ve ilaç araştırmalarında yapay zeka aracılığıyla modellenmesi sonucunda bireysel tıp üzerine etkilerini ortaya koymuştur.

Keywords

• organoidler
• yapay zeka
• bireysel tıp
• kanser
• kök hücre

Organoids and Artificial Intelligence in Personalized Medicine

Abstract

Organoids are 3D in vitro models in which organs, tissues and cells are simulated. A new scientific era was started by organoid modeling with stem cell studies and combining them with artificial intelligence. It redefines the understanding of disease mechanisms and treatment methods with data provided from the individual's own genome. This review provides an overview of the innovations in organoid studies. It also reveals the effects of organoids, especially originating from stem cells, on personalized medicine by modeling them through artificial intelligence in cancer and drug research.

Keywords

• organoids
• artificial intelligence
• personalized medicine
• cancer
• stem cell

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